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Categories: Biology: Biochemistry

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A team of researchers has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats.

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The soils of northern forests are key reservoirs that help keep the carbon dioxide that trees inhale and use for photosynthesis from making it back into the atmosphere.

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Bioengineers have harnessed the lotus effect to develop a system for culturing cancer cell clusters that can shed light on hard-to-study tumor properties. The new zinc oxide-based culturing surface mimics the lotus leaf surface structure, providing a highly tunable platform for the high-throughput generation of three-dimensional nanoscale tumor models.

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The elimination of damaged cell components is essential for the maintenance of the body's tissues and organs. An international research team has made significant findings on mechanisms for the clearing of cellular wastes, showing that strength training activates such mechanisms. The findings could form the basis for new therapies for heart failure and nerve diseases, and even afford benefits for manned space missions.

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A new study has used a series of innovative field experiments to show how plants combine circadian clock signals with environmental cues under naturally fluctuating conditions.

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Primate ornamentation plays a crucial role in communication not only within social groups but also between them, according to a new study. The research reveals that the males of species with overlapping home ranges often display vibrant colors or elaborate features, traits that may help reduce intergroup aggression by enabling quick assessments of potential rivals.

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While a mosquito bite is often no more than a temporary bother, in many parts of the world it can be scary. One mosquito species, Aedes aegypti, spreads the viruses that cause over 100,000,000 cases of dengue, yellow fever, Zika and other diseases every year. Another, Anopheles gambiae, spreads the parasite that causes malaria. The World Health Organization estimates that malaria alone causes more than 400,000 deaths every year. Indeed, their capacity to transmit disease has earned mosquitoes the title of deadliest animal.

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Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists have developed a technique that speeds up screening of individual DNA molecules at least a thousand times. With this technology, they can measure millions of DNA molecules within a week instead of years to decades.

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Mono Lake is a beautiful but harsh environment, its salty and arsenic-laced water home to brine shrimp, alkali flies and little else. Scientists recently discovered an unsuspected resident, however, a microscopic creature -- a choanoflagelatte -- that forms colonies that harbor their own unique bacterial microbiomes. The creature, part of the sister group to all animals, could shed light on the evolution of animals' intimate interactions with bacteria and the rise of multicellular life.

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Managing hard-to-treat respiratory illnesses like asthma and pulmonary fibrosis just got easier if a new drug-carrying molecule is as sneaky as its inventors think.

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Research reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated independently. This surprising connection opens up new possibilities for the treatment of various diseases. A mouse model shows that no immunosuppressive drugs are needed after an organ transplantation if this interaction between T cells and the innate immunity is temporarily blocked after the transplantation.

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How do rabbits go from fluffy pets to marauding invaders? Rabbits have colonized countries worldwide, often with dire economic and ecological consequences, but their secret has until now been a mystery. Biologists sequenced the genomes of nearly 300 rabbits from across three continents to unveil the key genetic changes that make these animals master colonizers.

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In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the more slowly it loses fat. Now, scientists have discovered why: a small molecule produced by the worms' intestines during fasting travels to the brain to block a fat-burning signal during this time.

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When you get infected with a virus, some of the first weapons your body deploys to fight it were passed down to us from our microbial ancestors billions of years ago. According to new research, two key elements of our innate immune system came from a group of microbes called Asgard archaea.

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New research shows that rainwater could have helped create a meshy wall around protocells 3.8 billion years ago, a critical step in the transition from tiny beads of RNA to every bacterium, plant, animal, and human that ever lived.

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When giant ragweed takes hold in a crop field, the towering weed reduces yield and sends plumes of its famously allergy-inducing pollen into the air. There are few tools available to thwart the menace, especially for farmers growing non-GMO soybeans. Now, some Wisconsin farmers are left with even fewer options.

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Honey bees may play a role in increasing virus levels in wild bumble bees each spring, according to researchers who analyzed seasonal trends of parasite and virus transmission in bees.

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Human-wildlife overlap could increase across about 57% of the global lands by 2070 and could lead to more conflict between people and animals. Understanding where the overlap is likely to occur -- and which animals are likely to interact with humans in specific areas -- will be crucial information for urban planners, conservationists and countries that have pledged international conservation commitments.

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Archeologists say new findings might help resolve the debate about Clovis points and reshape how we think about what life was like roughly 13,000 years ago. After an extensive review of writings and artwork -- and an experiment with replica Clovis point spears -- a team of archaeologists says humans may have braced the butt of their weapons against the ground in a way that would impale a charging animal. The force would have driven the spear deeper into the predator's body, unleashing a more damaging blow than even the strongest prehistoric hunters would have been capable of by throwing or jabbing megafauna.

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Researchers warn the animals we eat could be the gateway for a pandemic in the form of antimicrobial resistance, unleashing a wave of deadly superbugs. The World Health Organization estimates that drug-resistant diseases could cause up to 10 million deaths each year by 2050.