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Categories: Biology: Biotechnology, Chemistry: Organic Chemistry
Published Bone loss drugs can help azoles fight fungal infections
(via sciencedaily.com) Original source A new study suggests that adding common bone loss drugs to azoles can improve efficacy when treating fungal infections.
Published New method of DNA testing: Expanding scientific innovation
(via sciencedaily.com) Original source A team of researchers has developed a new method for target DNA sequence amplification, testing and analysis.
Published Electrified charcoal 'sponge' can soak up CO2 directly from the air
(via sciencedaily.com) Original source Researchers have developed a low-cost, energy-efficient method for making materials that can capture carbon dioxide directly from the air. Researchers used a method similar to charging a battery to instead charge activated charcoal, which is often used in household water filters.
Published New technique reveals how gene transcription is coordinated in cells
(via sciencedaily.com) Original source Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.
Published Father's diet before conception influences children's health
(via sciencedaily.com) Original source A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.
Published Giant viruses found on Greenland ice sheet
(via sciencedaily.com) Original source Giant viruses found on the Greenland ice sheet probably regulate the growth of snow algae on the ice by infecting them. Knowing how to control these viruses could help us reduce the rate of ice-melt.
Published The embryo assembles itself
(via sciencedaily.com) Original source Biological processes depend on puzzle pieces coming together and interacting. Under specific conditions, these interactions can create something new without external input. This is called self-organization, as seen in a school of fish or a flock of birds. Interestingly, the mammalian embryo develops similarly. Scientists now introduce a mathematical framework that analyzes self-organization from a single cell to a multicellular organism.
Published Paving the way for hydrogen from algae enzymes
(via sciencedaily.com) Original source Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is only possible if certain cofactors of the relevant proteins are present. Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in the final steps of assembly.
Published Researchers discover 'trojan horse' virus hiding in human parasite
(via sciencedaily.com) Original source An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.
Published Trout in mine-polluted rivers are genetically 'isolated'
(via sciencedaily.com) Original source Trout living in rivers polluted by metal from old mines across the British Isles are genetically 'isolated' from other trout, new research shows.
Published Scientists develop most sensitive way to observe single molecules
(via sciencedaily.com) Original source A technical achievement marks a significant advance in the burgeoning field of observing individual molecules without the aid of fluorescent labels. While these labels are useful in many applications, they alter molecules in ways that can obscure how they naturally interact with one another. The new label-free method makes the molecules so easy to detect, it is almost as if they had labels.
Published New, modified CRISPR protein can fit inside virus used for gene therapy
(via sciencedaily.com) Original source Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.
Published New method makes hydrogen from solar power and agricultural waste
(via sciencedaily.com) Original source Engineers have helped design a new method to make hydrogen gas from water using only solar power and agricultural waste such as manure or husks. The method reduces the energy needed to extract hydrogen from water by 600%, creating new opportunities for sustainable, climate-friendly chemical production.
Published Researchers expose new symbiosis origin theories, identify experimental systems for plant life
(via sciencedaily.com) Original source Research work on symbiosis -- a mutually beneficial relationship between living organisms -- is pushing back against the newer theory of a 'single-origin' of root nodule symbiosis (RNS) -- that all symbiosis between plant root nodules and nitrogen-fixing bacteria stems from one point--instead suggesting a 'multiple-origin' theory of sybiosis which opens a better understanding for genetically engineering crops.
Published Researchers apply quantum computing methods to protein structure prediction
(via sciencedaily.com) Original source Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction.
Published hnRNPM, a guardian of the integrity of cellular protein production
(via sciencedaily.com) Original source Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.
Published Editing without 'cutting': Molecular mechanisms of new gene-editing tool revealed
(via sciencedaily.com) Original source New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.
Published Chicken feathers to deliver chemotherapy drugs and repair enzymes
(via sciencedaily.com) Original source A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.
Published New antibiotic kills pathogenic bacteria, spares healthy gut microbes
(via sciencedaily.com) Original source Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.
Published Researchers create materials with unique combo of stiffness, thermal insulation
(via sciencedaily.com) Original source Researchers have demonstrated the ability to engineer materials that are both stiff and capable of insulating against heat. This combination of properties is extremely unusual and holds promise for a range of applications, such as the development of new thermal insulation coatings for electronic devices.