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Categories: Biology: Biotechnology, Mathematics: Puzzles
Published Curiosity promotes biodiversity



Cichlid fishes exhibit differing degrees of curiosity. The cause for this lies in their genes, as reported by researchers. This trait influences the cichlids' ability to adapt to new habitats.
Published With hybrid brains, these mice smell like a rat



Mice lacking an olfactory system have had their sense of smell restored with neurons from rats, the first time scientists have successfully integrated the sensory apparatus of one species into another.
Published Synthetic droplets cause a stir in the primordial soup



Our bodies are made up of trillions of different cells, each fulfilling their own unique function to keep us alive. How do cells move around inside these extremely complicated systems? How do they know where to go? And how did they get so complicated to begin with? Simple yet profound questions like these are at the heart of curiosity-driven basic research, which focuses on the fundamental principles of natural phenomena.
Published Scientists replace fishmeal in aquaculture with microbial protein derived from soybean processing wastewater



Scientists have successfully replaced half of the fishmeal protein in the diets of farmed Asian seabass with a 'single cell protein' cultivated from microbes in soybean processing wastewater, paving the way for more sustainable fish farming practices.
Published Advanced cell atlas opens new doors in biomedical research



Researchers have developed a web-based platform that offers an unprecedented view of the human body at the cellular level. The aim is to create an invaluable resource for researchers worldwide to increase knowledge about human health and disease.
Published How immune cells communicate to fight viruses



Chemokines are signalling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells. However, it has not yet been possible to determine which cells react to these chemokines. Researchers have now developed a new class of genetically modified mice that enables the simultaneous identification of chemokine producers and sensors.
Published Cells may possess hidden communication system



Cells constantly navigate a dynamic environment, facing ever-changing conditions and challenges. But how do cells swiftly adapt to these environmental fluctuations? A new study is answering that question by challenging our understanding of how cells function. A team of researchers suggests that cells possess a previously unknown information processing system that allows them to make rapid decisions independent of their genes.
Published Researchers uncover 'parallel universe' in tomato genetics



Researchers have made a breakthrough for evolutionary biology of the Solanaceae family, which includes peppers, potatoes and petunias.
Published Unveiling the mysteries of cell division in embryos with timelapse photography



The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells -- the cells that have a specialized function, like skin and muscle cells -- they remain elusive in the first cells of our bodies, the embryonic cells. Embryonic mitosis is notoriously difficult to study in vertebrates, as live functional analyses and -imaging of experimental embryos are technically limited, which makes it hard to track cells during embryogenesis.
Published Researchers unveil PI3K enzyme's dual accelerator and brake mechanisms



The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to slam on the breaks to this process.
Published Scientists unveil genetics behind development of gliding



Researchers explain the genomic and developmental basis of the patagium, the thin skin membrane that allows some mammalian species to soar through the air.
Published Super Mario hackers' tricks could protect software from bugs



Video gamers who exploit glitches in games can help experts better understand buggy software, students suggest.
Published Researchers create artificial cells that act like living cells



Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.
Published AI tool creates 'synthetic' images of cells for enhanced microscopy analysis



Researchers have developed a method to use an image generation AI model to create realistic images of single cells, which are then used as 'synthetic data' to train an AI model to better carry out single-cell segmentation.
Published Liquid droplets shape how cells respond to change



New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.
Published AI can improve Alzheimer's treatment through the 'gut-brain axis'



Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.
Published Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases



In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.
Published Switching off the light to see better



Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.
Published Protein network dynamics during cell division



An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.
Published Breakthrough rice bran nanoparticles show promise as affordable and targeted anticancer agent



Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.