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Categories: Biology: Biotechnology, Space: Astronomy

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Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists have used cryo-electron microscopy to observe how lipids and proteins at the plasma membrane interact and react to mechanical stress. This work shows that, depending on conditions, small membrane regions can stabilize various lipids to trigger specific cellular responses. These discoveries confirm the existence of well-organized lipid domains and begin to reveal the role they play in cell survival.

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New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.

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A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionize the response to future pandemics, researchers report.

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A new study shows that over half of the medicines stocked in space -- staples such as pain relievers, antibiotics, allergy medicines, and sleep aids -- would expire before astronauts could return to Earth.

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A study extends the definition of a habitable zone for planets to include their star's magnetic field.

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Researchers have found a link between some of the largest and smallest objects in the cosmos: supermassive black holes and dark matter particles. Their new calculations reveal that pairs of supermassive black holes (SMBHs) can merge into a single larger black hole because of previously overlooked behavior of dark matter particles, proposing a solution to the longstanding 'final parsec problem' in astronomy.

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Scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine's most formidable foes.

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Scientists have identified the genetic mutation that causes progressive retinal atrophy in English Shepherd Dogs, which results in incurable blindness, and developed a genetic test to help eliminate the disease from future generations of the breed.

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Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential to aid in developing novel antiviral treatments and vaccines.

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Researchers have found a new way to identify genetic targets useful for control of mosquito populations, potentially offering an alternative to insecticides. Their study focused on the genetic basis of species incompatibility. They crossed Ae. aegypti, a major global arboviral disease vector, and its sibling species, Ae. mascarensis, from the Indian Ocean. When offspring is crossed back with one parent, about 10 percent of the progeny becomes intersex and is unable to reproduce.

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A little leg may reveal something big about how closely related insect species can drastically differ in body shape, according to a new study. The team imaged live cells of fruit flies in the last stages of development over several days and found a new structure that appears to help guide a section of the leg into its final shape.

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Europa and Enceladus, icy moons of Jupiter and Saturn respectively, have evidence of oceans beneath their crusts. A NASA experiment suggests -- if these oceans support life -- signatures of that life in the form of organic molecules (like amino acids and nucleic acids) could survive just under the surface ice despite the harsh, ionizing radiation on these worlds. If robotic landers were to go to these moons to look for life signs, they would not have to dig very deep to find amino acids that have survived being altered or destroyed by radiation.

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The first rumblings of the Sun's next 11-year solar cycle have been detected in sound waves inside our home star -- even though it is only halfway through its current one. This existing cycle is now at its peak, or 'solar maximum' -- which is when the Sun's magnetic field flips and its poles swap places -- until mid-2025.

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Space storms could soon be forecasted with greater accuracy than ever before thanks to a big leap forward in our understanding of exactly when a violent solar eruption may hit Earth. Scientists say it is now possible to predict the precise speed a coronal mass ejection (CME) is travelling at and when it will smash into our planet -- even before it has fully erupted from the Sun.

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Europe's next big space mission -- a telescope that will hunt for Earth-like rocky planets outside of our solar system -- is on course to launch at the end of 2026. PLATO, or PLAnetary Transits and Oscillations of stars, is being built to find nearby potentially habitable worlds around Sun-like stars that we can examine in detail.

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A group of small, freshwater animals (bdelloid rotifers) protect themselves from infections using antibiotic recipes 'stolen' from bacteria, according to new research. This raises the potential that rotifers are producing novel antimicrobials that may be less toxic to animals, including humans, than those we develop from bacteria and fungi.

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Plants and microbes are known to secrete enzymes to transform organic phosphorus into bioavailable inorganic phosphorus. Now, researchers found that iron oxide in soil performs the same transformation. Discovery is important for food security, which requires phosphorus as a crop fertilizer.

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So far, only about ten intermediate-mass black holes have been discovered in the entire universe. The newly identified black hole causes surrounding stars in a cluster to move in an unexpectedly orderly way.

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Polyphenols are generally toxic to microorganisms. In peatlands, scientists thought microorganisms avoided this toxicity by degrading polyphenols using an oxygen-dependent enzyme, and thus that low-oxygen conditions inhibit microbes' carbon cycling. However, a new study found that Arctic peatland microorganisms used alternative enzymes, with and without oxygen, to break down polyphenols. This suggests carbon stored in these ecosystems is more at risk than previously thought.

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The human genome is filled with flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago. Scientists used to think they were harmless, but new research shows that, when reawakened, they help cancer survive and thrive.