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Categories: Biology: Biotechnology, Chemistry: Organic Chemistry
Published Researchers show promising material for solar energy gets its curious boost from entropy
(via sciencedaily.com) Original source Researchers discovered a microscopic mechanism that solves in part the outstanding performance achieved by a new class of organic semiconductors known as non-fullerene acceptors (NFAs).
Published New one-step method to make multiple edits to a cell's genome
(via sciencedaily.com) Original source A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.
Published Chemistry inspired by one-pot cooking
(via sciencedaily.com) Original source Is it possible to create a new class of materials from very different substances using the 'one-pot synthesis' approach? Chemists explain how they enable the synthesis of such novel materials.
Published Ancient dingo DNA shows modern dingoes share little ancestry with modern dog breeds
(via sciencedaily.com) Original source A study of ancient dingo DNA revealed that the distribution of modern dingoes across Australia, including those on K'gari (formerly Fraser Island), pre-dates European colonization and interventions like the dingo-proof fence.
Published New bio-based tool quickly detects concerning coronavirus variants
(via sciencedaily.com) Original source Researchers have developed a bioelectric device that can detect and classify new variants of coronavirus to identify those that are most harmful. It has the potential to do the same with other viruses, as well.
Published Hexagonal perovskite oxides: Electrolytes for next-generation protonic ceramic fuel cells
(via sciencedaily.com) Original source Researchers have identified hexagonal perovskite-related oxides as materials with exceptionally high proton conductivity and thermal stability. Their unique crystal structure and large number of oxygen vacancies enable full hydration and high proton diffusion, making these materials ideal candidates as electrolytes for next-generation protonic ceramic fuel cells that can operate at intermediate temperatures without degradation.
Published Genomic data integration improves prediction accuracy of apple fruit traits
(via sciencedaily.com) Original source Genotyping techniques can be used to select fruit trees with desired traits at the seedling stage, increasing the efficiency of fruit tree breeding. However, so far, there are multiple different genotyping systems, each generating distinct datasets. In a recent study, Japanese scientists revealed that integrating genomic data obtained with different genotyping systems can effectively combine with historical data, leveraging the accuracy of genomic predictions.
Published Visualizing short-lived intermediate compounds produced during chemical reactions
(via sciencedaily.com) Original source Immobilizing small synthetic molecules inside protein crystals proves to be a promising avenue for studying intermediate compounds formed during chemical reactions, scientists report. By integrating this method with time-resolved serial femtosecond crystallography, they successfully visualized reaction dynamics and rapid structural changes occurring within reaction centers immobilized inside protein crystals. This innovative strategy holds significant potential for the intelligent design of drugs, catalysts, and functional materials.
Published GeneMAP discovery platform will help define functions for 'orphan' metabolic proteins
(via sciencedaily.com) Original source Researchers have developed a discovery platform to probe the function of genes involved in metabolism -- the sum of all life-sustaining chemical reactions. The investigators used the new platform, called GeneMAP (Gene-Metabolite Association Prediction), to identify a gene necessary for mitochondrial choline transport.
Published Not so selfish after all: Viruses use freeloading genes as weapons
(via sciencedaily.com) Original source Certain pieces of DNA have been labeled as 'selfish genetic elements' due to notions that they don't contribute to a host organism's survival. Instead, researchers have now discovered that these elements have been weaponized and play a crucial role by cutting off a competitor's ability to reproduce.
Published New organic molecule shatters phosphorescence efficiency records and paves way for rare metal-free applications
(via sciencedaily.com) Original source A team has discovered that the new organic molecule thienyl diketone exhibits high-efficiency phosphorescence, achieving a rate over ten times faster than traditional materials. This breakthrough provides new guidelines for developing rare metal-free organic phosphorescent materials, promising advancements in applications like organic EL displays, lighting, and cancer diagnostics.
Published Never-before-seen view of gene transcription captured
(via sciencedaily.com) Original source New tech reveals findings that address long-standing theories about how bacteria begin the process of making RNA from DNA.
Published Do genes-in-pieces code for proteins that fold in pieces?
(via sciencedaily.com) Original source A new study offers new insights into the evolution of foldable proteins.
Published Researchers uncover key mechanisms in chromosome structure development
(via sciencedaily.com) Original source Researchers are making strides in understanding how chromosome structures change throughout the cell's life cycle.
Published Chemists synthesize an improved building block for medicines
(via sciencedaily.com) Original source Research could help drug developers improve the safety profiles of medications and reduce side effects.
Published Using visible light to make pharmaceutical building blocks
(via sciencedaily.com) Original source Chemists have discovered a way to use visible light to synthesize a class of compounds particularly well suited for use in pharmaceuticals. The class of compounds, called azetidines, had been previously identified as a good candidate to build therapeutic drugs, but the compounds are difficult to produce in chemical reactions. Now, a team has developed a method to produce a specific class of azetidines called monocyclic azetidines using visible light and a photocatalyst.
Published A new breakthrough in understanding regeneration in a marine worm
(via sciencedaily.com) Original source The sea worm Platynereis dumerilii is only a few centimeters long but has a remarkable ability: in just a few days, it can regenerate entire parts of its body after an injury or amputation. By focusing more specifically on the mechanisms at play in the regeneration of this worm's tail, a research team has observed that gut cells play a role in the regeneration of the intestine as well as other tissues such as muscle and epidermis.
Published Near chromosome-level genome of the Mojave poppy bee
(via sciencedaily.com) Original source Scientists have developed a near chromosome-level genome for the Mojave poppy bee, a specialist pollinator of conservation concern.
Published Research shows how RNA 'junk' controls our genes
(via sciencedaily.com) Original source Researchers have made a significant advance in understanding how genes are controlled in living organisms. The new study focuses on critical snippets of RNA in the tiny, transparent roundworm Caenorhabditis elegans (C. elegans). The study provides a detailed map of the 3'UTR regions of RNA in C. elegans. 3'UTRs (untranslated regions) are segments of RNA involved in gene regulation.
Published Proteins and fats can drive insulin production for some, paving way for tailored nutrition
(via sciencedaily.com) Original source When it comes to managing blood sugar levels, most people think about counting carbs. But new research shows that, for some, it may be just as important to consider the proteins and fats in their diet. The study is the first large-scale comparison of how different people produce insulin in response to each of the three macronutrients: carbohydrates (glucose), proteins (amino acids) and fats (fatty acids). The findings reveal that production of the blood sugar-regulating hormone is much more dynamic and individualized than previously thought, while showing for the first time a subset of the population who are hyper-responsive to fatty foods.