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Categories: Biology: Biotechnology, Chemistry: Thermodynamics
Published How human derived RNA fragments help the Hepatitis E virus
(via sciencedaily.com) Original source Why does Hepatitis E become chronic in some patients, and why do medications not work? To find out, an international research team led by scientists from Bochum observed a patient with chronic Hepatitis E infection over a year. Repeated sequencing of the virus RNA showed that the virus incorporated various parts of the host's messenger RNA into its genome. This resulted in a replication advantage, which may have contributed to the infection becoming chronic.
Published Lung organoids unveil secret: How pathogens infect human lung tissue
(via sciencedaily.com) Original source How do pathogens invade the lungs? Using human lung microtissues, a team has uncovered the strategy used by a dangerous pathogen. The bacterium targets specific lung cells and has developed a sophisticated strategy to break through the lungs' line of defense.
Published Novel Genetic Clock discovers oldest known marine plant
(via sciencedaily.com) Original source An international research team has discovered the oldest known marine plant using a novel genetic clock. This 1400-year-old seagrass clone from the Baltic Sea dates back to the Migration Period. The research project is a significant step towards better understanding and protecting marine ecosystems.
Published A protein that enables smell--and stops cell death
(via sciencedaily.com) Original source While smell plays a considerable role in the social interactions of humans -- for instance, signaling fear or generating closeness -- for ants, it is vitally important. Researchers have found that a key protein named Orco, essential for the function of olfactory cells, is also critical for the cells' survival in ants.
Published Changes Upstream: RIPE team uses CRISPR/Cas9 to alter photosynthesis for the first time
(via sciencedaily.com) Original source Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, this study, is an unbiased gene-editing approach to increase gene expression and downstream photosynthetic activity. The approach is more difficult than transgenic breeding, but could potentially preempt regulatory issues by changing DNA already within the plant, allowing the plants to get in the hands of farmers sooner.
Published Fat molecule's inability to bond with shape-shifting protein in cell's powerhouse linked to an inherited metabolic disease
(via sciencedaily.com) Original source By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.
Published Silkworms help grow better organ-like tissues in labs
(via sciencedaily.com) Original source Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.
Published Newly developed material logs and stores stress information of infrastructure
(via sciencedaily.com) Original source A new material may be the key to quickly flag damaged infrastructure. This material offers a way to reduce the manpower required to regularly monitor structures that undergo daily use such as bridges. Compared to previous methods, this environmentally friendly material boasts the ability to operate without a power supply, and store information about previous incidents of mechanical stress. The application of this mechanoluminescent material is expected to make it easier and less costly to assess the safety of structures we may use in our everyday lives.
Published Determining sex in ants
(via sciencedaily.com) Original source Researchers have been investigating the molecular mechanisms responsible for determining sex in ants. Although the vast majority of an ant colony consists of female workers, males are essential to the continuing survival of the species. In order to uncover the mechanisms involved, the researchers decided to focus on diploid males, which occasionally occur in the Argentine ant.
Published Pushing an information engine to its limits
(via sciencedaily.com) Original source The molecules that make up the matter around us are in constant motion. What if we could harness that energy and put it to use? Over 150 years ago Maxwell theorized that if molecules' motion could be measured accurately, this information could be used to power an engine. Until recently this was a thought experiment, but technological breakthroughs have made it possible to build working information engines in the lab. Researchers have now teamed up to build an information engine and test its limits.
Published Marsupials key to discovering the origin of heater organs in mammals
(via sciencedaily.com) Original source Around 100 million years ago, a remarkable evolutionary shift allowed placental mammals to diversify and conquer many cold regions of our planet. New research shows that the typical mammalian heater organ, brown fat, evolved exclusively in modern placental mammals. The research team demonstrated that marsupials, our distant relatives, possess a not fully evolved form of brown fat. They discovered that the pivotal heat-producing protein called UCP1 became active after the divergence of placental and marsupial mammals. This finding is crucial for understanding the role of brown fat in mammalian evolution, endothermy, and metabolism.
Published Universal bitter blocker could help patients take their medicines as prescribed
(via sciencedaily.com) Original source Strong bitterness is the main reason why people all over the world, especially children, avoid taking their medicines, putting their health, and sometimes, their lives at risk. Now, a group of scientists has identified the first temporary, universal taste blocker that works in people.
Published Bone loss drugs can help azoles fight fungal infections
(via sciencedaily.com) Original source A new study suggests that adding common bone loss drugs to azoles can improve efficacy when treating fungal infections.
Published New technique reveals how gene transcription is coordinated in cells
(via sciencedaily.com) Original source Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.
Published Father's diet before conception influences children's health
(via sciencedaily.com) Original source A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.
Published Giant viruses found on Greenland ice sheet
(via sciencedaily.com) Original source Giant viruses found on the Greenland ice sheet probably regulate the growth of snow algae on the ice by infecting them. Knowing how to control these viruses could help us reduce the rate of ice-melt.
Published The embryo assembles itself
(via sciencedaily.com) Original source Biological processes depend on puzzle pieces coming together and interacting. Under specific conditions, these interactions can create something new without external input. This is called self-organization, as seen in a school of fish or a flock of birds. Interestingly, the mammalian embryo develops similarly. Scientists now introduce a mathematical framework that analyzes self-organization from a single cell to a multicellular organism.
Published Overcoming barriers to heat pump adoption in cold climates and avoiding the 'energy poverty trap'
(via sciencedaily.com) Original source Converting home heating systems from natural gas furnaces to electric heat pumps is seen as a way to address climate change by reducing greenhouse gas emissions.
Published Researchers discover 'trojan horse' virus hiding in human parasite
(via sciencedaily.com) Original source An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.
Published Trout in mine-polluted rivers are genetically 'isolated'
(via sciencedaily.com) Original source Trout living in rivers polluted by metal from old mines across the British Isles are genetically 'isolated' from other trout, new research shows.