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Categories: Biology: Biotechnology, Chemistry: Organic Chemistry
Published New insights revealed on tissue-dependent roles of JAK signaling in inflammation
(via sciencedaily.com) Original source Researchers have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.
Published Blue PHOLEDs: Final color of efficient OLEDs finally viable in lighting
(via sciencedaily.com) Original source Lights could soon use the full color suite of perfectly efficient organic light-emitting diodes, or OLEDs, that last tens of thousands of hours. The new phosphorescent OLEDs, commonly referred to as PHOLEDs, can maintain 90% of the blue light intensity for 10-14 times longer than other designs that emit similar deep blue colors. That kind of lifespan could finally make blue PHOLEDs hardy enough to be commercially viable in lights that meet the Department of Energy's 50,000-hour lifetime target. Without a stable blue PHOLED, OLED lights need to use less-efficient technology to create white light.
Published How researchers are 'CReATiNG' synthetic chromosomes faster and cheaper
(via sciencedaily.com) Original source A new technique to clone and reassemble DNA, dubbed CReATiNG, could simplify and lower the cost to make synthetic chromosomes. Potential applications are numerous, including pharmaceutical production, biofuel generation, cancer therapies, and environmental cleanup using modified organisms. The method adds a powerful, versatile tool to the burgeoning field of synthetic biology.
Published Discovery: Plants use 'Trojan horse' to fight mold invasions
(via sciencedaily.com) Original source Scientists have discovered that plants send tiny, innocuous-seeming lipid 'bubbles' filled with RNA across enemy lines, into the cells of the aggressive mold. Once inside, different types of RNA come out to suppress the infectious cells that sucked them in.
Published A trillion scents, one nose
(via sciencedaily.com) Original source A research team has uncovered a previously undetected mechanism in mice -- starring the genetic molecule RNA -- that could explain how each sensory cell, or neuron, in mammalian noses becomes tailored to detect a specific odor chemical.
Published Cells of the future: A key to reprogramming cell identities
(via sciencedaily.com) Original source The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time. Scientists have recently uncovered a fascinating aspect of this process known as 'replication timing' (RT) and how special this is when life commences.
Published Multitasking microbes: Scientists engineer bacteria to make two valuable products from plant fiber
(via sciencedaily.com) Original source Researchers have engineered bacteria that can produce two chemical products at the same time from underutilized plant fiber. And unlike humans, these multitasking microbes can do both things equally well. The discovery could help make biofuels more sustainable and commercially viable.
Published New study examines the relationship between the rate of wound healing, the circadian rhythm, and 'hair' on cells
(via sciencedaily.com) Original source Nearly every organism on Earth follows a natural circadian rhythm that is coded by your cell's clock genes, which do exactly as you suspect from the name: regulate your body's rhythm on a 24-hour basis. Most cells in mammalian bodies have cilia of some sort, which are hair-like structures that perform a variety of functions such as movement for motile cilia and aiding in structure in function for non-motile, or primary, cilia. The primary cilia also act as a sensory organ for the cell, a function which has illuminated the primary cilia's potential role in the healing process and how bodies heal at a different rate according to our circadian rhythm. In this research, the role of the primary cilia, biological clock and wound healing is explored.
Published New strategy reveals 'full chemical complexity' of quantum decoherence
(via sciencedaily.com) Original source Scientists have developed a method to extract the spectral density for molecules in solvent using simple resonance Raman experiments -- a method that captures the full complexity of chemical environments.
Published Protein allows poison dart frogs to accumulate toxins safely
(via sciencedaily.com) Original source A newly identified protein helps poison dart frogs accumulate and store a potent toxin in their skin which they use for self-defence against predators.
Published Unveiling molecular origami: A breakthrough in dynamic materials
(via sciencedaily.com) Original source A research team has unveiled a remarkable breakthrough in the form of a two-dimensional (2D) Metal Organic Framework (MOF) that showcases unprecedented origami-like movement at the molecular level. This pioneering study represents a significant leap forward in the field of dynamic materials, while also hinting at futuristic applications in metamaterials and quantum computing.
Published Genetics of host plants determine what microorganisms they attract
(via sciencedaily.com) Original source Plants often develop communities with microorganisms in their roots, which influences plant health and development. Although the recruitment of these microbes is dictated by several factors, it is unclear whether the genetic variation in the host plants plays a role.
Published First observation of how water molecules move near a metal electrode
(via sciencedaily.com) Original source A collaborative team of experimental and computational physical chemists has made an important discovery in the field of electrochemistry, shedding light on the movement of water molecules near metal electrodes. This research holds profound implications for the advancement of next-generation batteries utilizing aqueous electrolytes.
Published For this emergent class of materials, 'solutions are the problem'
(via sciencedaily.com) Original source Materials scientists developed a fast, low-cost, scalable method to make covalent organic frameworks (COFs), a class of crystalline polymers whose tunable molecular structure, large surface area and porosity could be useful in energy applications, semiconductor devices, sensors, filtration systems and drug delivery.
Published Scientists collect aardvark poop to understand how the species is impacted by climate in Africa
(via sciencedaily.com) Original source In a new study of aardvarks, researchers spent months in sub-Saharan Africa collecting poop from the animal and concluded that aridification of the landscape is isolating them, which they say could have implications for their long-term survival.
Published New method Ebola virus uses to infect cells
(via sciencedaily.com) Original source Scientists recently published findings indicating that Ebola virus creates and uses intercellular tunnels to move from cell to cell and evade treatments.
Published Genetic atlas detailing early stages of zebrafish development
(via sciencedaily.com) Original source Researchers have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.
Published Acid sensor and calcium store discovered in plants
(via sciencedaily.com) Original source Using optogenetics, researchers have detected a new acid sensor in plant cells that is addressing a cell-internal calcium store.
Published Computational model captures the elusive transition states of chemical reactions
(via sciencedaily.com) Original source Researchers developed a way to quickly calculate the transition state structure of a chemical reaction, using machine-learning models.
Published Ancient DNA reveals how a chicken virus evolved to become more deadly
(via sciencedaily.com) Original source An international team of scientists led by geneticists and disease biologists has used ancient DNA to trace the evolution of Marek's Disease Virus (MDV). This global pathogen causes fatal infections in unvaccinated chickens and costs the poultry industry over $1 billion per year. The findings show how viruses evolve to become more virulent and could lead to the development of better ways to treat viral infections.