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Categories: Biology: Biotechnology, Ecology: Endangered Species
Published Designing synthetic receptors for precise cell control



Scientists have developed a groundbreaking new technique for engineering biosensors that respond sensitively to specific biomolecules, enhancing cell migration and targeting in cancer treatment. The findings could lead to more precise control over cellular processes for a wide range of therapeutic applications.
Published Under control to the very end -- how our cells kill themselves



Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers have now been able to elucidate the exact mechanism at the atomic level.
Published A guide through the genome



Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests. One of the greatest challenges in modern plant research is to identify the differences in genetic information that are responsible for this variation.
Published How plants use sugar to produce roots



Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. Botanists have demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to the research team leader.
Published Fossils of a saber-toothed top predator reveal a scramble for dominance leading up to 'the Great Dying'



A tiger-sized saber-toothed creature called Inostrancevia has previously only been found in Russia. But scientists have discovered its fossils in South Africa, suggesting that it migrated 7,000 miles across the supercontinent Pangaea during the world's worst mass extinction 252 million years ago. Heading to South Africa allowed it to fill a gap in a faraway ecosystem that had lost its top predators.
Published Synthetic biology: proteins set vesicles in motion



Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells.
Published Out of the frying pan: Coyotes, bobcats move into human-inhabited areas to avoid apex predators -- only to be killed by people



Conservationists have argued that the presence of wolves and other apex predators, so named because they have no known predators aside from people, can help keep smaller predator species in check. New research shows that in Washington state, the presence of two apex predators -- wolves and cougars -- does indeed help keep populations of two smaller predators in check. But by and large the apex predators were not killing and eating the smaller predators, known as mesopredators. Instead, they drove the two mesopredator species -- bobcats and coyotes -- into areas with higher levels of human activity. And people were finishing the job.
Published Cancer cells use a new fuel in absence of sugar



Researchers have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible therapeutic pathways. The findings show that cancer cells can adapt when they don't have access to glucose.
Published Scales or feathers? It all comes down to a few genes



Scales, spines, feathers and hair are examples of vertebrate skin appendages, which constitute a remarkably diverse group of micro-organs. Despite their natural multitude of forms, these appendages share early developmental processes at the embryonic stage. Researchers have discovered how to permanently transform the scales that normally cover the feet of chickens into feathers, by specifically modifying the expression of certain genes.
Published Assessing emotions in wild animals



A new study examines indicators of mental wellbeing in wild animals to improve conservation efforts.
Published A channel involved in pain sensation can also suppress it



Pain is good. It's the body's way to keep an animal from harming itself or repeating a dangerous mistake. But sometimes the debilitating sensation can get in the way. So evolution has devised ways to tamp that response down under certain circumstances.
Published Researchers reveal DNA repair mechanism



A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.
Published Rare tropical plant gains appetite for meat



Under certain circumstances, a rare tropical plant develops into a carnivore. A research team has now deciphered the mechanism responsible for this.
Published How superbug A. baumannii survives metal stress and resists antibiotics



The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response. The World Health Organization (WHO) recognizes it as one of the three top pathogens in critical need of new antibiotic therapies. Now, an international team, led by Macquarie University researchers Dr. Ram Maharjan and Associate Professor Amy Cain, have discovered how the superbug can survive harsh environments and then rebound, causing deadly infections. They have found a single protein that acts as a master regulator. When the protein is damaged, the bug loses its superpowers allowing it to be controlled, in a lab setting. The research is published this month in Nucleic Acids Research.
Published Phage structure captured, to benefit biotech applications



Researchers have mapped out what a commonly-used form of phage looks like, which will help design better uses in future.
Published Researcher uses mammal DNA to zoom into the human genome with unprecedented resolution



Scientists have precisely identified base pairs of the human genome that remained consistent over millions of years of mammalian evolution, and which play a crucial role in human disease. The team analyzed the genomes of 240 mammals, including humans and identified base pairs that were 'constrained' -- meaning they remained generally consistent -- across mammal species over the course of evolution. The most constrained base pairs in mammals were over seven times more likely to be causal for human disease and complex trait, and over 11 times more likely when researchers looked at the most constrained base pairs in primates alone.
Published A look inside stem cells helps create personalized regenerative medicine



Researchers have examined a specific type of stem cell with an intracellular toolkit to determine which cells are most likely to create effective cell therapies.
Published Brain-belly connection: Gut health may influence likelihood of developing Alzheimer's



A new study pinpoints 10 bacterial groups associated with Alzheimer's disease, provides new insights into the relationship between gut makeup and dementia.
Published Global warming puts whales in the Southern Ocean on a diet



In the autumn, when right whales swim towards the coasts of South Africa, they ought to be fat and stuffed full. But in recent years, they have become thinner because their food is disappearing with the melting sea ice.
Published Bacteria killing material could tackle hospital superbugs



Researchers have used a common disinfectant and antiseptic to create a new antimicrobial coating material that effectively kills bacteria and viruses, including MRSA and SARS-COV-2.