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Categories: Biology: Biotechnology, Chemistry: Thermodynamics
Published Researchers develop comprehensive genetic map for bison, discover gene responsible for albinism



Researchers have determined the gene mutation responsible for an observable trait in bison -- albinism.
Published Scientists have solved the damselfly color mystery



For over 20 years, a research team has studied the common bluetail damselfly. Females occur in three different color forms -- one with a male-like appearance, something that protects them from mating harassment. In a new study, an international research team found that this genetic color variation that is shared between several species arose through changes in a specific genomic region at least five million years ago.
Published Heart repair via neuroimmune crosstalk



Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers now report.
Published New method to help with analysis of single cell data



CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout. The ability to study cells concurrently offers unprecedented insights into new cell types, disease states or other conditions. While CITE-seq solves the problem of detecting a limited number of proteins while using single-cell sequencing in an unbiased way, one of its limitations is the high levels of background noise that can hinder analysis.
Published Rediscovery of rare marine amoeba Rhabdamoeba marina



Researchers have rediscovered and successfully cultivating Rhabdamoeba marina -- a rare marine amoeba that has only been reported in two cases in the past century. Using this culture strain, they performed a comprehensive analysis of its genetic sequence, revealing for the first time the phylogenetic position of this enigmatic amoeba, and proposed a novel taxonomic classification based on their research findings.
Published Genomic tug of war could boost cancer therapy



Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.
Published How cell identity is preserved when cells divide



A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation. Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.
Published Much more than waste: Tiny vesicles exchange genetic information between cells in the sea



Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.
Published More than meows: How bacteria help cats communicate



Many mammals, from domestic cats and dogs to giant pandas, use scent to communicate with each other. A new study shows how domestic cats send signals to each other using odors derived from families of bacteria living in their anal glands.
Published No one-size-fits-all solution for the net-zero grid



As power generation from sources like solar and wind increases, along with the introduction of devices such as heat pumps and batteries, a new optimization tool will help the UK plan for a greener electricity network. The researchers developed an algorithm to model how these smaller networks distributed electricity -- factoring in how local grids could become unbalanced by adding too many heat pumps in a single area or generating more electricity than the grid could accept.
Published How bacteria recognize viral invasion and activate immune defenses



Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
Published Visualizing 'traffic jams' inside living cells



Researchers have unveiled a groundbreaking approach to label-free visualization of intracellular cargo trafficking in living cells, achieving high-speed and limitless observation capabilities. By developing a cargo-localization interferometric scattering (CL-iSCAT) microscope, scientists meticulously tracked the intricate movements of numerous cargos in the bustling cellular world. Surprisingly, cells employ human-like strategies to manage their transport challenges.
Published Colliding ribosomes activate RNA repair



Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.
Published Novel C. diff structures are required for infection, offer new therapeutic targets



Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles.
Published Shedding new light on sugars, the 'dark matter' of cellular biology



Chemists have developed a new tool for detecting interactions between sugars and lectins, a discovery that could help in the fight against diseases like cancer.
Published New tool models viability of closed-loop geothermal systems



Researchers have used computer models of closed-loop geothermal systems to determine if they would be economically viable sources of renewable energy. They found that the cost of drilling would need to decrease significantly to hit cost targets.
Published A tale of two proteins: Fundamental research could make growing better crops like clockwork



Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.
Published 'Cooling glass' blasts building heat into space



Researchers aiming to combat rising global temperatures have developed a new 'cooling glass' that can turn down the heat indoors without electricity by drawing on the cold depths of space. The new technology, a microporous glass coating, can lower the temperature of the material beneath it by 3.5 degrees Celsius at noon, and has the potential to reduce a mid-rise apartment building's yearly carbon emissions by 10 percent.
Published New discovery on how green algae count cell divisions illuminates key step needed for the evolution of multicellular life



An international research team has made an unexpected discovery of a biased counting mechanism used by the single-celled green alga Chlamydomonas to control cell division.
Published New work sheds light on inner working of cells



New research provides a deeper understanding of the way components within cells are interconnected. Through cellular visualization using SRS microscopy, researchers have addressed the challenge of attaining clear images of individual processes.