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Categories: Biology: Biotechnology, Computer Science: Artificial Intelligence (AI)

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A study has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.

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Populations of canola plants genetically engineered to be resistant to herbicides can survive outside of farms, but may be gradually losing their engineered genes, reports a new study.

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Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.

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Researchers describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another. The study shows that cases of this behavior, including cell cannibalism, are widespread across the tree of life. The findings challenge the common perception that cell-in-cell events are largely restricted to cancer cells. Rather, these events appear to be common across diverse organisms, from single-celled amoebas to complex multicellular animals.

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Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.

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See how an autonomous robot created a shock-absorbing shape no human ever could -- and what it means for designing safer helmets, packaging, car bumpers, and more.

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Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.

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Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed an improved periodontitis mouse model that simplifies the collection and analysis of multiple periodontal tissue types. Using this model, they clarified the role of an important signaling pathway in the inflammatory response of periodontal tissue, paving the way for better diagnostic and therapeutic strategies for periodontitis.

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The release of captive bred animals carefully selected for their genes can make a significant contribution to the successful recovery of the dwindling wild population and avert the prospect of extinction. Despite revealing extremely low levels of genetic diversity in the wild leopard population in Oman, the research team discovered higher levels of genetic diversity in captive leopards across the region. This important genetic resource has the potential for a major role in successful recovery of the Arabian leopard.

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The study's findings show mergansers arrived in the New Zealand region at least seven million years ago from the Northern Hemisphere, in a separate colonisation event to that which led to the Brazilian merganser.

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Using more robots to close labor gaps in the hospitality industry may backfire and cause more human workers to quit, according to a new study. The study, involving more than 620 lodging and food service employees, found that 'robot-phobia' -- specifically the fear that robots and technology will take human jobs -- increased workers' job insecurity and stress, leading to greater intentions to leave their jobs. The impact was more pronounced with employees who had real experience working with robotic technology. It also affected managers in addition to frontline workers.

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Scientists have discovered that a protein responsible for the synthesis of a key plant material evolved much earlier than suspected. This new research explored the origin and evolution of the biochemical machinery that builds lignin, a structural component of plant cell walls with significant impacts on the clean energy industry.

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Marine microbes control the flux of matter and energy essential for life in the oceans. Among them, the bacterial group SAR11 accounts for about a third of all the bacteria found in surface ocean waters. A study now reveals that at times nearly 20% of SAR11 cells are infected by viruses, significantly reducing total cell numbers. The viruses can also transform these once thriving bacteria into zombies, a phenomenon observed for the first time and widespread in the oceans.

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Plants have special corrective molecules at their disposal that can make retrospective modifications to copies of genes. However, it would appear that these 'Tipp-Ex proteins' do not have permission to work in all areas of the cell, only being used in chloroplasts and mitochondria. A study has now explained why this is the case. It suggests that the correction mechanism would otherwise modify copies that have nothing wrong with them, with fatal consequences for the cell.

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If fruit fly wings do not develop into the right shape, the flies will die. Researchers have learned how fly embryo cells develop as they need to, opening a window into human development and possible treatments for birth defects.

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A molecular biologist may have found a new 'rule of biology.' The rule challenges long-held notions that most living organisms prefer stability over instability because stability requires less energy and fewer resources.

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Large language model-based chatbots can't effectively recognize users' motivation when they are hesitant about making healthy behavior changes, but they can support those who are committed to take action, say researchers.

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A new sensor is giving researchers the best look yet at ATP levels inside living cells, enabling scientists to study in greater detail than ever before how fluctuations in this cellular currency affect the cell and contribute to disease.

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Sarcasm is notoriously tricky to convey through text, and the subtle changes in tone that convey sarcasm often confuse computer algorithms as well, limiting virtual assistants and content analysis tools. So researchers have now developed a multimodal algorithm for improved sarcasm detection that examines multiple aspects of audio recordings for increased accuracy. They used two complementary approaches -- sentiment analysis using text and emotion recognition using audio -- for a more complete picture.

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What features does a robotic guide dog need? Ask the blind, say researchers. A new study identifies how to develop robot guide dogs with insights from guide dog users and trainers.