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Categories: Biology: Biotechnology, Chemistry: Organic Chemistry

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The widely used dry-cleaning and degreasing solvent perc can be converted to useful chemicals by a new clean, safe and inexpensive procedure. The discovery using on-demand UV activation may open the path to upcycling perc and thus contribute to a more sustainable society.

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New research has revealed how light can be used to destroy infectious coronavirus particles that contaminate surfaces. Scientists are interested in how environments, such as surgeries, can be thoroughly disinfected from viruses such as SARS-CoV-2 that caused the COVID-19 pandemic.

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The genomic analysis of 52 Psilocybe specimens includes 39 species that have never been sequenced. Psilocybe arose much earlier than previously thought -- about 65 million years ago -- and the authors found that psilocybin was first synthesized in mushrooms in the genus Psilocybe. Their analysis revealed two distinct gene orders within the gene cluster that produces psilocybin. The two gene patterns correspond to an ancient split in the genus, suggesting two independent acquisitions of psilocybin in its evolutionary history. The study is the first to reveal such a strong evolutionary pattern within the gene sequences underpinning the psychoactive proteins synthesis.

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A new discovery takes its inspiration from Greek mythology. The compound is described as a chimera, because it battles a toxic cause of Parkinson's in two ways.

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With DNA recovered from animal tracks, scientists revealed information about the ancestry and microbial community of bobcats without having to sample the animal directly.

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Chemists have presented a new approach in which a single carbon atom is inserted into the carbon skeleton of cyclic compounds in order to adjust the ring size. The method could be relevant, for example, for the production of active ingredients in new pharmaceutical products.

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An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.

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Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.

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A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.

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Researchers have discovered a molecular 'barcode' system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.

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Researchers have developed a new AI-powered algorithm to help understand how different cells organize themselves into particular tissues and communicate with one another.

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Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, a soluble protein outside the bacterium transports the substance to the 'elevator' and unloads its cargo there. The freight elevator transports it to the inside of the cell, in other words to another floor.

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A groundbreaking study has found that evolution is not as unpredictable as previously thought, which could allow scientists to explore which genes could be useful to tackle real-world issues such as antibiotic resistance, disease and climate change. The study challenges the long-standing belief about the unpredictability of evolution, and has found that the evolutionary trajectory of a genome may be influenced by its evolutionary history, rather than determined by numerous factors and historical accidents.

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Hydrogen energy has emerged as a promising alternative to fossil fuels, offering a clean and sustainable energy source. However, the development of low-cost and efficient catalysts for hydrogen evolution reaction remains a crucial challenge. Scientists have recently developed a novel strategy to engineer stable and efficient ultrathin nanosheet catalysts by forming Turing structures with multiple nanotwin crystals. This innovative discovery paves the way for enhanced catalyst performance for green hydrogen production.

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Creating a functional lung using interspecies chimeric animals is an attractive albeit challenging option for lung transplantation, requiring more research on the viable conditions needed for organ generation. A new study uses reverse-blastocyst complementation and tetraploid-based organ complementation methods to first determine these conditions in lung-deficient mice and then to generate rat-derived lungs in these mice. It provides useful insights on the intrinsic species-specific barriers and factors associated with lung development in interspecies chimeric animals.

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Scientists have created analogs of the antibiotic spectinomycin that are significantly more effective against these highly resistant bacteria.

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With a split-second muscle contraction, the greater blue-ringed octopus can change the size and color of the namesake patterns on its skin for purposes of deception, camouflage and signaling. Researchers have drawn inspiration from this natural wonder to develop a technological platform with similar capabilities for use in a variety of fields, including the military, medicine, robotics and sustainable energy.

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Engineers have succeeded in implementing a stretchable organic solar cell by applying a newly developed polymer material that demonstrated the world's highest photovoltaic conversion efficiency (19%) while functioning even when stretched for more than 40% of its original state. This new conductive polymer has high photovoltaic properties that can be stretched like rubber. The newly developed polymer is expected to play a role as a power source for next-generation wearable electronic devices.

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Scientists have engineered the microbiome of plants for the first time, boosting the prevalence of 'good' bacteria that protect the plant from disease. The findings could substantially reduce the need for environmentally destructive pesticides.

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A research team has detected various substances that have a dual effect against tuberculosis: They make the bacteria causing the disease less pathogenic for human immune cells and boost the activity of conventional antibiotics.