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Categories: Biology: Biochemistry, Chemistry: Biochemistry
Published Sweet move: a modified sugar enhances antisense oligonucleotide safety and efficacy
(via sciencedaily.com) Original source Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.
Published Australian study proves 'humans are planet's most frightening predator'
(via sciencedaily.com) Original source A new study demonstrates that kangaroos, wallabies and other Australian marsupials fear humans far more than any other predator.
Published Researchers design new metal-free porous framework materials
(via sciencedaily.com) Original source Researchers have used computational design methods to develop non-metal organic porous framework materials, with potential applications in areas such as catalysis, water capture or hydrogen storage.
Published How the 'home' environment influences microbial interactions
(via sciencedaily.com) Original source A new study shows that real-world ocean conditions make a huge difference in how viral infection affects host bacteria. The findings indicate it is very important to study cells and virocells under nutrient conditions that more closely resemble what they encounter in nature.
Published Adhesive coatings can prevent scarring around medical implants
(via sciencedaily.com) Original source Engineers have found a way to eliminate the buildup of scar tissue around implantable devices, by coating them with a hydrogel adhesive. The material binds the device to tissue and prevents the immune system from attacking the device.
Published Promethium bound: Rare earth element's secrets exposed
(via sciencedaily.com) Original source Scientists have uncovered the properties of a rare earth element that was first discovered 80 years ago at the very same laboratory, opening a new pathway for the exploration of elements critical in modern technology, from medicine to space travel.
Published New AI accurately predicts fly behavior
(via sciencedaily.com) Original source Researchers trained an AI model to accurately predict male fruit flies' courtship behavior in response to any sight of a female. This breakthrough offers new insight into how the brain processes visual data and may someday pave the way for artificial vision technology.
Published Scientists develop new battery-free lactic acid sensor
(via sciencedaily.com) Original source Scientists have created a new type of chemosensor (demonstrated for lactic acid sensing) which functions with electricity but without the need for reference electrodes or battery power.
Published Roots are a key to drought-tolerant maize
(via sciencedaily.com) Original source Maize can grow successfully in very different local conditions. An international study has now demonstrated the important role of the plant root system. The researchers analyzed more than 9,000 varieties in the study and were able to show that their roots varied considerably -- depending on how dry the location is where each variety was cultivated. They were also able to identify an important gene that plays a role in the plant's ability to adapt. This gene could be the key to developing varieties of maize that cope better with climate change.
Published Cuddled cows who work as therapy animals showed a strong preference for women compared to men, study finds
(via sciencedaily.com) Original source A new study reveals that cows who are cuddled as therapy animals showed a strong preference for interactions with women when compared to men. In turn, the research, which opens a new era on whether some therapies may be initially stronger based upon gender and not procedure, highlighted that the women also reported greater attachment behaviors towards the steers.
Published Flexible film senses nearby movements -- featured in blink-tracking glasses
(via sciencedaily.com) Original source I'm not touching you! When another person's finger hovers over your skin, you may get the sense that they're touching you, feeling not necessarily contact, but their proximity. Similarly, researchers have designed a soft, flexible film that senses the presence of nearby objects without physically touching them. The study features the new sensor technology to detect eyelash proximity in blink-tracking glasses.
Published Naturally occurring substance in pomegranates can improve treatment of Alzheimer's disease
(via sciencedaily.com) Original source A substance naturally occurring in i.a. pomegranates, strawberries and walnuts can improve memory and treatment of Alzheimer's disease, a new study concludes.
Published New insights into the degradation dynamics of organic material in the seafloor
(via sciencedaily.com) Original source Many processes in the deep sea are not yet well understood, and the role of microbial communities in particular is often a big unknown. This includes, for example, how organic material that sinks from the water surface to the ocean floor is metabolised -- an important building block for a better understanding of the global carbon cycle.
Published Ethylene from CO2: Building-kit catalyst
(via sciencedaily.com) Original source Use of the greenhouse gas CO2 as a chemical raw material would not only reduce emissions, but also the consumption of fossil feedstocks. A novel metal-free organic framework could make it possible to electrocatalytically produce ethylene, a primary chemical raw material, from CO2. Nitrogen atoms with a particular electron configuration play a critical role for the catalyst.
Published Study finds widespread 'cell cannibalism,' related phenomena across tree of life
(via sciencedaily.com) Original source Researchers describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another. The study shows that cases of this behavior, including cell cannibalism, are widespread across the tree of life. The findings challenge the common perception that cell-in-cell events are largely restricted to cancer cells. Rather, these events appear to be common across diverse organisms, from single-celled amoebas to complex multicellular animals.
Published Conservation of nature's strongholds needed to halt biodiversity loss
(via sciencedaily.com) Original source To achieve global biodiversity targets, conservationists and governments must prioritize the establishment and effective management of large, interconnected protected areas with high ecological integrity, researchers argue in a new essay.
Published Body lice may be bigger plague spreaders than previously thought
(via sciencedaily.com) Original source A new laboratory study suggests that human body lice are more efficient at transmitting Yersinia pestis, the bacterium that causes plague, than previously thought, supporting the possibility that they may have contributed to past pandemics.
Published Detecting odors on the edge: Researchers decipher how insects smell more with less
(via sciencedaily.com) Original source While humans feature a sophisticated sense of smell, insects have a much more basic olfactory system. Yet they depend upon smell to survive. Scientists have figured out how fruit flies use a simple but efficient system to recognize odors, and the answer lies at the edges of their antennae.
Published Drug-like inhibitor shows promise in preventing flu
(via sciencedaily.com) Original source Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.
Published Batteries: Modeling tomorrow's materials today
(via sciencedaily.com) Original source Which factors determine how quickly a battery can be charged? Microstructural models have helped researchers discover and investigate new electrode materials. When sodium-nickel-manganese oxide is used as cathode material in sodium-ion batteries, simulations reveal modifications of the crystal structure during charging. These modifications lead to an elastic deformation, as a result of which capacity decreases.