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Categories: Biology: Biotechnology, Energy: Technology

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     (via sciencedaily.com)     Original source 

A global team of researchers has invented recyclable 'water batteries' that won't catch fire or explode. The team use water to replace organic electrolytes -- which enable the flow of electric current between the positive and negative terminals -- meaning their batteries can't start a fire or blow up -- unlike their lithium-ion counterparts.

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Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.

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A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.

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Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.

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A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.

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Researchers have developed a multipronged strategy to identify the transporters used by different drugs. Their approach, which makes use of both tissue models and machine-learning algorithms, has already revealed that a commonly prescribed antibiotic and a blood-thinner can interfere with each other.

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Physicists have used complex computer simulations to develop a new design for significantly more efficient solar cells than previously available. A thin layer of organic material, known as tetracene, is responsible for the increase in efficiency.

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Scientists have developed a new radiotracer (called [18F]4-FDF) that can map how cells use fructose for energy.

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In Nara, Japan, the revered sika deer faces a dilemma as their escalating population damages local farmlands. A new study has revealed a complex situation: while the sanctuary's deer upholds a distinct genetic identity, the surrounding areas display a blend of genetic lineages. This exposes a pressing predicament: whether to cull the 'pest' deer around sanctuary or risk losing a sacred genetic legacy.

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Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.

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A key step to achieving climate neutrality in the European Union is to rapidly shift from fossil fuels to electric technologies powered by renewable energies, a new study shows. At the same time, hydrogen produced from electricity will also be indispensable in hard-to-electrify sectors such as aviation, shipping and chemicals. By 2050, electrification and hydrogen are the key strategies to reach climate neutrality based on renewable power.

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Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.

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Engineers have developed a new chip that uses light waves, rather than electricity, to perform the complex math essential to training AI. The chip has the potential to radically accelerate the processing speed of computers while also reducing their energy consumption.

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A new antibiotic overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis.

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Researchers have discovered a solid material that rapidly conducts lithium ions. Consisting of non-toxic earth-abundant elements, the new material has high enough Li ion conductivity to replace the liquid electrolytes in current Li ion battery technology, improving safety and energy capacity. The research team have synthesized the material in the laboratory, determined its structure and demonstrated it in a battery cell.

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Throughout human history, technologies have been used to make peoples' lives richer and more comfortable, but they have also contributed to a global crisis threatening Earth's climate, ecosystems and even our own survival. Researchers have suggested that industrial civilization's best way forward may entail embracing further technological advancements but doing so with greater awareness of their potential drawbacks.

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When the female gametes in plants become fertilized, a signal from the sperm activates cell division, leading to the formation of new plant seeds. This activation can also be deliberately triggered without fertilization, as researchers have shown. Their findings open up new avenues for the asexual propagation of crop plants.

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Researchers report that ancient viruses may be to thank for myelin -- and, by extension, our large, complex brains. The team found that a retrovirus-derived genetic element or 'retrotransposon' is essential for myelin production in mammals, amphibians, and fish. The gene sequence, which they dubbed 'RetroMyelin,' is likely a result of ancient viral infection, and comparisons of RetroMyelin in mammals, amphibians, and fish suggest that retroviral infection and genome-invasion events occurred separately in each of these groups.

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A research team has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect microstructural changes in models of aging and Alzheimer's disease brain neurons.

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Scientists unveil 145 genes vital for genome health, and possible strategies to curb progression of human genomic disorders.