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Categories: Biology: Biotechnology, Engineering: Graphene
Published Resistant bacteria can remain in the body for years



Fighting disease-causing bacteria becomes more difficult when antibiotics stop working. People with pre-existing conditions in particular can carry resistant germs and suffer from repeated infections for years, according to a new study.
Published Gut bacteria can process dietary fiber into an anti-allergy weapon



Short-chain fatty acids (SCFAs), which are produced by gut bacteria from dietary fiber, regulate our immune system, but the mechanism of their action remains unknown. In a recent study, researchers investigated how SCFAs interact with mast cells, a type of white blood cell that plays a central role in allergic reactions. Their findings and insights could lead to innovative and effective anti-allergy medications, supplements, and diets, paving the way for healthier lives.
Published Key dynamics of 2D nanomaterials: View to larger-scale production



A team of researchers mapped out how flecks of 2D materials move in liquid -- knowledge that could help scientists assemble macroscopic-scale materials with the same useful properties as their 2D counterparts.
Published LSH genes associated with defining the shapes of stems, flowers and leaves required for N-fixing root nodules



The developmental regulators that confer the identity of N-fixing root nodules belong to a transcription factor family (LSH) more commonly associated with defining the shapes of stems, flowers and leaves.
Published Shining a new light on the tug-of-war between virus and host



The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host. Until now, there has been no method to globally map direct interactions of individual RNA regions in an unbiased fashion without the need for genetic modification of the target RNA or cell. Researchers have now developed a breakthrough tool that overcomes this limitation.
Published Discovery of a third RNA virus linage in extreme environments Jan 17, 2024



A research group has discovered a novel RNA viral genome from microbes inhabiting a high-temperature acidic hot spring. Their study shows that RNA viruses can live in high-temperature environments (70-80 degrees Celsius), where no RNA viruses have been observed before. In addition to the two known RNA virus kingdoms, a third kingdom may exist.
Published Machine learning guides carbon nanotechnology



Carbon nanostructures could become easier to design and synthesize thanks to a machine learning method that predicts how they grow on metal surfaces. The new approach will make it easier to exploit the unique chemical versatility of carbon nanotechnology.
Published Groundbreaking genome editing tools unlock new possibilities for precision medicine



A team of researchers has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.
Published How seahorse-like toxins kill insects



Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.
Published Engineering viruses to kill deadly pathogens



Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.
Published Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells



New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.
Published DNA particles that mimic viruses hold promise as vaccines



Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Published Asparagus and orchids are more similar than you think



How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.
Published 'Genomic time machine' reveals secrets of our DNA



Researchers reveal a novel method to uncover bits of our genetic blueprint that come from ancient genetic parasites, offering fresh insights into human evolution and health.
Published A non-allergenic wheat protein for growing better cultivated meat



As the world's population increases, cultivated or lab-grown meat -- animal muscle and fat cells grown in laboratory conditions -- has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to grow these cell cultures. Now, researchers report that the non-allergenic wheat protein glutenin successfully grew striated muscle layers and flat fat layers, which could be combined to produce meat-like textures.
Published Researchers map genome for cats, dolphins, birds, and dozens of other animals



Researchers mapped genetic blueprints for 51 species including cats, dolphins, kangaroos, penguins, sharks, and turtles, a discovery that deepens our understanding of evolution and the links between humans and animals. The researchers developed novel algorithms and computer software that cut the sequencing time from months -- or decades in the case of the human genome -- to a matter of days.
Published Coal-based product could replace sand in concrete



A new study found that graphene derived from metallurgical coke, a coal-based product, through flash Joule heating could serve not only as a reinforcing additive in cement but also as a replacement for sand in concrete.
Published How macrophages regulate regenerative healing in spiny mice



A team of researchers is delving deeper into the science behind how spiny mice can regenerate lost tissue and using what they learn to trigger regeneration in other types of mice -- advances which one day may be translated into humans. Whereas adult laboratory mice heal injuries with scar tissue, spiny mice have the unique ability to regrow lost skin and regenerate musculoskeletal tissues in their body.
Published How does HIV get into the cell's cenetr to kickstart infection?



UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers. UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers.
Published DNA from preserved feces reveals ancient Japanese gut environment



DNA from ancient feces can offer archaeologists new clues about the life and health of Japanese people who lived thousands of years ago, according to a new study.