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Categories: Biology: Biotechnology, Energy: Technology
Published How seahorse-like toxins kill insects



Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.
Published Engineering viruses to kill deadly pathogens



Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.
Published Decarbonizing the world's industries



Harmful emissions from the industrial sector could be reduced by up to 85% across the world, according to new research. The sector, which includes iron and steel, chemicals, cement, and food and drink, emits around a quarter of global greenhouse gas (GHG) emissions -- planet-warming gases that result in climate change and extreme weather.
Published Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells



New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.
Published Artificial muscles -- lighter, safer, more robust



Researchers have developed artificial muscles that are lighter, safer and more robust than their predecessors. The newly developed actuators have a novel type of shell structure and use a high-permittivity ferroelectric material that can store relatively large amounts of electrical energy. They therefore work with relatively low electrical voltage, are waterproof, more robust and safer to touch.
Published DNA particles that mimic viruses hold promise as vaccines



Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Published Asparagus and orchids are more similar than you think



How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.
Published 'Genomic time machine' reveals secrets of our DNA



Researchers reveal a novel method to uncover bits of our genetic blueprint that come from ancient genetic parasites, offering fresh insights into human evolution and health.
Published A non-allergenic wheat protein for growing better cultivated meat



As the world's population increases, cultivated or lab-grown meat -- animal muscle and fat cells grown in laboratory conditions -- has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to grow these cell cultures. Now, researchers report that the non-allergenic wheat protein glutenin successfully grew striated muscle layers and flat fat layers, which could be combined to produce meat-like textures.
Published Sound-powered sensors stand to save millions of batteries



Researchers are developing a new type of sensor that reacts to certain sound waves, causing it to vibrate. The sensor is a metamaterial that acquires its special properties through the structuring of the material. Passive sound-sensitive sensors could be used to monitor buildings, earthquakes or certain medical devices and save millions of batteries.
Published Researchers map genome for cats, dolphins, birds, and dozens of other animals



Researchers mapped genetic blueprints for 51 species including cats, dolphins, kangaroos, penguins, sharks, and turtles, a discovery that deepens our understanding of evolution and the links between humans and animals. The researchers developed novel algorithms and computer software that cut the sequencing time from months -- or decades in the case of the human genome -- to a matter of days.
Published Locusts' sense of smell boosted with custom-made nanoparticles



Scientists have harnessed the power of specially made nanostructures to enhance the neural response in a locust's brain to specific odors and to improve their identification of those odors.
Published How to shift gears in a molecular motor



Scientists have long strived to develop artificial molecular motors that can convert energy into directed motion. Researchers have now presented a solution to a challenging problem: how motion can be transferred in a controlled manner from one place to another through a 'molecular gear'. Molecular motors have the potential for use in, for example, energy storage applications and medicine.
Published Polymer power: Researchers enhance the safety of lithium batteries



Lithium-ion batteries face safety concerns as a result of internal separator issues which often lead to short circuits. Scientists have now developed a method to improve the stability and properties of separators with a layer of silicon dioxide and other functional molecules. Batteries employing these separators demonstrated improved performance and reduced growth of disruptive root-like structures, paving the way for high-safety batteries that can aid the adoption of electric vehicles and advanced energy storage systems.
Published How macrophages regulate regenerative healing in spiny mice



A team of researchers is delving deeper into the science behind how spiny mice can regenerate lost tissue and using what they learn to trigger regeneration in other types of mice -- advances which one day may be translated into humans. Whereas adult laboratory mice heal injuries with scar tissue, spiny mice have the unique ability to regrow lost skin and regenerate musculoskeletal tissues in their body.
Published Liquid lithium on the walls of a fusion device helps the plasma within maintain a hot edge



Emerging research suggests it may be easier to use fusion as a power source if liquid lithium is applied to the internal walls of the device housing the plasma. Past experiments studied solid lithium coatings and found they could enhance a plasma. The researchers were pleased they could yield similar results with liquid lithium, as it's better suited for use in a large-scale tokamak.
Published How does HIV get into the cell's cenetr to kickstart infection?



UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers. UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers.
Published DNA from preserved feces reveals ancient Japanese gut environment



DNA from ancient feces can offer archaeologists new clues about the life and health of Japanese people who lived thousands of years ago, according to a new study.
Published Sparrows uniquely adapted to Bay Area marshes are losing their uniqueness



How does loss of habitat affect the animals still living there? A genetic study of saltwater-adapted Savannah sparrows around the San Francisco Bay Area shows that the 90% loss of tidal marsh habitat has led to more interbreeding with freshwater-adapted Savannah sparrows, diminishing their genetic adaptation to saltwater, such as enlarged kidneys and larger beak. This could lessen their ability to live in a saltwater habitat.
Published Innovative microscopy technique reveals secrets of lipid synthesis inside cells



Researchers have made a pivotal discovery in the field of cellular microscopy. The team has successfully developed Two-Color Infrared Photothermal Microscopy (2C-IPM), a novel technology designed to investigate neutral lipids within lipid droplets of living cells. This new microscopy can be used with isotope labeling, which allows for the detailed monitoring of neutral lipid synthesis within individual lipid droplets.