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Categories: Biology: Biotechnology, Physics: General
Published Liquid droplets shape how cells respond to change



New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.
Published AI can improve Alzheimer's treatment through the 'gut-brain axis'



Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.
Published Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases



In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.
Published Switching off the light to see better



Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.
Published Protein network dynamics during cell division



An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.
Published Breakthrough rice bran nanoparticles show promise as affordable and targeted anticancer agent



Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.
Published Superradiant atoms could push the boundaries of how precisely time can be measured



Superradiant atoms can help us measure time more precisely than ever. In a new study, researchers present a new method for measuring the time interval, the second, mitigating some of the limitations that today's most advanced atomic clocks encounter. The result could have broad implications in areas such as space travel, volcanic eruptions and GPS systems.
Published New beta-decay measurements in mirror nuclei pin down the weak nuclear force



Scientists have gained insights into the weak nuclear force from new, more sensitive studies of the beta decays of the 'mirror' nuclei lithium-8 and boron-8. The weak nuclear force drives the process of nuclear beta decay. The research found that the properties of the beta decays of lithium-8 and boron-8 are in perfect agreement with the predictions of the Standard Model.
Published New compound from blessed thistle promotes functional nerve regeneration



Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae. For centuries, it has been used as a medicinal herb as an extract or tea, e.g. to aid the digestive system. Researchers have now found a completely novel use for Cnicin. Animal models as well as human cells have shown that Cnicin significantly accelerates axon (nerve fibers) growth.
Published Compact quantum light processing



An international collaboration of researchers has achieved a significant breakthrough in quantum technology, with the successful demonstration of quantum interference among several single photons using a novel resource-efficient platform. The work represents a notable advancement in optical quantum computing that paves the way for more scalable quantum technologies.
Published Key protein regulates immune response to viruses in mammal cells



Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.
Published Energy scientists unravel the mystery of gold's glow



EPFL researchers have developed the first comprehensive model of the quantum-mechanical effects behind photoluminescence in thin gold films; a discovery that could drive the development of solar fuels and batteries.
Published Light show in living cells



Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.
Published Marine microbial populations: Potential sensors of the global change in the ocean



Animal and plant populations have been extensively studied, which has helped to understand ecosystem processes and evolutionary adaptations. However, this has not been the case with microbial populations due to the impossibility of isolating, culturing and analyzing the genetic content of the different species and their individuals in the laboratory. Therefore, although it is known that populations of microorganisms include a great diversity, this remains largely uncharacterized.
Published RNA's hidden potential: New study unveils its role in early life and future bioengineering



The origin of life continues to remain a matter of debate. The ribonucleic acid (RNA) world hypothesis proposes that 'ribozymes' which store genetic information and possess catalytic functions may have supported the activities of early life forms. Now, researchers explore how RNA elongation is regulated allosterically, shedding light on its impact on early life processes and offering insights into the fabrication of arbitrary RNA nanostructures with various modern applications.
Published Calorie restriction study reveals complexities in how diet impacts aging



The rate at which human cells age is influenced by multiple interconnected factors. New research examined how restricting calories influences telomere length and biological aging.
Published Atom-by-atom: Imaging structural transformations in 2D materials



Silicon-based electronics are approaching their physical limitations and new materials are needed to keep up with current technological demands. Two-dimensional (2D) materials have a rich array of properties, including superconductivity and magnetism, and are promising candidates for use in electronic systems, such as transistors. However, precisely controlling the properties of these materials is extraordinarily difficult.
Published Tracking a protein's fleeting shape changes



Researchers have developed a powerful, new technique to generate 'movies' of changing protein structures and speeds of up to 50 frames per second.
Published Two-dimensional nanomaterial sets record for expert-defying, counter-intuitive expansion



Engineers have developed a record-setting nanomaterial which when stretched in one direction, expands perpendicular to the applied force.
Published Researchers uncover human DNA repair by nuclear metamorphosis



Researchers have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.