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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Chemistry: Biochemistry Engineering: Nanotechnology Offbeat: General Offbeat: Plants and Animals
Published

DNA origami-based vaccines toward safe and highly-effective precision cancer immunotherapy      (via sciencedaily.com)     Original source 

Researchers have created a DNA origami platform called DoriVac, whose core component is a self-assembling square block-shaped nanostructure. DoriVac vaccines enabled tumor-bearing mice to better control the growth of tumors and to survive significantly longer than control mice.

Chemistry: General Chemistry: Thermodynamics Energy: Batteries
Published

Revolutionary method developed for mass-producing polymer solid electrolytes      (via sciencedaily.com)     Original source 

Scientists have unveiled a groundbreaking technique for mass-producing polymer solid electrolytes, crucial components in batteries.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Chemistry: Biochemistry Chemistry: Organic Chemistry Energy: Technology
Published

Breakthrough could make automated dosing systems universal      (via sciencedaily.com)     Original source 

Automated insulin dosing systems combine low-cost blood-glucose monitors with insulin pumps that use precision dosing to continuously regulate blood-sugar and hold it steady. Synthetic biologists have found a way to piggyback on the technology and make it universally applicable for the precision dosing of virtually any drug.

Biology: Biochemistry Biology: Biotechnology Biology: Developmental Biology: Evolutionary Biology: General Biology: Microbiology
Published

New study on mating behaviors offers clues into the evolution of attraction      (via sciencedaily.com)     Original source 

In examining the mating rituals of roundworms, researchers uncovered a unique approach to reproduction that maximizes genetic fitness.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Environmental: General Geoscience: Geochemistry Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

It's hearty, it's meaty, it's mold      (via sciencedaily.com)     Original source 

Scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Molecular
Published

Alzheimer's drug fermented with help from AI and bacteria moves closer to reality      (via sciencedaily.com)     Original source 

Researchers combined artificial intelligence and chemical biosensors to ferment the precursor of an Alzheimer's drug in bacteria.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

New bioengineered protein design shows promise in fighting COVID-19      (via sciencedaily.com)     Original source 

A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Even cells know the importance of recycling      (via sciencedaily.com)     Original source 

Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Chemistry: Biochemistry Chemistry: Organic Chemistry Engineering: Biometric
Published

New simpler and cost-effective forensics test helps identify touch DNA      (via sciencedaily.com)     Original source 

Research has found a less expensive and easier to use test to learn more about forensic touch DNA. This research has important implications for forensic investigations and being able to identify DNA from a primary contact -- someone who may have committed the crime -- as well as secondary DNA that was inadvertently and indirectly transferred through touch.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology
Published

Steroid drugs used for HRT can combat E. coli and MRSA      (via sciencedaily.com)     Original source 

Researchers have combined computational and microbiology laboratory approaches to identify existing drugs that can be repurposed to combat antibiotic-resistant bacterial infections. This research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

New computational strategy boosts the ability of drug designers to target proteins inside the membrane      (via sciencedaily.com)     Original source 

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Ecology: Endangered Species
Published

Simple trick could improve accuracy of plant genetics research      (via sciencedaily.com)     Original source 

Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Milk to the rescue for diabetics? Cow produces human insulin in milk      (via sciencedaily.com)     Original source 

An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry
Published

A simple and robust experimental process for protein engineering      (via sciencedaily.com)     Original source 

A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.

Chemistry: General Energy: Batteries Energy: Technology Offbeat: General
Published

Batteries for airborne electric vehicles that take off and land vertically      (via sciencedaily.com)     Original source 

Researchers are taking cleaner transportation to the skies by creating and evaluating new batteries for airborne electric vehicles that take off and land vertically. Researchers are developing new energy-dense materials, learning how these materials degrade under extreme conditions, and developing battery control systems.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

How a natural compound from sea squirts combats cancer      (via sciencedaily.com)     Original source 

Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Ecology: Animals Ecology: Extinction Ecology: Nature
Published

Gene flow in giraffes and what it means for their conservation      (via sciencedaily.com)     Original source 

Giraffes, with their bizarre body plan, have always held a special place in the minds of evolutionary biologists and non-experts alike. In a new study whole-genome sequencing data was used to investigate the evolutionary processes occurring within giraffes. In particular, the authors were interested in establishing whether different populations of giraffes really have been isolated from each other for extended periods of time, which is normally a requirement before new species can arise.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Marine Ecology: Sea Life
Published

Study illuminates the protective role of fluorescence in neon-colored sea anemones      (via sciencedaily.com)     Original source 

A team of researchers has uncovered a direct genetic link between fluorescence and color in sea anemones -- those soft and tentacled tide pool creatures often encountered by beachgoers.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Zoology Ecology: Extinction Environmental: General
Published

New study reveals transgenerational effects of pesticide linuron on frogs      (via sciencedaily.com)     Original source 

Grand-offspring of male frogs exposed to the pesticide linuron exhibited changes in their DNA that was linked to significant physiological impacts, a study reveals. The research highlights the profound transgenerational consequences of environmental pollution on amphibian populations, which are already under threat of extinction.