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Categories: Biology: Biotechnology, Engineering: Graphene
Published Genetically modified bacteria break down plastics in saltwater



Researchers have genetically engineered a marine microorganism to break down plastic in salt water. Specifically, the modified organism can break down polyethylene terephthalate (PET), a plastic used in everything from water bottles to clothing that is a significant contributor to microplastic pollution in oceans.
Published Specialized gut immune cells pinpointed that can limit progression of inflammatory bowel disease



Researchers have characterized a specialized type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.
Published Researchers discover tissue-specific protection against protein aggregation



Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail. By understanding how different tissues tackle protein build up, this research could accelerate the identification of ways to protect tissues that are vulnerable to protein build up, possibly tackling both disease-associated protein aggregates and also age-dependent aggregates that accelerate the functional decline of tissues.
Published Making hydrogen from waste plastic could pay for itself


Researchers have found a way to harvest hydrogen from plastic waste using a low-emissions method that generates graphene as a by-product, which could help offset production costs.
Published Mysterious family of microbial proteins hijack crops' cellular plumbing



Some crop pathogens use a clever trick to multiply and spread infection: they hijack the plant's cellular plumbing. In a new study, researchers unveil a class of bacterial proteins that fold into a straw-like shape and insert themselves into the plant cell membrane, allowing the inside of the leaf to become waterlogged. The researchers also figured out a possible way to block the water channel proteins and prevent infection.
Published Natural compound found in plants inhibits deadly fungi



A new study finds that a natural compound found in many plants inhibits the growth of drug-resistant Candida fungi -- including its most virulent species, Candida auris, an emerging global health threat.
Published 'Dormant' HIV produces RNA and proteins during anti-retroviral therapy



HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops. These reservoirs have long been thought to be dormant, but two independent groups of researchers report that a subset of these cells spontaneously produce HIV RNA and proteins that may impact patients' HIV-specific immune responses.
Published Comprehensive insulin signalling map shows interplay between genes and diet



Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet.
Published Super antifreeze in cells: The ability to survive in ice and snow developed in animals far earlier than we thought



More than 400 million years ago, an insect-like animal called the springtail developed a small protein that prevents its cells from freezing.
Published Researcher helps boost immune system memory against influenza



Researchers are one step closer to making the T cell army stronger. In a recent study, researchers found that by manipulating one molecular signaling pathway in the T cells that participate in clearing influenza virus in the lungs, the strength and longevity of immunological memory produced can be improved.
Published Nutrients drive cellular reprogramming in the intestine



Researchers have unveiled an intriguing phenomenon of cellular reprogramming in mature adult organs, shedding light on a novel mechanism of adaptive growth. The study, which was conducted on fruit flies (Drosophila), provides further insights into dedifferentiation -- where specialized cells that have specific functions transform into less specialized, undifferentiated cells like stem cells.
Published These worms have rhythm



Researchers have developed a new imaging technique to observe active gene expression in real time. They found that four molecules work together to control the timing of each stage of the C. elegans worm's development. This timekeeping process could provide important clues about the natural rhythm of development in humans and other animals.
Published Bacteria generate electricity from wastewater


In a breakthrough for the field of bioelectronics, researchers have enhanced the ability of E. coli bacteria to generate electricity. The innovative approach only offers a sustainable solution for organic waste processing while outperforming previous state-of-the-art technologies, opening new horizons for versatile microbial electricity production.
Published Scientists unlock secrets of red blood cell transporter, potentially paving the way for new drugs



Researchers have identified the structure of a special transporter found in red blood cells and how it interacts with drugs. Details on the findings could lead to the development of more targeted medicines. The research team found that this transporter facilitates the movement of a substance called bicarbonate, which certain drugs can inhibit. They discovered how these drugs block the transporter and devised novel compounds capable of achieving the same effect.
Published Dog diversity unveiled by international DNA database



An international consortium of scientists isĀ using an unprecedentedly large database of canine DNA to take an unbiased look at how our furry friends evolved into the various breeds we know and love.
Published Researchers grow embryonic humanized kidneys inside pigs for 28 days



Researchers have successfully created chimeric embryos containing a combination of human and pig cells. When transferred into surrogate pig mothers, the developing humanized kidneys had normal structure and tubule formation after 28 days. This is the first time that scientists have been able to grow a solid humanized organ inside another species, though previous studies have used similar methods to generate human tissues such as blood or skeletal muscle in pigs.
Published Blood-brain barrier governs ant behavior by altering hormone levels



In many animals, including ants, the blood-brain barrier (BBB) ensures normal brain function by controlling the movement of various substances in and out of the brain. Now, researchers have made the unexpected discovery that the BBB in carpenter ants plays an active role in controlling behavior that's essential to the function of entire ant colonies. The key is production in the BBB of a particular hormone-degrading enzyme.
Published Engineers design more powerful RNA vaccines


By adding synergistic self-adjuvanting properties to COVID-19 RNA vaccines, researchers showed they could significantly boost the immune response generated in mice.
Published Genetic tools probe microbial dark matter



Genetic manipulation of a puzzling, miniscule bacteria that has lived in human mouths at least since the Middle Stone Age is elucidating the genes needed for its unusual lifestyle. These Patescibacteria in the human oral microbiome reside on the surface of another, larger host microbe. Found in many water and land environments, Patescibacteria in general lack the genes required to make many molecules necessary for life, such as the amino acids that make up proteins, the fatty acids that form membranes, and the nucleotides in DNA. This has led researchers to speculate that many of them rely on other bacteria to grow. In a new study, researchers present the first glimpse into the molecular mechanisms behind their relationship with their host cells. They also share details gleaned from fluorescent, time-lapse microsopic imaging of these bacteria as they bud and send out swarms of tiny progeny, only a fraction of which are able to establish a host relationship.
Published New compound unleashes the immune system on metastases



A new nanocomplex renders a tumor harmless -- and, on top of that, it trains the immune system to detect and eliminate metastases.