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Categories: Biology: Biotechnology, Engineering: Robotics Research

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'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.

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Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study now provides important new insights into how complex epigenetic modification signatures regulate the genome. This study will pave the way for new treatments of diseases caused by faulty epigenetic machineries.

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A new study finds that exposure to chronic radiation from Chornobyl has not damaged the genomes of microscopic worms living there today -- which doesn't mean that the region is safe, the scientists caution, but suggests that these worms are exceptionally resilient.

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Harnessing a pervasive type of cellular messenger shows early experimental promise as a routine way of sampling and monitoring the body's response to prescription drug exposure. Experiments have successfully isolated drug-metabolizing enzymes from extracellular vesicles (EVs), which are widely secreted throughout the body for cellular communication.

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Researchers developed protocols for growing organoids that mimic a turtle liver, the first organoids developed for a turtle and only the second for any reptile. The discovery will aid deeper study of turtle genetics, including the cause of traits with potential medical applications for humans such as the ability to survive weeks without oxygen.

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Each year, approximately 2,000 people die annually of gallbladder cancer (GBC) in the U.S., with only one in five cases diagnosed at an early stage. With GBC rated as the first biliary tract cancer and the 17th most deadly cancer worldwide, pressing attention for proper management of disease must be addressed. For patients diagnosed, surgery is the most promising curative treatment. While there has been increasing adoption of minimally invasive surgical techniques in gastrointestinal malignancies, including utilization of laparoscopic and robotic surgery, there are reservations in utilizing minimally invasive surgery for gallbladder cancer. A new study has found that robotic-assisted surgery for GBC is as effective as traditional open and laparoscopic methods, with added benefits in precision and quicker post-operative recovery.

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Scientists provide fresh insights on the origins of life, presenting compelling evidence supporting the 'RNA World' hypothesis. The study unveils an RNA enzyme that can make accurate copies of other functional RNA strands, while also allowing new variants of the molecule to emerge over time. These remarkable capabilities suggest the earliest forms of evolution may have occurred on a molecular scale in RNA, and also bring scientists one step closer to re-creating autonomous RNA-based life in the laboratory.

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Plant biologists have uncovered an evolutionary mystery over 100 million years in the making. It turns out that sometime during the last 125 million years, tomatoes and Arabidopsis thaliana plants experienced an extreme genetic makeover. Just what happened remains unclear. But the mystery surrounds CLV3, a gene key to healthy plant growth and development.

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Robots and cameras of the future could be made of liquid crystals, thanks to a new discovery that significantly expands the potential of the chemicals already common in computer displays and digital watches. The findings are a simple and inexpensive way to manipulate the molecular properties of liquid crystals with light exposure.

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Scientists have developed a new robot that can 'mimic' the two-handed movements of care-workers as they dress an individual.

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Secrets of photosynthesis have been discovered at atomic level, shedding important new light on this plant super-power that greened the earth more than a billion years ago.

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In a recent study, 151 human participants were pitted against ChatGPT-4 in three tests designed to measure divergent thinking, which is considered to be an indicator of creative thought.

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Researchers identified the proteins of a CO2-fixing organelle, namely, 'pyrenoid,' in the marine algal group Chlorarachniophyta and revealed various pyrenoid-associated proteins among algal groups, suggesting the independent evolution of pyrenoids in different algal groups.

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Scientists have pioneered a new methodology of fabricating carbon-based quantum materials at the atomic scale by integrating scanning probe microscopy techniques and deep neural networks. This breakthrough highlights the potential of implementing artificial intelligence at the sub-angstrom scale for enhanced control over atomic manufacturing, benefiting both fundamental research and future applications.

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Researchers succeed at generating 3D visualizations of chloroplasts' copying machines.

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Researchers have discovered a key mechanism used by Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV8), to induce cancer. The research points to effective new treatment options for KSHV-associated cancers, including Kaposi's sarcoma, primary effusion lymphoma, and HHV8-associated multicentric Castleman disease.

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A technique originally devised to extract DNA from woolly mammoths and other ancient archaeological specimens can be used to potentially identify badly burned human remains, according to research.

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Neuroscientists say they have found a new function for the SYNGAP1 gene, a DNA sequence that controls memory and learning in mammals, including mice and humans.

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Researchers show how biohybrid robots based on jellyfish could be used to gather climate science data from deep in the Earth's oceans.

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Researchers have developed an innovative methodology for measuring the electrical conductivity of microbial communities. This methodology holds promise for the development of batteries and electrochemical sensors using microorganisms and may serve as a pivotal tool in elucidating the role of electricity within microbial ecosystems.