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Categories: Biology: Biochemistry, Chemistry: Biochemistry
Published Steroid drugs used for HRT can combat E. coli and MRSA
(via sciencedaily.com) Original source Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane
(via sciencedaily.com) Original source Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.
Published Staying in the loop: How superconductors are helping computers 'remember'
(via sciencedaily.com) Original source To advance neuromorphic computing, some researchers are looking at analog improvements -- advancing not just software, but hardware too. Research shows a promising new way to store and transmit information using disordered superconducting loops.
Published Scientists reveal the first unconventional superconductor that can be found in mineral form in nature
(via sciencedaily.com) Original source Scientists have identified the first unconventional superconductor with a chemical composition also found in nature.
Published High resolution imagery advances the ability to monitor decadal changes in emperor penguin populations
(via sciencedaily.com) Original source Emperor penguin populations have been exceedingly difficult to monitor because of their remote locations, and because individuals form breeding colonies on seasonal sea ice fastened to land (known as fast ice) during the dark and cold Antarctic winter. New research that incorporates very high-resolution satellite imagery with field-based validation surveys and long-term data has provided the first multi-year time series that documents emperor penguin global population trends.
Published Sonic youth: Healthy reef sounds increase coral settlement
(via sciencedaily.com) Original source Healthy coral reefs have rich soundscapes, full of the croaks, purrs, and grunts of various fishes and the crackling of snapping shrimp. Larval coral uses these sounds as cues to identify the best places to settle and grow. The authors found that sound could potentially be a vital tool in the effort to restore coral reefs. Broadcasting the sounds of a healthy reef to a reef that is degraded encourages coral larvae to settle there. This indicates that it's possible that 'acoustic enrichment' can be a key intervention to support imperiled reefs.
Published Simple trick could improve accuracy of plant genetics research
(via sciencedaily.com) Original source Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk
(via sciencedaily.com) Original source An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.
Published Molecular simulations of ammonia mixtures support search for renewable fuels
(via sciencedaily.com) Original source Ammonia is an important molecule with many applications. The end product of the famed Haber-Bosch process, it is commonly synthesized to capture nitrogen for fertilizers, and is used for refrigeration, in cleaning products, and in the production of pharmaceuticals. Recently, this modest molecule has also attracted interest as a potential resource for addressing one of today's most pressing challenges -- the need for reliable and abundant renewable fuels.
Published Study brings scientists a step closer to successfully growing plants in space
(via sciencedaily.com) Original source New, highly stretchable sensors can monitor and transmit plant growth information without human intervention. The polymer sensors are resilient to humidity and temperature, can stretch over 400% while remaining attached to a plant as it grows and send a wireless signal to a remote monitoring location, said a chemical and biomolecular engineering professor.
Published Tsetse fly fertility damaged after just one heatwave, study finds
(via sciencedaily.com) Original source The fertility of both female and male tsetse flies is affected by a single burst of hot weather, researchers have found.
Published A simple and robust experimental process for protein engineering
(via sciencedaily.com) Original source A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Who knew that coprophagy was so vital for birds' survival?
(via sciencedaily.com) Original source New research explains how eating feces (known as coprophagy) shapes wild birds' digestive tracts (gut biota), enabling them to absorb lost or deficient nutrients and adjust to seasonal variations in food sources.
Published Exploring arctic plants and lichens: An important conservation baseline for Nunavut's newest and largest territorial park
(via sciencedaily.com) Original source A comprehensive study of the floristic diversity of Agguttinni Territorial Park, Nunavut's newest and largest Territorial Park, has documented 141 vascular plant, 69 bryophyte, and 93 lichen species from this unique protected area on northern Baffin Island. Through a combination of extensive fieldwork in 2021 and examination of hundreds of existing herbarium specimens, the authors have documented species newly reported for Baffin Island and have crafted a biodiversity baseline important for park management and conservation.
Published Scientists find weak points on Epstein-Barr virus
(via sciencedaily.com) Original source Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
Published A sprayable gel could make minimally invasive surgeries simpler and safer
(via sciencedaily.com) Original source The new GastroShield gel can be sprayed through an endoscope after polyps are removed during colonoscopy, protecting the gut and helping prevent complications from weakened gastrointestinal tissues.
Published How a natural compound from sea squirts combats cancer
(via sciencedaily.com) Original source Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published Rice paddy snake diversification was driven by geological and environmental factors in Thailand, molecular data suggests
(via sciencedaily.com) Original source A new study of rice paddy snakes in Southeast Asia gives key details to their diversification and natural history, adding molecular evidence that the rise of the Khorat Plateau and subsequent environmental shifts in Thailand may have altered the course of the snakes' evolution some 2.5 million years ago.
Published A coral superhighway in the Indian Ocean
(via sciencedaily.com) Original source Despite being scattered across more than a million square kilometers, new research has revealed that remote coral reefs across the Seychelles are closely related. Using genetic analyses and oceanographic modelling, researchers demonstrated for the first time that a network of ocean currents scatter significant numbers of larvae between these distant islands, acting as a 'coral superhighway.'
Published Scientists develop a rapid gene-editing screen to find effects of cancer mutations
(via sciencedaily.com) Original source Researchers found a way to screen cancer-linked gene mutations much more easily and quickly than existing approaches, using a variant of CRISPR genome-editing known as prime editing.