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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Mathematics: Modeling
Published

Cracking the code of life: new AI model learns DNA's hidden language      (via sciencedaily.com)     Original source 

With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology
Published

Allergy cells' hidden secret      (via sciencedaily.com)     Original source 

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy symptoms such as tissue swelling and inflammation. Now, researchers have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils. This surprising discovery sheds new light on how our immune system works, particularly during allergic reactions.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Molecular Biology: Zoology
Published

Reduction in folate intake linked to healthier aging in animal models      (via sciencedaily.com)     Original source 

Scientists found that decreasing folate intake can support healthier metabolisms in aging animal models, challenging the conventional belief that high folate consumption universally benefits health.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Coinfecting viruses impede each other's ability to enter cells      (via sciencedaily.com)     Original source 

The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.

Biology: Zoology Ecology: Nature Ecology: Trees Environmental: Ecosystems Environmental: General Geoscience: Environmental Issues Geoscience: Geochemistry
Published

New research sheds light on relationships between plants and insects in forest ecosystems      (via sciencedaily.com)     Original source 

Researchers have published new findings on how leaf-eating insects affect forest ecosystems worldwide. Researchers are aware of how large herbivores cycle nutrients in forests. They know much less, however, about how leaf-eating insects impact forest carbon and nutrient cycling.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology
Published

Circular RNAs: The new frontier in cancer research      (via sciencedaily.com)     Original source 

Unravelling the complexities of circular RNAs (circRNAs) in cancer biology has positioned scientists on the cusp of revolutionary breakthroughs in the diagnosis and treatment of cancer. A new study predicts remarkable potential for circular RNAs to improve cancer treatment and patient outcomes within the next 5-10 years.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

What gave the first molecules their stability?      (via sciencedaily.com)     Original source 

The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team has demonstrated a mechanism that could have enabled the first RNA molecules to stabilize in the primordial soup. When two RNA strands combine, their stability and lifespan increase significantly.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Offbeat: General Offbeat: Plants and Animals
Published

When it comes to DNA replication, humans and baker's yeast are more alike than different      (via sciencedaily.com)     Original source 

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from falling off the DNA strand.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology
Published

Which strains of tuberculosis are the most infectious?      (via sciencedaily.com)     Original source 

Highly localized TB strains are less infectious in cosmopolitan cities and more likely to infect people from the geographic area that is the strain's natural habitat. The research provides the first controlled evidence that TB strains may evolve with their human hosts, adapting to be more infectious to specific populations. The findings offer new clues for tailoring preventive treatments after exposure to TB based on affinity between strains host populations.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Talking about regeneration      (via sciencedaily.com)     Original source 

Researchers transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry
Published

The next generation of RNA chips      (via sciencedaily.com)     Original source 

An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology
Published

AI opens door to safe, effective new antibiotics to combat resistant bacteria      (via sciencedaily.com)     Original source 

In a hopeful sign for demand for more safe, effective antibiotics for humans, researchers have leveraged artificial intelligence to develop a new drug that already is showing promise in animal trials.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New principle for treating tuberculosis      (via sciencedaily.com)     Original source 

Researchers have succeeded in identifying and synthesizing a group of molecules that can act against the cause of tuberculosis in a new way. They describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Unraveling a key junction underlying muscle contraction      (via sciencedaily.com)     Original source 

Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Microbiology Ecology: Invasive Species Ecology: Nature Ecology: Trees Environmental: Ecosystems
Published

Scientists discover entirely new wood type that could be highly efficient at carbon storage      (via sciencedaily.com)     Original source 

Researchers undertaking an evolutionary survey of the microscopic structure of wood from some of the world's most iconic trees and shrubs have discovered an entirely new type of wood.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry Offbeat: General Offbeat: Plants and Animals
Published

Injury dressings in first-aid kits provide a new technique to reveal shark species after bite incidents      (via sciencedaily.com)     Original source 

Scientists have revealed that injury dressings found in first-aid kits can reliably be used to identify shark species involved in bite incidents by deploying medical gauze to gather DNA samples from aquatic equipment, such as surfboards.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Precise genetics: New CRISPR method enables efficient DNA modification      (via sciencedaily.com)     Original source 

A research group has developed a new method that further improves the existing CRISPR/Cas technologies: it allows a more precise and seamless introduction of tags into proteins at the gene level. This technology could significantly improve research on proteins in living organisms and opens up new possibilities for medical research.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Biology: Zoology
Published

What shapes a virus's pandemic potential? SARS-CoV-2 relatives yield clues      (via sciencedaily.com)     Original source 

Two of the closest known relatives to SARS-CoV-2 -- a pair of bat coronaviruses discovered by researchers in Laos -- may transmit poorly in people despite being genetically similar to the COVID-19-causing virus, a new study reveals. The findings provide clues as to why some viruses have greater 'pandemic potential' than others and how researchers might go about identifying those that do before they become widespread.