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Categories: Biology: Biotechnology, Mathematics: Statistics

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A new study suggests that adding common bone loss drugs to azoles can improve efficacy when treating fungal infections.

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Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.

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A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.

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Giant viruses found on the Greenland ice sheet probably regulate the growth of snow algae on the ice by infecting them. Knowing how to control these viruses could help us reduce the rate of ice-melt.

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Researchers combine AI and mobile health to predict recovery from lumbar spine surgery.

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Biological processes depend on puzzle pieces coming together and interacting. Under specific conditions, these interactions can create something new without external input. This is called self-organization, as seen in a school of fish or a flock of birds. Interestingly, the mammalian embryo develops similarly. Scientists now introduce a mathematical framework that analyzes self-organization from a single cell to a multicellular organism.

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An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.

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Trout living in rivers polluted by metal from old mines across the British Isles are genetically 'isolated' from other trout, new research shows.

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Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.

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Team utilizes advanced statistical techniques to project the future groundwater depletion risk.

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Research work on symbiosis -- a mutually beneficial relationship between living organisms -- is pushing back against the newer theory of a 'single-origin' of root nodule symbiosis (RNS) -- that all symbiosis between plant root nodules and nitrogen-fixing bacteria stems from one point--instead suggesting a 'multiple-origin' theory of sybiosis which opens a better understanding for genetically engineering crops.

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Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction.

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Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.

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New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.

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A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.

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Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.

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The benefits gained with higher lifestyle scores may be associated with the positive influence of heart disease risk factors on the aging of the body and its cells, finds a new study in the Journal of the American Heart Association

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Using ancient DNA extracted from the toe bone of a museum specimen, biologists have sequenced the genome of an extinct, flightless bird called the little bush moa, shedding light into an unknown corner of avian genetic history. The work is the first complete genetic map of the turkey-sized bird whose distant living cousins include the ostrich, emu, and kiwi.

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Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

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Scientists have designed a way to 'cloak' proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.