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Published

New light shed on carboxysomes in key discovery that could boost photosynthesis      (via sciencedaily.com)     Original source 

A research team has discovered how carboxysomes, carbon-fixing structures found in some bacteria and algae, work. The breakthrough could help scientists redesign and repurpose the structures to enable plants to convert sunlight into more energy, paving the way for improved photosynthesis efficiency, potentially increasing the global food supply and mitigating global warming.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology
Published

New sex-determining mechanism in African butterfly discovered      (via sciencedaily.com)     Original source 

In a study of a species of African butterfly, researchers have discovered a previously undescribed molecular mechanism of how the sex of an embryo is initially specified.

Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry Engineering: Graphene
Published

2D all-organic perovskites: potential use in 2D electronics      (via sciencedaily.com)     Original source 

Perovskites are among the most researched topics in materials science. Recently, a research team has solved an age-old challenge to synthesize all-organic two-dimensional perovskites, extending the field into the exciting realm of 2D materials. This breakthrough opens up a new field of 2D all-organic perovskites, which holds promise for both fundamental science and potential applications.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

An epigenome editing toolkit to dissect the mechanisms of gene regulation      (via sciencedaily.com)     Original source 

A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation. This innovative approach will help to investigate the role of chromatin modifications in many biological processes, and to program desired gene activity responses, which may prove useful in disease settings.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Chemistry: Biochemistry Chemistry: Organic Chemistry Environmental: General
Published

Why is breaking down plant material for biofuels so slow?      (via sciencedaily.com)     Original source 

Tracking individual enzymes during the breakdown of cellulose for biofuel production has revealed how several roadblocks slow this process when using plant material that might otherwise go to waste. The research may lead to new ways to improve the breakdown process and make the non-edible parts of plants and other plant waste, such as forestry residue, a more competitive source of biofuels.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General
Published

Intermittent fasting protects against liver inflammation and liver cancer      (via sciencedaily.com)     Original source 

Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development. The fasting regime reduces the development of liver cancer in mice with pre-existing liver inflammation. The researchers identified two proteins in liver cells that are jointly responsible for the protective effect of fasting. An approved drug can partially mimic this effect.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology Biology: Molecular
Published

Fruit fly model identifies key regulators behind organ development      (via sciencedaily.com)     Original source 

A new computational model simulating fruit fly wing development has enabled researchers to identify previously hidden mechanisms behind organ generation. An research team developed a fruit fly model to reverse engineer the mechanisms that generate organ tissue.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Progression of herpesvirus infection remodels mitochondrial organization and metabolism      (via sciencedaily.com)     Original source 

Researchers have found that herpesvirus infection modifies the structure and normal function of the mitochondria in the host cell. The new information will help to understand the interaction between herpesvirus and host cells. Knowledge can be utilized in the development of viral treatments.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

How a 'conductor' makes sense of chaos in early mouse embryos      (via sciencedaily.com)     Original source 

The earliest stages of mammalian embryo development are like an orchestra performance, where everyone must play at the exact right moment and in perfect harmony. New research identifies one of the conductors making sense of the chaos.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Endangered Species
Published

Free-forming organelles help plants adapt to climate change      (via sciencedaily.com)     Original source 

Plants' ability to sense light and temperature, and their ability to adapt to climate change, hinges on free-forming structures in their cells whose function was, until now, a mystery. Researchers have now determined how these structures work on a molecular level, as well as where and how they form.

Biology: Biochemistry Biology: Biotechnology Biology: Evolutionary Biology: General Biology: Microbiology Computer Science: General
Published

Engineers develop innovative microbiome analysis software tools      (via sciencedaily.com)     Original source 

Engineers have developed two new graph-based computational tools for tracking genomic variation within microbiomes.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology
Published

Using advanced genetic techniques, scientists create mice with traits of Tourette disorder      (via sciencedaily.com)     Original source 

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Molecular
Published

Aligned peptide 'noodles' could enable lab-grown biological tissues      (via sciencedaily.com)     Original source 

Researchers have developed peptide-based hydrogels that mimic the aligned structure of muscle and nerve tissues, which could enable the development of functional lab-grown tissue.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Ecology: Endangered Species Ecology: Nature
Published

Genomes of 'star algae' shed light on origin of plants      (via sciencedaily.com)     Original source 

Land plants cover the surface of our planet and often tower over us. They form complex bodies with multiple organs that consist of a broad range of cell types. Developing this morphological complexity is underpinned by intricate networks of genes, whose coordinated action shapes plant bodies through various molecular mechanisms. All of these magnificent forms burst forth from a one-off evolutionary event: when plants conquered Earth's surface, known as plant terrestrialization.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New discovery of a mechanism that controls cell division      (via sciencedaily.com)     Original source 

Researchers have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of certain diseases.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Novel chemical tool for understanding membrane remodeling in the cell      (via sciencedaily.com)     Original source 

Researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell. The findings lead to a deeper understanding of how membrane remodeling works in human cells and future development of new drugs.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Scientists track 'doubling' in origin of cancer cells      (via sciencedaily.com)     Original source 

Working with human breast and lung cells, scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer cells.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology
Published

Deeper understanding of malaria parasite development unlocks opportunities to block disease spread      (via sciencedaily.com)     Original source 

Natural malaria infections have been genetically analysed at a higher resolution than ever before, giving insights that could help understand and block transmission.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Promising new treatment strategy for deadly flu-related brain disorders      (via sciencedaily.com)     Original source 

Researchers have found that a brain disorder associated with flu (influenza-associated encephalopathy, or IAE) can be caused by the influenza virus entering the brain from the blood via endothelial cells. In these cells, the researchers observed viral protein accumulation, suggesting that antivirals targeting viral transcription/translation may be useful treatments for some patients. Given the lack of effective treatments for IAE, this finding will likely improve patient care and reduce IAE-related deaths worldwide.

Biology: Biochemistry Biology: Biotechnology Biology: General Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry
Published

New approach in the synthesis of complex natural substances      (via sciencedaily.com)     Original source 

Many natural substances possess interesting characteristics, and can form the basis of new active compounds in medicine. Terpenes, for example, are a group of substances, some of which are already used in therapies against cancer, malaria or epilepsy. They are found as fragrances in cosmetics or as flavorings in food, and form the basis of new medications: Terpenes are natural substances that occur in plants, insects and sea sponges. They are difficult to produce synthetically. However, chemists are now introducing a new method of synthesis.