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Categories: Biology: Biotechnology, Engineering: Graphene
Published Predator-prey defense mechanisms unlock key to marine biofuel production



Researchers have unpicked the mechanism behind a marine feeding strategy that could provide a valuable renewable source of biofuel.
Published Newfound mechanism suggests drug combination could starve pancreatic cancer



A study found that a new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel.
Published Epigenetic regulator MOF drives mitochondrial metabolism



Researchers have unveiled a new mechanism for regulating mitochondrial function. The findings reveal the critical role played by the enzymatic activity of the lysine acetyltransferase MOF in maintaining mitochondrial integrity and function through acetylation of mitochondrial electron transport chain component COX17. Cells lacking MOF-mediated COX17 acetylation exhibit dramatic mitochondrial defects and impaired ability to produce energy. Underscoring the clinical relevance of these findings, the team also showed that cells from human patients with a developmental disorder caused by mutations in MOF also exhibited respiratory defects that could be ameliorated by interventions such as acetylation-mimetic COX17 or mitochondrially targeted MOF.
Published How male mosquitoes compensate for having only one X chromosome


Researchers have discovered the master regulator responsible for balancing the expression of X chromosome genes between males and females in the malaria mosquito. This discovery helps scientists better understand the evolution of the epigenetic mechanisms responsible for equalizing gene expression between the sexes. The findings may contribute to the development of new ways to prevent the spread of malaria.
Published Natural GM crops: Grasses take evolutionary shortcut by borrowing genes from their neighbors



Grass may transfer genes from their neighbors in the same way genetically modified crops are made, a new study has revealed.
Published Twisted science: New quantum ruler to explore exotic matter



Researchers have developed a 'quantum ruler' to measure and explore the strange properties of multilayered sheets of graphene, a form of carbon. The work may also lead to a new, miniaturized standard for electrical resistance that could calibrate electronic devices directly on the factory floor, eliminating the need to send them to an off-site standards laboratory.
Published New discovery may 'unlock' the future of infectious disease and cancer treatment



Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.
Published The end of genes: Routine test reveals unique divergence in genetic code



Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.
Published New open-source method to improve decoding of single-cell data



Researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data. By guiding data analysis in a unique way, Spectra can offer new insights into the complex interplay between cells — like the interactions between cancer cells and immune cells, which are critical to improving immunotherapy treatments.
Published Ruffed grouse population more resilient than expected, genetic study finds



Despite decades of decline, a genetic analysis of ruffed grouse reveals that Pennsylvania's state bird harbors more genetic diversity and connectivity than expected. The findings suggest that the iconic game bird could be maintained in persistent numbers if appropriate protections are implemented.
Published Proteins roll the dice to determine bee sex



To date it has been unclear exactly how the sex of a bee is determined. A research team comprising biologists and chemists has now identified a key gene and the molecular mechanism linked with it. They describe how this process is similar to a game involving two dice.
Published Avatars to help tailor glioblastoma therapies



Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.
Published Honeybees are more selective in their choices for nutrition than previously thought



An international research group examined which plants honeybees favor when collecting nectar and pollen. The choices honeybees make have an impact on their health and also on humans, as honeybees pollinate important crop plants.
Published Ancient technology turns plant-based cheese into 'something we want to eat'



To produce plant-based cheeses that feel and taste like dairy cheese, scientists have their sights set on fermentation. In a new research result, scientists demonstrate the potential of fermentation for producing climate-friendly cheeses that people want to eat.
Published Scientists develop 3D printing method that shows promise for repairing brain injuries



Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.
Published Graphene oxide reduces the toxicity of Alzheimer's proteins



A probable early driver of Alzheimer's disease is the accumulation of molecules called amyloid peptides. These cause cell death, and are commonly found in the brains of Alzheimer’s patients. Researchers have now shown that yeast cells that accumulate these misfolded amyloid peptides can recover after being treated with graphene oxide nanoflakes.
Published When cells go boom: Study reveals inflammation-causing gene carried by millions



Researchers have found that a genetic change that increases the risk of inflammation, through a process described as ‘explosive’ cell death, is carried by up to 3% of the global population.
Published DNA from discarded whale bones suggests loss of genetic diversity due to commercial whaling



Commercial whaling in the 20th century decimated populations of large whales but also appears to have had a lasting impact on the genetic diversity of today’s surviving whales, new research shows.
Published Preventing spread of parasitic DNA in our genomes



Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.
Published Water makes all the difference



Water is a major driving force in the formation of separate reaction compartments within cells.