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Categories: Biology: Biotechnology, Energy: Alternative Fuels

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Traces of DNA in the stomachs of predatory snails give a team og geobiologists new insights into the ecology of placozoans.

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Findings show a newly created drug can prevent runaway inflammation while still allowing the immune system to handle the virus, even when given late into infection.

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A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.

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Researchers have developed a novel method of adding polyethylene glycol molecules to engineered groups of messenger RNAs called 'mRNA polyplexes', which enable the cells that receive them to produce specific proteins. This technique allows greater control of the site in the body to which the polyplexes are delivered, significantly advancing the field of therapeutic mRNA technologies, with applications in vaccine development and the treatment of cancer and other diseases.

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Oxide ion conductors used in solid-state fuel cells often fail to reach full potential when operating at temperatures below 500 degrees Celsius, but researchers have recently found a solution to this problem. They demonstrated high conductivity and stability in bismuth-containing Sill n oxyhalides with triple fluorite-like layers.

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Researchers decode repair mechanism during transcription of genetic information.

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Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.

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Scientists are using computer simulations and laboratory experiments to see if depleted oil and natural gas reservoirs can be used for storing carbon-free hydrogen fuel. Hydrogen is an important clean fuel: It can be made by splitting water using solar or wind power, it can be used to generate electricity and power heavy industry, and it could be used to power fuel-cell-based vehicles. Additionally, hydrogen could be stored for months and used when energy needs outpace the supply delivered by renewable energy sources.

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With climate change and rising urbanization, the likelihood and severity of urban flooding are increasing. But not all city blocks are created equal. Researchers investigated how urban layout and building structures contribute to pedestrian safety during flooding. Based on their simulated results, the team recommends modifying building corners and protective block layouts to reduce pedestrian risk.

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Researchers have compiled a detailed catalogue of bacteria living in cancer metastases. Having analyzed over 4000 tumors, they shed light on the diversity of these co-inhabitants and how they might interact with cancer cells and their surroundings. For example, certain bacteria were linked to a worse response to immunotherapy. This study paves the way to a better understanding of how bacteria help or hinder cancer (therapy), and how we can use this for patients' advantage.

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A new diagnostic tool developed by researchers can test for SARS-CoV-2 and Zika virus with the same or better accuracy as high-precision PCR tests in a matter of hours.

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Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.

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Scientists have successfully grown 'mini kidneys' in the lab and grafted them into live mice, revealing new insights into the metabolic defects and a potential therapy for polycystic kidney disease.

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Genetic analysis finds evidence suggesting that acoustic fat bodies in the heads of toothed whales were once the muscles and bone marrow of the jaw.

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Researchers have fabricated a new four-terminal organic solar cell with a tandem configuration with a 16.94% power conversion efficiency (PCE). The new device is composed by a highly transparent front cell that incorporates a transparent ultrathin silver (Ag) electrode of only 7nm, which ensures its efficient operation.

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A new dataset bridging molecular information about the poplar tree microbiome to ecosystem-level processes has been released. The project aims to inform research regarding how natural systems function, their vulnerability to a changing climate, and ultimately how plants might be engineered for better performance as sources of bioenergy and natural carbon storage.

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Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.

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The study underscores the crucial role of microbes in maintaining coral reef health, akin to the human gut microbiome. Hurricanes and disease outbreaks affect coral reef water microbial communities, leading to changes that may support further reef decline. Microbial analysis enables prompt assessment of disturbances' impacts on coral reefs, facilitating timely interventions to support reef ecosystems. Environmental DNA (eDNA) analysis offers a noninvasive approach to study coral microbial communities and diagnose reef health.

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Researchers have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational tools capable of predicting these protein-RNA interactions. The newfound ability to predict these interactions can help future work in understanding molecular pathways in the cell and pave the way for developing drugs targeting these RNA G-quadruplex binding proteins, that are found to be involved in disease such as cancer.

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Researchers have discovered a new bacterial killer that can target common lung infection caused by Burkholderia bacteria that has exciting potential for biotechnological applications.