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Categories: Biology: Biochemistry, Chemistry: Biochemistry

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Researchers have identified a new approach to controlling bacterial infections. The team found a way to turn on a vital bacterial defense mechanism to fight and manage bacterial infections. The defense system, called cyclic oligonucleotide-based antiphage signaling system (CBASS), is a natural mechanism used by certain bacteria to protect themselves from viral attacks. Bacteria self-destruct as a means to prevent the spread of virus to other bacterial cells in the population.

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A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.

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Extreme events wipe out entire forests, dramatically eliminating complex ecosystems as well as local communities. Researchers have become quite familiar with such attention-grabbing events over the years. They know less, however, about the more common moderate-severity disturbances, such as relatively small fires, ice storms, and outbreaks of pests or pathogens.

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An international research team has succeeded in controlling the chirality of individual molecules through structural isomerization. The team also succeeded in synthesizing highly reactive diradicals with two unpaired electrons. These achievements were made using a scanning tunneling microscope probe at low temperatures.

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A research group explored how the social evolution of microbes can be manipulated by tuning the physical parameters of the environment in which they live.

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Lithium-sulfur batteries have exceptional theoretical capacity and performance in combination with an element in abundant supply. But the intricate reaction mechanism, particularly during discharge, has been challenging to solve. Researchers have identified the key pathways to a complex sulfur reduction reaction that leads to energy loss and reduced battery life span. The study's findings establish the whole reaction network for the first time and offer insight into electrocatalyst design for improved batteries.

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A research team has solved the mystery of a novel clove-like off-flavor in orange juice, the cause of which was previously unknown. The study proves for the first time that the undesirable flavor note is due to the odorant 5-vinylguaiacol. As the results of the study show, the substance is mainly produced during the pasteurization process when residues of a cleaning agent react with a natural orange juice component under the influence of heat.

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In hydrogen fuel cells, electrolyte membranes frequently undergo deformation and develop cracks during operation. A research team has recently introduced a fatigue-resistant polymer electrolyte membrane for hydrogen fuel cells, employing an interpenetrating network of Nafion (a plastic electrolyte) and perfluoropolyether (a rubbery polymer). This innovation will not only improve fuel cell vehicles but also promises advancements in diverse technologies beyond transportation, spanning applications from drones to desalination filters and backup power sources.

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Researchers have developed a new biocontainment method for limiting the escape of genetically engineered organisms used in industrial processes.

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Researchers studied in detail the strange protist Meteora sporadica, which swings its two lateral arms back and forth. The results of the study indicated that M. sporadica has a complex cytoskeleton that is closely related to Hemimastigophora, a group of organisms considered to be one of the deepest branches of eukaryotes.

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Researchers have discovered peptide factors that function in the shoot and root systems to transport iron into the root nodules colonized by nitrogen-fixing bacteria. Moreover, these peptide factors regulate nitrogen homeostasis by maintaining a balance between nitrogen and iron concentrations in plants without rhizobial symbiosis.

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An experiment spanning more than two decades has found that removal of apex predators from an ecosystem can create lasting changes that are not reversed after they return -- at least, not for a very long time. The study challenges the commonly held belief that the reintroduction of wolves to Yellowstone National Park restored an ecosystem degraded by their absence.

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Influenza A viruses with induced resistance to a new candidate antiviral drug were found to be impaired in cell culture and weakened in animals, according to a new study.

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Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts. Such knowledge opens the door to predictions of which enhancer variants underlie disease in order to harness the full potential of our genomes for better human health.

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Scientists have uncovered important clues to how human T cells combat Mycobacterium tuberculosis, the bacterium that causes TB.

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A crystals expert has published an answer to how crystals are formed and how molecules become a part of them, solving an age-old mystery about crystal formation.

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The workings of the ultrasonic warning sounds produced by the wings of a species of moth have been revealed.

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There was an increase in the number of unprovoked shark attacks worldwide and an uptick in fatalities in 2023 compared to the previous year. A scientific database of global shark attacks, confirmed 69 unprovoked bites in 2023. Although this is higher than the most recent five-year average of 63 attacks, the data remain consistent with long-term trends.

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A recent re-emergence and outbreak of Mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core. Now, a team of researchers lifted the mysteries of poxviral core architecture by combining various cryo-electron microscopy techniques with molecular modeling.

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A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. It will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based immunotherapies.