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Categories: Biology: Biotechnology, Physics: General
Published How seahorse-like toxins kill insects



Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.
Published Engineering viruses to kill deadly pathogens



Antimicrobial resistance is an urgent and growing global crisis. Researchers are exploring phages, viruses that infect bacteria, as a possible solution. In the new study, researchers successfully modified DNA from four types of phages to kill a deadly pathogen. The process can also be used to produce more phage variants for further exploration.
Published Researchers discover new ways to excite spin waves with extreme infrared light



Researchers have developed a pioneering method to precisely manipulate ultrafast spin waves in antiferromagnetic materials using tailored light pulses.
Published Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells



New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.
Published Researchers craft new way to make high-temperature superconductors -- with a twist



An international team has developed a new method to make and manipulate a widely studied class of high-temperature superconductors. This technique should pave the way for the creation of unusual forms of superconductivity in previously unattainable materials.
Published Superfluids could share characteristic with common fluids



Every fluid -- from Earth's atmosphere to blood pumping through the human body -- has viscosity, a quantifiable characteristic describing how the fluid will deform when it encounters some other matter. If the viscosity is higher, the fluid flows calmly, a state known as laminar. If the viscosity decreases, the fluid undergoes the transition from laminar to turbulent flow. The degree of laminar or turbulent flow is referred to as the Reynolds number, which is inversely proportional to the viscosity. However, this Reynolds similitude does not apply to quantum superfluids. A researcher has theorized a way to examine the Reynolds similitude in superfluids, which could demonstrate the existence of quantum viscosity in superfluids.
Published DNA particles that mimic viruses hold promise as vaccines



Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Published Asparagus and orchids are more similar than you think



How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.
Published Small yet mighty: Showcasing precision nanocluster formation with molecular traps



Nanoclusters (NCs) of transition metals like cobalt or nickel have widespread applications in drug delivery and water purification, with smaller NCs exhibiting improved functionalities. Downsizing NCs is, however, usually challenging. Now, scientists have demonstrated functional NC formation with atomic-scale precision. They successfully grew cobalt NCs on flat copper surfaces using molecular arrays as traps. This breakthrough paves the way for advancements like single-atom catalysis and spintronics miniaturization.
Published 'Genomic time machine' reveals secrets of our DNA



Researchers reveal a novel method to uncover bits of our genetic blueprint that come from ancient genetic parasites, offering fresh insights into human evolution and health.
Published Scientists pull off quantum coup



Scientists have discovered a first-of-its-kind material, a 3D crystalline metal in which quantum correlations and the geometry of the crystal structure combine to frustrate the movement of electrons and lock them in place.
Published A non-allergenic wheat protein for growing better cultivated meat



As the world's population increases, cultivated or lab-grown meat -- animal muscle and fat cells grown in laboratory conditions -- has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to grow these cell cultures. Now, researchers report that the non-allergenic wheat protein glutenin successfully grew striated muscle layers and flat fat layers, which could be combined to produce meat-like textures.
Published Utilizing active microparticles for artificial intelligence



Artificial intelligence using neural networks performs calculations digitally with the help of microelectronic chips. Physicists have now created a type of neural network that works not with electricity but with so-called active colloidal particles.The researchers describe how these microparticles can be used as a physical system for artificial intelligence and the prediction of time series.
Published Researchers map genome for cats, dolphins, birds, and dozens of other animals



Researchers mapped genetic blueprints for 51 species including cats, dolphins, kangaroos, penguins, sharks, and turtles, a discovery that deepens our understanding of evolution and the links between humans and animals. The researchers developed novel algorithms and computer software that cut the sequencing time from months -- or decades in the case of the human genome -- to a matter of days.
Published How macrophages regulate regenerative healing in spiny mice



A team of researchers is delving deeper into the science behind how spiny mice can regenerate lost tissue and using what they learn to trigger regeneration in other types of mice -- advances which one day may be translated into humans. Whereas adult laboratory mice heal injuries with scar tissue, spiny mice have the unique ability to regrow lost skin and regenerate musculoskeletal tissues in their body.
Published New method flips the script on topological physics



The branch of mathematics known as topology has become a cornerstone of modern physics thanks to the remarkable -- and above all reliable -- properties it can impart to a material or system. Unfortunately, identifying topological systems, or even designing new ones, is generally a tedious process that requires exactly matching the physical system to a mathematical model. Researchers have demonstrated a model-free method for identifying topology, enabling the discovery of new topological materials using a purely experimental approach.
Published Liquid lithium on the walls of a fusion device helps the plasma within maintain a hot edge



Emerging research suggests it may be easier to use fusion as a power source if liquid lithium is applied to the internal walls of the device housing the plasma. Past experiments studied solid lithium coatings and found they could enhance a plasma. The researchers were pleased they could yield similar results with liquid lithium, as it's better suited for use in a large-scale tokamak.
Published How does HIV get into the cell's cenetr to kickstart infection?



UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers. UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers.
Published Shining a light on the hidden properties of quantum materials



Certain materials have desirable properties that are hidden and scientists can use light to uncover these properties. Researchers have used an advanced optical technique, based on terahertz time-domain spectroscopy, to learn more about a quantum material called Ta2NiSe5 (TNS).
Published DNA from preserved feces reveals ancient Japanese gut environment



DNA from ancient feces can offer archaeologists new clues about the life and health of Japanese people who lived thousands of years ago, according to a new study.