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Categories: Biology: Biotechnology, Ecology: Endangered Species
Published Ribosomes: Molecular wedge assists recycling
(via sciencedaily.com) Original source Researchers reveal how cells regenerate protein factories at endoplasmic reticulum.
Published Altering the circadian clock adapts barley to short growing seasons
(via sciencedaily.com) Original source To ensure that plants flower at the right time of year, they possess an internal clock, which enables them to measure the amount of daylight during a day. Biologists now describe that the mutation of a specific gene makes the flowering time of barley almost entirely independent of day length. This mutation can be useful for breeding varieties adapted to altered climatic conditions with relatively mild winters and hot, dry summers.
Published Compound vital for all life likely played a role in life's origin
(via sciencedaily.com) Original source A chemical compound essential to all living things has been synthesized in a lab in conditions that could have occurred on early Earth, suggesting it played a role at the outset of life.
Published Copies of antibiotic resistance genes greatly elevated in humans and livestock
(via sciencedaily.com) Original source Researchers have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. Bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance genes which are linked to 'jumping genes' that can move from strain to strain. Duplicate genes provide a mechanism for resistance to spread and enable evolving resistance to new drugs.
Published Damage to cell membranes causes cell aging
(via sciencedaily.com) Original source Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging.
Published Scientists discover link between leaky gut and accelerated biological aging
(via sciencedaily.com) Original source A professor has demonstrated a connection between viral damage to the gut and premature biological aging.
Published Increasingly similar or different? Centuries-long analysis suggests biodiversity is differentiating and homogenizing to a comparable extent
(via sciencedaily.com) Original source The tendency of communities and the species within them to become more similar or more distinct across landscapes -- biotic homogenization and differentiation -- are approximately balanced, according to a new study. This analysis is the first of its kind to provide a comprehensive assessment of how local and regional biodiversity changes combine across landscapes over centuries.
Published New evidence shows UK solar parks can provide for bees and butterflies
(via sciencedaily.com) Original source A new study shows that UK solar parks, if managed correctly, can provide vital resources to help stem the decline in the nation's bees and butterflies. The new research provides peer-reviewed field data of insect pollinators at solar parks in the UK, covering 15 sites.
Published An awkward family reunion: Sea monsters are our cousins
(via sciencedaily.com) Original source The sea lamprey, a 500-million-year-old animal with a sharp-toothed suction cup for a mouth, is the thing of nightmares. A new study discovered that the hindbrain -- the part of the brain controlling vital functions like blood pressure and heart rate -- of both sea lampreys and humans is built using an extraordinarily similar molecular and genetic toolkit.
Published Compounds in female ginseng could lead to new osteoporosis treatments
(via sciencedaily.com) Original source With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis. Although there are effective drugs for treating this metabolic bone disease, they can be expensive and have side effects, limiting their availability to some people. In the search for alternative drug candidates, researchers have discovered and fully replicated a compound from a botanical source, female ginseng, that had potent anti-osteoporotic activity in cellular tests.
Published New system triggers cellular waste disposal
(via sciencedaily.com) Original source Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.
Published Detecting pathogens faster and more accurately by melting DNA
(via sciencedaily.com) Original source A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.
Published 'The future is fungal': New research finds that fungi that live in healthy plants are sensitive to climate change
(via sciencedaily.com) Original source Findings more than a decade in the making reveal a rich diversity of beneficial fungi living in boreal forest trees, with implications for the health of forests.
Published Breakthrough in developing the PD-1-enhanced DNA vaccine for over 6-year cART-free AIDS prevention and virologic control
(via sciencedaily.com) Original source Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.
Published Researchers are using RNA in a new approach to fight HIV
(via sciencedaily.com) Original source A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
Published New model identifies drugs that shouldn't be taken together
(via sciencedaily.com) Original source Researchers have developed a multipronged strategy to identify the transporters used by different drugs. Their approach, which makes use of both tissue models and machine-learning algorithms, has already revealed that a commonly prescribed antibiotic and a blood-thinner can interfere with each other.
Published Scientists develop novel radiotracer for earlier detection of disease
(via sciencedaily.com) Original source Scientists have developed a new radiotracer (called [18F]4-FDF) that can map how cells use fructose for energy.
Published Scientists may have cracked the 'aging process' in species
(via sciencedaily.com) Original source Research shows the relationship between a species' age and its risk of going extinct could be accurately predicted by an ecological model called the 'neutral theory of biodiversity.'
Published First-ever report of nesting of incredibly rare and endangered giant turtle
(via sciencedaily.com) Original source Knowledge from local communities has resulted in the first-ever nesting evidence and discovery of a breeding population of an incredibly rare turtle in India.
Published Genetic insights and conservation challenges of Nara's sacred deer
(via sciencedaily.com) Original source In Nara, Japan, the revered sika deer faces a dilemma as their escalating population damages local farmlands. A new study has revealed a complex situation: while the sanctuary's deer upholds a distinct genetic identity, the surrounding areas display a blend of genetic lineages. This exposes a pressing predicament: whether to cull the 'pest' deer around sanctuary or risk losing a sacred genetic legacy.