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Categories: Biology: Biotechnology, Chemistry: Thermodynamics
Published Researchers uncover human DNA repair by nuclear metamorphosis
(via sciencedaily.com) Original source Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.
Published Older males out-compete young males outside breeding pairs, bird study shows
(via sciencedaily.com) Original source Young male blue tits are less successful in fathering offspring outside their breeding pair, not because of a lack of experience, but because they are outcompeted by older males, researchers report.
Published Cooler transformers could help electric grid
(via sciencedaily.com) Original source Simulations on the Stampede2 supercomputer of the Texas Advanced Computing Center (TACC) are helping scientists engineer solutions to overheating of grid transformers -- a critical component of the electric grid.
Published Researchers advance pigment chemistry with moon-inspired reddish magentas
(via sciencedaily.com) Original source A researcher who made color history in 2009 with a vivid blue pigment has developed durable, reddish magentas inspired by lunar mineralogy and ancient Egyptian chemistry.
Published How tardigrades can survive intense radiation
(via sciencedaily.com) Original source Researchers have discovered that tardigrades -- microscopic animals famed for surviving harsh extremes -- have an unusual response to radiation.
Published How blue-green algae manipulate microorganisms
(via sciencedaily.com) Original source A research team discovers previously unknown gene that indirectly promotes photosynthesis Protein regulator NirP1 influences the coordination of the nitrogen and carbohydrate metabolism 'Such protein regulators could in future be deployed in 'green' and 'blue' biotechnology for targeted control of the metabolism,' says geneticist.
Published Unlocking the 'chain of worms'
(via sciencedaily.com) Original source An international team of scientists has published a single-cell atlas for Pristina leidyi (Pristina), the water nymph worm, a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.
Published Millions of gamers advance biomedical research
(via sciencedaily.com) Original source 4.5 million gamers around the world have advanced medical science by helping to reconstruct microbial evolutionary histories using a minigame included inside the critically and commercially successful video game, Borderlands 3. Their playing has led to a significantly refined estimate of the relationships of microbes in the human gut. The results of this collaboration will both substantially advance our knowledge of the microbiome and improve on the AI programs that will be used to carry out this work in future.
Published Researchers resolve old mystery of how phages disarm pathogenic bacteria
(via sciencedaily.com) Original source Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise. In response, scientists are elucidating the ways that bacteria-infecting viruses disarm these pathogens and ushering in the possibility of novel treatment methods.
Published Starving cells hijack protein transport stations
(via sciencedaily.com) Original source Study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions.
Published Microbial food as a strategy food production of the future
(via sciencedaily.com) Original source Scientists have summarized microbial food production strategies.
Published Innovative antiviral defense with new CRISPR tool
(via sciencedaily.com) Original source The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA viruses replicate. Scientists have devised a solution: Cas13d-NCS. This new molecular tool allows CRISPR RNA molecules that are located within the nucleus of a cell to move to the cytoplasm, making it highly effective at neutralizing RNA viruses. This advancement opens doors for precision medicine and proactive viral defense strategies.
Published First step to untangle DNA: Supercoiled DNA captures gyrase like a lasso ropes cattle
(via sciencedaily.com) Original source Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications. Gyrases are biomedical targets for the treatment of bacterial infections and the similar human versions of the enzymes are targets for many anti-cancer drugs. Better understanding of how gyrases work at the molecular level can potentially improve clinical treatments.
Published New approach for combating 'resting' bacteria
(via sciencedaily.com) Original source Most disease-causing bacteria are known for their speed: In mere minutes, they can double their population, quickly making a person sick. But just as dangerous as this rapid growth can be a bacterium's resting state, which helps the pathogen evade antibiotics and contributes to severe chronic infections in the lungs and blood, within wounds, and on the surfaces of medical devices. Now, scientists have discovered how long chains of molecules called polyphosphates (polyP) are needed for bacteria to slow down movements within cells and let them enter this resting state.
Published Rock permeability, microquakes link may be a boon for geothermal energy
(via sciencedaily.com) Original source Using machine learning, researchers have tied low-magnitude microearthquakes to the permeability of subsurface rocks beneath the Earth, a discovery that could have implications for improving geothermal energy transfer.
Published Biofortified rice to combat deficiencies
(via sciencedaily.com) Original source Vitamin B1 is an essential micronutrient for human beings. Its deficiency is the cause of numerous diseases of the nervous and cardiovascular systems. Researchers have achieved a significant advance in the fight against vitamin B1 deficiency, frequently associated with a rice-based diet. By specifically targeting the nourishing tissues of the rice grain, the scientists have succeeded in considerably increasing its vitamin B1 content, without compromising agronomic yield. These results could help solve a major public health problem in regions where rice is the staple food.
Published Genetic underpinnings of environmental stress identified in model plant
(via sciencedaily.com) Original source Researchers have identified 14 genes that thale cress -- a plant commonly used in genetic investigations since its genome is well documented -- express more when responding to five specific stressors, as well as eight genes that the plant suppresses.
Published Geobiology: New placozoan habitat discovered
(via sciencedaily.com) Original source Traces of DNA in the stomachs of predatory snails give a team og geobiologists new insights into the ecology of placozoans.
Published New drug prevents flu-related inflammation and lung damage
(via sciencedaily.com) Original source Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.
Published Researchers discover how we perceive bitter taste
(via sciencedaily.com) Original source A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.