Showing 20 articles starting at article 201

< Previous 20 articles        Next 20 articles >

Categories: Biology: Biotechnology, Engineering: Graphene

Return to the site home page

     (via sciencedaily.com)     Original source 

Scientists have designed a way to 'cloak' proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

     (via sciencedaily.com)     Original source 

Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.

     (via sciencedaily.com)     Original source 

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease.

     (via sciencedaily.com)     Original source 

Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.

     (via sciencedaily.com)     Original source 

Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.

     (via sciencedaily.com)     Original source 

Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.

     (via sciencedaily.com)     Original source 

Members of the vertebrate group including anglerfishes are unique in possessing a characteristic known as sexual parasitism, in which males temporarily attach or permanently fuse with females to mate. Now, researchers show that sexual parasitism arose during a time of major global warming and rapid transition for anglerfishes from the ocean floor to the deep, open sea.

     (via sciencedaily.com)     Original source 

A study has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.

     (via sciencedaily.com)     Original source 

Populations of canola plants genetically engineered to be resistant to herbicides can survive outside of farms, but may be gradually losing their engineered genes, reports a new study.

     (via sciencedaily.com)     Original source 

Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.

     (via sciencedaily.com)     Original source 

Scientists have created a new type of chemosensor (demonstrated for lactic acid sensing) which functions with electricity but without the need for reference electrodes or battery power.

     (via sciencedaily.com)     Original source 

Researchers describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another. The study shows that cases of this behavior, including cell cannibalism, are widespread across the tree of life. The findings challenge the common perception that cell-in-cell events are largely restricted to cancer cells. Rather, these events appear to be common across diverse organisms, from single-celled amoebas to complex multicellular animals.

     (via sciencedaily.com)     Original source 

Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.

     (via sciencedaily.com)     Original source 

Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.

     (via sciencedaily.com)     Original source 

Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed an improved periodontitis mouse model that simplifies the collection and analysis of multiple periodontal tissue types. Using this model, they clarified the role of an important signaling pathway in the inflammatory response of periodontal tissue, paving the way for better diagnostic and therapeutic strategies for periodontitis.

     (via sciencedaily.com)     Original source 

The release of captive bred animals carefully selected for their genes can make a significant contribution to the successful recovery of the dwindling wild population and avert the prospect of extinction. Despite revealing extremely low levels of genetic diversity in the wild leopard population in Oman, the research team discovered higher levels of genetic diversity in captive leopards across the region. This important genetic resource has the potential for a major role in successful recovery of the Arabian leopard.

     (via sciencedaily.com)     Original source 

Researchers experimentally investigate the impact of introducing high-density calcium on the superconductivity of calcium-intercalated bilayer graphene.

     (via sciencedaily.com)     Original source 

The study's findings show mergansers arrived in the New Zealand region at least seven million years ago from the Northern Hemisphere, in a separate colonisation event to that which led to the Brazilian merganser.

     (via sciencedaily.com)     Original source 

Scientists have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected. This new research explored the origin and evolution of the biochemical machinery that builds lignin, a structural component of plant cell walls with significant impacts on the clean energy industry.

     (via sciencedaily.com)     Original source 

Two-dimensional materials such as graphene promise to form the basis of incredibly small and fast technologies, but this requires a detailed understanding of their electronic properties. New research demonstrates that fast electronic processes can be probed by irradiating the materials with ions first.