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Categories: Biology: Biotechnology, Chemistry: Organic Chemistry
Published Rewriting the armadillo family tree: A new species, plus a name change for the state mammal of Texas



The nine-banded armadillo, which ranges all the way from Argentina to Nebraska, is actually four separate species. One of the species, the Guianan long-nosed armadillo, is new to science. Meanwhile, the species that has migrated from Mexico to the United States (and is the official small mammal of Texas) is now called the Mexican long-nosed armadillo.
Published Zebrafish reveal how bioelectricity shapes muscle development



New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.
Published Discovery of vast sex differences in cellular activity has major implications for disease treatment



The study reveals vast differences in gene activity within the mitochondria of males compared to females. This is the first study to test effects of all 37 genes in the mitochondrial genome -- genes that copepods and humans share. The study found that males demonstrate more activity across all protein-coding mitochondrial genes than females. Although the study looks at tiny marine organisms called copepods, the findings have weighty implications for human medicine.
Published Researchers develop RNA-targeting technology for precisely manipulating parts of human genes



Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, including systematically interrogating the functions of parts of genes and correcting splicing deficiencies that underlie numerous diseases and disorders.
Published Removal of excess chloride ions by plants when subjected to salt stress



Researchers have discovered a salt adaptation mechanism in plants that facilitates chloride removal from the roots and enhancing salinity tolerance. A research team has uncovered a novel mechanism of plant adaptation to salt stress involving the NaCl-induced translocation of a specific chloride channel protein, AtCLCf.
Published How cells boost gene expression



The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities. A research team has now discovered an important function of antisense RNA (asRNA): the researchers found that asRNA acts as a 'superhighway' in cell transport and thus accelerates gene expression.
Published Membrane protein analogues could accelerate drug discovery



Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these proteins from cell membranes.
Published How to make aging a 'fairer game' for all wormkind



Researchers have discovered a new fundamental mechanism governing the rules of ageing in worms. The researchers were able to manipulate the mechanism through genetic interventions which dramatically extend not just the lifespan of the worms, but also their health-span. In other words, trading weak, frail old age with vigorous golden years -- all without altering their diet, environment or other external factors.
Published Mirror-image chemicals may revolutionize drug delivery



More than 130 years after cyclodextrins were first discovered and reported, a team of scientists has created chemical mirror images of these complex carbohydrates in the laboratory. This discovery may revolutionize how medications are delivered to patients.
Published Odors are encoded in rings in the brain of migratory locusts



Researchers describe how odors are encoded in the antennal lobe, the olfactory center in the brain of migratory locusts. Using transgenic locusts and imaging techniques, the researchers were able to show a ring-shaped representation of odors in the brain. The pattern of olfactory coding in the antennal lobe is the same at all stages of locust development. A better understanding of olfactory coding in the locust brain should help to learn more about how the behavior of these insects is controlled, especially their swarming.
Published Where to put head and tail?



Formation of the body axes is a critical part of embryonic development. They guarantee that all body parts end up where they belong and that no ears grow on our backs. The head-tail axis, for example, determines the orientation of the two ends of the body. It was previously assumed that this axis is largely determined by the interplay between the Nodal and BMP signals. However, there appears to be another player in this system, as researchers have now discovered by using an embryo-like model system they developed. In the absence of BMP, the signalling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible solution for axis formation in embryos with different shapes.
Published New material puts eco-friendly methanol conversion within reach



Researchers have developed innovative, eco-friendly quantum materials that can drive the transformation of methanol into ethylene glycol. This discovery opens up new possibilities for using eco-friendly materials in photocatalysis, paving the way for sustainable chemical production.
Published Custom-made molecules designed to be invisible while absorbing near-infrared light



Researchers used theoretical calculations assessing electron orbital symmetry to synthesize new molecule designed to be both transparent and colorless while absorbing near-infrared light. This compound demonstrates the first systematic approach to producing such materials and have applications in advanced electronics. This compound also shows semiconducting properties.
Published Golden ball mills as green catalysts



A gold-coated milling vessel for ball mills proved to be a real marvel: without any solvents or environmentally harmful chemicals, the team was able to use it to convert alcohols into aldehydes. The catalytic reaction takes place at the gold surface and is mechanically driven. The vessel can be reused multiple times. 'This opens up new prospects for the use of gold in catalysis and shows how traditional materials can contribute to solving modern environmental problems in an innovative way,' says Borchardt.
Published Molecular sponge for the electronics of the future



An international research team has succeeded in developing a new type of material in the rather young research field of covalent organic frameworks. The new two-dimensional polymer is characterized by the fact that its properties can be controlled in a targeted and reversible manner. This has brought the researchers a step closer to the goal of realizing switchable quantum states.
Published Reduction of esters by a novel photocatalyst



A ubiquitous compound, called ester can be broken down to produce desirable alcohols and other chemicals for use across industries including pharmaceuticals and cosmetics, but the process can be costly, both financially and in terms of the environment. Researchers developed a novel photocatalyst 'N-BAP.' When irradiated with blue light, the photocatalyst reduces esters in the presence of oxalate, a negatively charged molecule found widely in nature, resulting in the desired alcohols.
Published Vitamin B6: New compound delays degradation



A low vitamin B6 level has negative effects on brain performance. A research team has now found a way to delay the degradation of the vitamin.
Published The genetic 'switches' of bone growth



In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone. They are controlled by other sequences in the genome, called enhancers, which, like switches, activate or deactivate them as required. A team has now identified and located 2700 enhancers -- among millions of non-coding genetic sequences -- that precisely regulate the genes responsible for bone growth. This discovery sheds light on one of the major factors influencing the size of individuals in adulthood, and explains why their failure could be the cause of certain bone malformations.
Published Self-assembling and disassembling swarm molecular robots via DNA molecular controller



Researchers have succeeded in developing a DNA-based molecular controller. Crucially, this controller enables the autonomous assembly and disassembly of molecular robots, as opposed to manually directing it.
Published Scientists preserve DNA in an amber-like polymer



With their 'T-REX' method, researchers developed a glassy, amber-like polymer that can be used for long-term storage of DNA, such as entire human genomes or digital files such as photos.