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Categories: Biology: Biotechnology, Space: Structures and Features

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Galaxies avoid an early death because they have a 'heart and lungs' which effectively regulate their 'breathing' and prevent them growing out of control, a new study suggests. If they didn't, the universe would have aged much faster than it has and all we would see today is huge 'zombie' galaxies teeming with dead and dying stars. That's according to a new study that investigates one of the great mysteries of the Universe -- why galaxies are not as large as astronomers would expect.

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A method to screen a wide variety of drug candidates without laborious purification steps could advance the fight against drug-resistant bacteria.

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The International Astronomical Union defines a planet as a celestial body that orbits the sun, is massive enough that gravity has forced it into a spherical shape, and has cleared away other objects near its orbit around the sun. Scientists now recognize the existence of thousands of planets, but the IAU definition applies only to those within our solar system. The new proposed definition specifies that the body may orbit one or more stars, brown dwarfs or stellar remnants and sets mass limits that should apply to planets everywhere.

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International joint research led by Akihisa Osakabe and Yoshimasa Takizawa of the University of Tokyo has clarified the molecular mechanisms in thale cresses (Arabidopsis thaliana) by which the DDM1 (Decreased in DNA Methylation 1) protein prevents the transcription of 'jumping genes.' DDM1 makes 'jumping genes' more accessible for transcription-suppressing chemical marks to be deposited. Because a variant of this protein exists in humans, the discovery provides insight into genetic conditions caused by such 'jumping gene' mutations.

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The qualities and behavior of dark matter, the invisible 'glue' of the universe, continue to be shrouded in mystery. Though galaxies are mostly made of dark matter, understanding how it is distributed within a galaxy offers clues to what this substance is, and how it's relevant to a galaxy's evolution.

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An international research team has assembled the genome and 3D chromosomal structures of a 52,000-year-old woolly mammoth -- the first time such a feat has been achieved for any ancient DNA sample. The fossilized chromosomes, which are around a million times longer than most ancient DNA fragments, provide insight into how the mammoth's genome was organized within its living cells and which genes were active within the skin tissue from which the DNA was extracted. This unprecedented level of structural detail was retained because the mammoth underwent freeze-drying shortly after it died, which meant that its DNA was preserved in a glass-like state.

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Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.

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The question of whether Mars ever supported life has captivated the imagination of scientists and the public for decades. Central to the discovery is gaining insight into the past climate of Earth's neighbor: was the planet warm and wet, with seas and rivers much like those found on our own planet? Or was it frigid and icy, and therefore potentially less prone to supporting life as we know it? A new study finds evidence to support the latter by identifying similarities between soils found on Mars and those of Canada's Newfoundland, a cold subarctic climate.

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Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.

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Up to 60% of near-Earth objects could be dark comets, mysterious asteroids that orbit the sun in our solar system that likely contain or previously contained ice and could have been one route for delivering water to Earth, according to a new study.

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Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.

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By teasing apart the therapeutic benefits from the adverse effects of new generation obesity medications, researchers found a population of neurons in the brain that controls food intake without causing nausea in an animal model.

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An unexpected find has enabled important progress to be made in the battle against harmful bacteria.

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Ancient DNA from bones and teeth hints at a role of the plague in Stone Age population collapse. Contrary to previous beliefs, the plague may have diminished Europe's populations long before the major plague outbreaks of the Middle Ages, new research shows.

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Most known black holes are either extremely massive, like the supermassive black holes that lie at the cores of large galaxies, or relatively lightweight, with a mass of under 100 times that of the Sun. Intermediate-mass black holes (IMBHs) are scarce, however, and are considered rare 'missing links' in black hole evolution.

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A international team of astronomers has made an exciting discovery about the temperate exoplanet LHS 1140 b: it could be a promising 'super-Earth' covered in ice or water.

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A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.

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Age data for certain classes of meteorite have made it possible to gain new findings on the origin of small water-rich astronomical bodies in the early solar system. These planetesimals continually supplied building materials for planets -- also for the Earth, whose original material contained little water. The Earth received its actual water through planetesimals, which emerged at low temperatures in the outer solar system, as shown by computational models carried out by an international research teach with participation by earth scientists.

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An exoplanet infamous for its deadly weather has been hiding another bizarre feature -- it reeks of rotten eggs, according to a new study of data from the James Webb Space Telescope.

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A study of ancient dingo DNA revealed that the distribution of modern dingoes across Australia, including those on K'gari (formerly Fraser Island), pre-dates European colonization and interventions like the dingo-proof fence.