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Categories: Biology: Biotechnology, Engineering: Graphene
Published Unlocking the secret strength of marine mussels
(via sciencedaily.com) Original source How do you create strong, yet quick-release connections between living and non-living tissues? This is a question that continues to puzzle bioengineers who aim to create materials that bond together for advanced biomedical applications. Looking to nature for inspiration, this research zeroed in on the marine mussel byssus, a fibrous holdfast, which these bivalve mollusks use to anchor themselves in seashore habitats.
Published Armed to the hilt: Study solves mystery behind bacteria's extensive weaponry
(via sciencedaily.com) Original source A new study tackles the mystery of why bacteria often carry diverse ranges of weapons. The findings show that different weapons are best suited to different competition scenarios. Short-range weapons help bacteria to invade established communities; long-range weapons are useful once established.
Published Clever dosage control mechanism of biallelic genes
(via sciencedaily.com) Original source Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.
Published Researchers decipher enzyme scissors of intestinal microbes
(via sciencedaily.com) Original source Fruit and vegetables contain a variety of plant natural products such as flavonoids, which give fruits their colour and are said to have health-promoting properties. Most plant natural products occur in nature as glycosides, i.e. chemical compounds with sugars. In order for humans to absorb the healthy plant natural products, the sugar must be split off in the intestine. Microorganisms in the intestinal flora help to speed up the process. So-called C-glycosides, i.e. plant natural products with a carbon-based bond to a sugar, would even be practically indigestible without the intestinal microbes (e.g. nothofagin in rooibos tea).
Published Releasing brakes on biocatalysis
(via sciencedaily.com) Original source Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors. These include formaldehyde, which occurs naturally as a metabolic product in cells and inhibits the particularly efficient [FeFe] hydrogenase.
Published Tracing the evolution of the 'little brain'
(via sciencedaily.com) Original source The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.
Published Nano-sized cell particles are promising intervention tool in treating infectious diseases
(via sciencedaily.com) Original source Extracellular vesicles were found to inhibit the viral infection of COVID-19 and potentially other infectious diseases.
Published Scientists harness flower 'super power' to pave the way for new drug treatments
(via sciencedaily.com) Original source Researchers have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells.
Published Scientists find both potential threats and promising resources in the thriving colonies of bacteria and fungi on ocean plastic trash
(via sciencedaily.com) Original source Scientists have found both potential threats and promising resources in the thriving colonies of bacteria and fungi on plastic trash washed up on shores.
Published New clues into the head-scratching mystery of itch
(via sciencedaily.com) Original source Scientists show for the first time that bacteria can cause itch by activating nerve cells in the skin. The findings can inform new therapies to treat itch that occurs in inflammatory skin conditions like eczema and dermatitis.
Published Nutrient found in beef and dairy improves immune response to cancer
(via sciencedaily.com) Original source Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study.
Published Team discovers rules for breaking into Pseudomonas
(via sciencedaily.com) Original source Researchers report that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that -- once it infects a person -- is notoriously difficult to treat.
Published Laser-powered 'tweezers' reveal universal mechanism viruses use to package up DNA
(via sciencedaily.com) Original source Researchers have used laser-powered ‘optical tweezers’ to reveal a universal motor mechanism used by viruses for packaging their DNA into infectious particles.
Published Researchers shed light on how one deadly pathogen makes its chemicals
(via sciencedaily.com) Original source Investigators have played a key role in deciphering a previously unidentified cluster of genes responsible for producing sartorypyrones, a chemical made by the fungal pathogen Aspergillus fumigatus, whose family causes Aspergillosis in humans.
Published Unearthing how a carnivorous fungus traps and digests worms
(via sciencedaily.com) Original source A new analysis sheds light on the molecular processes involved when a carnivorous species of fungus known as Arthrobotrys oligospora senses, traps and consumes a worm.
Published New approaches in the fight against drug resistance in malaria
(via sciencedaily.com) Original source Malaria is one of the most widespread and deadly infectious diseases worldwide. New compounds are continuously required due to the risk of malaria parasites becoming resistant to the medicines currently used. A team of researchers has now combined the anti-malaria drug artemisinin with coumarin, which, like artemisinin, is also found in plants, and developed an auto-fluorescent compound from both bioactive substances.
Published Researchers develop comprehensive genetic map for bison, discover gene responsible for albinism
(via sciencedaily.com) Original source Researchers have determined the gene mutation responsible for an observable trait in bison -- albinism.
Published Scientists have solved the damselfly color mystery
(via sciencedaily.com) Original source For over 20 years, a research team has studied the common bluetail damselfly. Females occur in three different color forms -- one with a male-like appearance, something that protects them from mating harassment. In a new study, an international research team found that this genetic color variation that is shared between several species arose through changes in a specific genomic region at least five million years ago.
Published Heart repair via neuroimmune crosstalk
(via sciencedaily.com) Original source Unlike humans, zebrafish can completely regenerate their hearts after injury. They owe this ability to the interaction between their nervous and immune systems, as researchers now report.
Published New method to help with analysis of single cell data
(via sciencedaily.com) Original source CITE-seq (cellular indexing of transcriptomes and epitopes) is an RNA sequencing-based method that simultaneously quantifies cell surface protein and transcriptomic data within a single cell readout. The ability to study cells concurrently offers unprecedented insights into new cell types, disease states or other conditions. While CITE-seq solves the problem of detecting a limited number of proteins while using single-cell sequencing in an unbiased way, one of its limitations is the high levels of background noise that can hinder analysis.