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Categories: Biology: Biochemistry, Chemistry: Biochemistry

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A deep dive into macroalgae genetics has uncovered the genetic underpinnings that enabled macroalgae, or 'seaweed,' to evolve multicellularity. Three lineages of macroalgae developed multicellularity independently and during very different time periods by acquiring genes that enable cell adhesion, extracellular matrix formation, and cell differentiation, researchers report. Surprisingly, many of these multicellular-enabling genes had viral origins. The study, which increased the total number of sequenced macroalgal genomes from 14 to 124, is the first to investigate macroalgal evolution through the lens of genomics.

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A research team has unearthed new findings which may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from poor diet. The insights gained from this study hold promise for advancing cancer prevention strategies aimed at promoting healthy aging.

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Scientists have summarized microbial food production strategies.

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A collaboration unveils a novel strategy for identifying key proteins in organelle communication. This approach advances our ability to pinpoint proteins essential for organelle interactions within specific spatial and temporal contexts.

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Wildebeest migrations have become a rarer sight in Africa as humans continue to interrupt their historic migratory routes with roads, fences, cities, livestock and farmland. This has led to genetic decay in those herds that are no longer able to roam freely, according to new research.

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The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.

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It is one of the world's most spectacular sights -- huge flocks or 'flamboyances' of flamingos around East Africa's lakes -- as seen in the film Out of Africa or David Attenborough's A Perfect Planet. But new research has revealed how the lesser flamingo is at danger of being flushed out of its historic feeding grounds, with serious consequences for the future of the species.

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Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide. While the immune system usually clears HPV infections, those that persist can lead to cancer, and a new finding suggests that certain women may have a genetic susceptibility for persistent or frequent HPV infections. These genetic variants could raise a woman's risk of getting cervical cancer from a high-risk HPV infection.

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Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.

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Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.

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While there's no regulation in the U.S. for what's in organic shampoos, they tend to contain ingredients perceived as safe or environmentally friendly. However, these 'clean' shampoos separate and spoil faster than those made with synthetic stabilizers and preservatives. Now, researchers demonstrate that a simple process -- spinning organic shampoo at high speeds -- improved the final products' shelf lives and ability to clean hair.

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Tyche is a machine-learning framework that can generate plausible answers when asked to identify potential disease in medical images. By capturing the ambiguity in images, the technique could prevent clinicians from missing crucial information that could inform diagnoses.

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Researchers have created a method that extracts over 80 percent of the available protein in grain leftovers from brewing beer, commonly known as brewers' spent grain.

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Cloud 'engineering' could be more effective for climate cooling than previously thought, because of the increased cloud cover produced, new research shows.

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Researchers have developed synthetic platelets that can be used to stop bleeding and enhance healing at the site of an injury. The researchers have demonstrated that the synthetic platelets work well in animal models but have not yet begun clinical trials in humans.

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Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.

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Traces of DNA in the stomachs of predatory snails give a team og geobiologists new insights into the ecology of placozoans.

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Ant species living in Boulder's foothills have shifted their habitat over the last six decades, potentially affecting local ecosystems, suggests a new study.

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Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.

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Cells contain various specialized structures -- such as the nucleus, mitochondria or peroxisomes -- known as 'organelles'. Tracing their genesis and determining their structure is fundamental to understanding cell function and the pathologies linked to their dysfunction.