Showing 20 articles starting at article 861
< Previous 20 articles Next 20 articles >
Categories: Biology: Biotechnology, Engineering: Graphene
Published Drug decelerates bacterial race to antibiotic resistance
(via sciencedaily.com) Original source Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic effectiveness.
Published Researcher uses pressure to understand RNA dynamics
(via sciencedaily.com) Original source Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.
Published The molecular control center of our protein factories
(via sciencedaily.com) Original source Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.
Published The clue is in the glue -- Nature's secret for holding it together
(via sciencedaily.com) Original source An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.
Published Studying herpes encephalitis with mini-brains
(via sciencedaily.com) Original source The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists.
Published Unraveling the connections between the brain and gut
(via sciencedaily.com) Original source Engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the researchers could control neural circuits connecting the gut and the brain, in mice.
Published A roadmap for gene regulation in plants
(via sciencedaily.com) Original source For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture.
Published Now, every biologist can use machine learning
(via sciencedaily.com) Original source Scientists have built a new, comprehensive AutoML platform designed for biologists with little to no ML experience. New automated machine learning platform enables easy, all-in-one analysis, design, and interpretation of biological sequences with minimal coding. Their platform, called BioAutoMATED, can use sequences of nucleic acids, peptides, or glycans as input data, and its performance is comparable to other AutoML platforms while requiring minimal user input.
Published DNA can fold into complex shapes to execute new functions
(via sciencedaily.com) Original source DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study.
Published Researchers reveal mechanism of protection against breast and ovarian cancer
(via sciencedaily.com) Original source Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.
Published Scientists discover new embryonic cell type that self-destructs to protect the developing embryo
(via sciencedaily.com) Original source Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.
Published The speed of life: A zoo of cells to study developmental time
(via sciencedaily.com) Original source Researchers have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time.
Published Cryo conservation: A cool solution to saving species from extinction
(via sciencedaily.com) Original source In the face of the biodiversity crisis, and alarming data showing a 69% decline in global animal populations since 1970, researchers are banking on a cool solution to help save species from extinction. Much like egg-freezing is used to preserve human fertility options for a later date, the cryo-freezing of genetic samples taken from animals may play an essential role in curbing species extinctions. A new study sheds light on the immense potential of living cell banks, also known as cryobanks, to contribute to global conservation priorities.
Published A new tool to study complex genome interactions
(via sciencedaily.com) Original source Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.
Published Tethering of shattered chromosomal fragments paves way for new cancer therapies
(via sciencedaily.com) Original source Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.
Published Close up on aging reveals how different cell types in the body age at different pace
(via sciencedaily.com) Original source A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Published Terahertz-to-visible light conversion for future telecommunications
(via sciencedaily.com) Original source A study demonstrates that graphene-based materials can be used to efficiently convert high-frequency signals into visible light, and that this mechanism is ultrafast and tunable. These outcomes open the path to exciting applications in near-future information and communication technologies.
Published Scientists discover small RNA that regulates bacterial infection
(via sciencedaily.com) Original source Researchers have identified the major mechanism behind the transition between chronic and acute P. aeruginosa infections. Their research findings can inform the development of future treatments for life-threatening acute infections.
Published Shining potential of missing atoms
(via sciencedaily.com) Original source Single photons have applications in quantum computation, information networks, and sensors, and these can be emitted by defects in the atomically thin insulator hexagonal boron nitride (hBN). Missing nitrogen atoms have been suggested to be the atomic structure responsible for this activity, but it is difficult to controllably remove them. A team has now shown that single atoms can be kicked out using a scanning transmission electron microscope under ultra-high vacuum.
Published Scientists investigate the evolution of animal developmental mechanisms, show how some of Earth's earliest animals evolved
(via sciencedaily.com) Original source Lacking bones, brains, and even a complete gut, the body plans of simple animals like sea anemones appear to have little in common with humans and their vertebrate kin. Nevertheless, new research shows that appearances can be deceiving, and that a common genetic toolkit can be deployed in different ways to drive embryological development to produce very different adult body plans. It is well established that sea anemones, corals, and their jellyfish relatives shared a common ancestor with humans that plied the Earth's ancient oceans over 600 million years ago. A new study from the Gibson Lab, published in Current Biology on June 13, 2023, illuminates the genetic basis for body plan development in the starlet sea anemone, Nematostella vectensis. This new knowledge paints a vivid picture of how some of the earliest animals on earth progressed from egg to embryo to adult.