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Categories: Biology: Biochemistry, Chemistry: Biochemistry
Published Breakthrough in creating cyclic peptide opens the way for new antibiotics



A discovery could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.
Published Brain's structure hangs in 'a delicate balance'



Researchers examined anatomy of neurons from humans, mice and fruit flies. They discovered that the cellular structure of the brain is at a critical point, poised between two phases. New insights could help design computational models of the brain's complexity.
Published Protein study could help researchers develop new antibiotics



A team has found a way to make the bacterial enzyme histidine kinase water-soluble, which could make it possible to rapidly screen potential antibiotics that might interfere with its functions.
Published Researchers engineer new approach for controlling thermal emission



If a material absorbs light, it will heat up. That heat must go somewhere, and the ability to control where and how much heat is emitted can protect or even hide such devices as satellites. An international team of researchers has published a novel method for controlling this thermal emission in Science.
Published Four-legged, dog-like robot 'sniffs' hazardous gases in inaccessible environments



Nightmare material or truly man's best friend? A team of researchers equipped a dog-like quadruped robot with a mechanized arm that takes air samples from potentially treacherous situations, such as an abandoned building or fire. The robot dog walks samples to a person who screens them for potentially hazardous compounds.
Published Fine-tuning leaf angle with CRISPR improves sugarcane yield



A CABBI research team has used CRISPR/Cas9 gene editing to optimize leaf angle in sugarcane, increasing the amount of sunlight it captures and the amount of biomass it produces.
Published Two can play that game: juvenile dolphins who play together are more successful as adults



Juvenile social play predicts adult reproductive success in male bottlenose dolphins, a new study has found.
Published Protocol for creating 'wired miniature brains'



Researchers have developed -- and shared -- a process for creating brain cortical organoids -- essentially miniature artificial brains with functioning neural networks.
Published Researchers create skin-inspired sensory robots to provide medical treatment



Scientists have created innovative soft robots equipped with electronic skins and artificial muscles, allowing them to sense their surroundings and adapt their movements in real-time.
Published How human derived RNA fragments help the Hepatitis E virus



Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year. Repeated sequencing of the virus RNA showed that the virus incorporated various parts of the host's messenger RNA into its genome. This resulted in a replication advantage, which may have contributed to the infection becoming chronic.
Published Miniaturizing a laser on a photonic chip



Scientists have successfully miniaturized a powerful erbium-based biber laser on a silicon-nitride photonic chip. Since typical erbium-based fiber lasers are large and difficult to scale down, the breakthrough promises major advances in optical communications and sensing technologies.
Published Splitting hairs: Science of biomechanics to understand of bad hair days



Academics are often accused of 'splitting hairs', but a team has now devised a machine to do just that. We all have a bad hair day from time to time, and split ends are a common problem. However, the science behind this kind of hair damage is poorly understood, which is why scientists are investigating this knotty problem.
Published Gut microbes from aged mice induce inflammation in young mice, study finds



When scientists transplanted the gut microbes of aged mice into young 'germ-free' mice -- raised to have no gut microbes of their own -- the recipient mice experienced an increase in inflammation that parallels inflammatory processes associated with aging in humans. Young germ-free mice transplanted with microbes from other young mice had no such increase.
Published Epitope binning-seq: A game-changer in antibody drug discovery



Antibody drug discovery is an extremely laborious and tedious process. Epitope Binning-seq, a novel method, introduces a groundbreaking approach by enabling simultaneous analysis of multiple antibodies. Using a fluorescently labeled reference antibody (rAb), this method employs flow cytometry to identify similar epitope-binding query antibodies (qAbs). Next-generation sequencing of fluorescence-negative cells then groups qAbs with epitopes akin to the rAb into epitope bins. This innovative technique holds immense potential in enhancing antibody drug discovery process.
Published Novel Genetic Clock discovers oldest known marine plant



An international research team has discovered the oldest known marine plant using a novel genetic clock. This 1400-year-old seagrass clone from the Baltic Sea dates back to the Migration Period. The research project is a significant step towards better understanding and protecting marine ecosystems.
Published Bartonella DNA Found in Blood of Patients With Psychosis



A new study has found that patients diagnosed with schizophrenia or another psychotic disorder are three times more likely to have Bartonella DNA in their blood than adults without these disorders. The work further supports the idea that pathogens -- particularly vector-borne pathogens -- could play a role in mental illness.
Published Elephants have names for each other like people do, new study shows



Wild African elephants address each other with name-like calls, a rare ability among nonhuman animals, according to a new study. Researchers used machine learning to confirm that elephant calls contained a name-like component identifying the intended recipient, a behavior they suspected based on observation. The study suggests elephants do not imitate the receiver's call to address one another but instead use arbitrary vocal labels like humans.
Published A protein that enables smell--and stops cell death



While smell plays a considerable role in the social interactions of humans -- for instance, signaling fear or generating closeness -- for ants, it is vitally important. Researchers have found that a key protein named Orco, essential for the function of olfactory cells, is also critical for the cells' survival in ants.
Published Changes Upstream: RIPE team uses CRISPR/Cas9 to alter photosynthesis for the first time



Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.
Published Fat molecule's inability to bond with shape-shifting protein in cell's powerhouse linked to an inherited metabolic disease



By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.