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Categories: Biology: Biotechnology, Computer Science: Artificial Intelligence (AI)
Published Clever dosage control mechanism of biallelic genes
(via sciencedaily.com) Original source Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.
Published Researchers decipher enzyme scissors of intestinal microbes
(via sciencedaily.com) Original source Fruit and vegetables contain a variety of plant natural products such as flavonoids, which give fruits their colour and are said to have health-promoting properties. Most plant natural products occur in nature as glycosides, i.e. chemical compounds with sugars. In order for humans to absorb the healthy plant natural products, the sugar must be split off in the intestine. Microorganisms in the intestinal flora help to speed up the process. So-called C-glycosides, i.e. plant natural products with a carbon-based bond to a sugar, would even be practically indigestible without the intestinal microbes (e.g. nothofagin in rooibos tea).
Published Releasing brakes on biocatalysis
(via sciencedaily.com) Original source Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors. These include formaldehyde, which occurs naturally as a metabolic product in cells and inhibits the particularly efficient [FeFe] hydrogenase.
Published Tracing the evolution of the 'little brain'
(via sciencedaily.com) Original source The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.
Published How do you make a robot smarter? Program it to know what it doesn't know
(via sciencedaily.com) Original source Engineers have come up with a new way to teach robots to know when they don't know. The technique involves quantifying the fuzziness of human language and using that measurement to tell robots when to ask for further directions. Telling a robot to pick up a bowl from a table with only one bowl is fairly clear. But telling a robot to pick up a bowl when there are five bowls on the table generates a much higher degree of uncertainty -- and triggers the robot to ask for clarification.
Published Nano-sized cell particles are promising intervention tool in treating infectious diseases
(via sciencedaily.com) Original source Extracellular vesicles were found to inhibit the viral infection of COVID-19 and potentially other infectious diseases.
Published Scientists harness flower 'super power' to pave the way for new drug treatments
(via sciencedaily.com) Original source Researchers have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells.
Published Researchers engineer a material that can perform different tasks depending on temperature
(via sciencedaily.com) Original source Researchers report that they have developed a new composite material designed to change behaviors depending on temperature in order to perform specific tasks. These materials are poised to be part of the next generation of autonomous robotics that will interact with the environment.
Published Defending your voice against deepfakes
(via sciencedaily.com) Original source Computer scientists have developed AntiFake, a tool to protect voice recordings from unauthorized speech synthesis.
Published Scientists find both potential threats and promising resources in the thriving colonies of bacteria and fungi on ocean plastic trash
(via sciencedaily.com) Original source Scientists have found both potential threats and promising resources in the thriving colonies of bacteria and fungi on plastic trash washed up on shores.
Published New method uses crowdsourced feedback to help train robots
(via sciencedaily.com) Original source A new technique enables an AI agent to be guided by data crowdsourced asynchronously from nonexpert human users as it learns to complete a task through reinforcement learning. The method trains the robot faster and better than other approaches.
Published New clues into the head-scratching mystery of itch
(via sciencedaily.com) Original source Scientists show for the first time that bacteria can cause itch by activating nerve cells in the skin. The findings can inform new therapies to treat itch that occurs in inflammatory skin conditions like eczema and dermatitis.
Published Nutrient found in beef and dairy improves immune response to cancer
(via sciencedaily.com) Original source Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study.
Published Team discovers rules for breaking into Pseudomonas
(via sciencedaily.com) Original source Researchers report that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that -- once it infects a person -- is notoriously difficult to treat.
Published How we play together
(via sciencedaily.com) Original source Psychologists are using EEG to research what games reveal about our ability to cooperate.
Published Laser-powered 'tweezers' reveal universal mechanism viruses use to package up DNA
(via sciencedaily.com) Original source Researchers have used laser-powered ‘optical tweezers’ to reveal a universal motor mechanism used by viruses for packaging their DNA into infectious particles.
Published Researchers shed light on how one deadly pathogen makes its chemicals
(via sciencedaily.com) Original source Investigators have played a key role in deciphering a previously unidentified cluster of genes responsible for producing sartorypyrones, a chemical made by the fungal pathogen Aspergillus fumigatus, whose family causes Aspergillosis in humans.
Published Unearthing how a carnivorous fungus traps and digests worms
(via sciencedaily.com) Original source A new analysis sheds light on the molecular processes involved when a carnivorous species of fungus known as Arthrobotrys oligospora senses, traps and consumes a worm.
Published AI can 'lie and BS' like its maker, but still not intelligent like humans
(via sciencedaily.com) Original source A researcher contends that the understanding of AI is muddled by linguistics: That while indeed intelligent, AI cannot be intelligent in the way that humans are, even though 'it can lie and BS like its maker.'
Published Creativity in the age of generative AI: A new era of creative partnerships
(via sciencedaily.com) Original source Generative AI (e.g., ChatGPT) has propelled AI into the mainstream, raising concerns about job displacement and creative work. Experts now emphasize a need to focus on 'co-creativity,' the human-AI interaction instead. Extensive research is needed for comprehending co-creativity which is crucial for the future development of AI.