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Categories: Biology: Biotechnology, Ecology: Endangered Species

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Researchers have created a new version of a microbe to compete economically with E. coli -- a bacteria commonly used as a research tool due to its ability to synthesize proteins -- to conduct low-cost and scalable synthetic biological experiments.

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A new clinical trial suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them. The findings highlight how close -- yet still far -- researchers have come to developing a cure for HIV-1.

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Sandalwood oil has been used worldwide for centuries. Now, a study is the first to demonstrate in vivo the chemo-preventive properties of a by-product of the oil in a mouse model. Results show administering alpha-santalol reduced visible prostate tumors, protected the normal tissue, and delayed progression from a precancerous condition to a high-grade form of cancer. These findings are significant because mortality in prostate cancer patients is mainly attributable to advanced stages of the disease.

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The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal stem cells and aging. The finding may make a difference when seeking ways to maintain the functional capacity of the aging gut.

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Researchers have unveiled a groundbreaking discovery shedding light on the intricate play between legume plants and nitrogen-fixing bacteria. Their study details the crucial role played by phosphorylation in driving the formation of symbiotic organs, known as nodules, on plant roots. The long-term goal is to enable symbiosis in root nodules in important crops such as barley, maize and rice to avoid the use of chemical fertilizers.

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A new 3D printing method uses ice to build a template for artificial blood vessels in engineered tissue. Researchers hope the vessels could eventually be used in artificial organ transplants or drug testing.

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Fossils of a marine animal that lived 500 million years ago, combined with computer simulations, informed the design of a new soft robot.

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Scientists have discovered five dazzling new species of eyelash vipers in the jungles and cloud forests of Colombia and Ecuador.

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Beaked whales are among the least studied mammals in the world. Now, a new study reveals surprising information about the Baird's beaked whale species.

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Researchers have made a groundbreaking discovery: a new cell that remembers allergies.

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Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers combined multiple sequencing and experimental techniques to map the relationship between known CAD variants and the biological pathways they impact.

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New research reveals that denser, and more sheltered, kelp forests can withstand serious stressors amid warming ocean temperatures.

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Researchers have identified a new approach to controlling bacterial infections. The team found a way to turn on a vital bacterial defense mechanism to fight and manage bacterial infections. The defense system, called cyclic oligonucleotide-based antiphage signaling system (CBASS), is a natural mechanism used by certain bacteria to protect themselves from viral attacks. Bacteria self-destruct as a means to prevent the spread of virus to other bacterial cells in the population.

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A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.

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Researchers have developed a new biocontainment method for limiting the escape of genetically engineered organisms used in industrial processes.

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Researchers have discovered peptide factors that function in the shoot and root systems to transport iron into the root nodules colonized by nitrogen-fixing bacteria. Moreover, these peptide factors regulate nitrogen homeostasis by maintaining a balance between nitrogen and iron concentrations in plants without rhizobial symbiosis.

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Researchers have discovered two new freshwater hyphomycete (mould) species, Acrogenospora alangii and Conioscypha yunnanensis, in southwestern China. The discovery marks the addition of these species to the Acrogenospora and Conioscypha genera, further enriching the diversity of freshwater fungi known in the region.

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Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts. Such knowledge opens the door to predictions of which enhancer variants underlie disease in order to harness the full potential of our genomes for better human health.

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A recent re-emergence and outbreak of Mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core. Now, a team of researchers lifted the mysteries of poxviral core architecture by combining various cryo-electron microscopy techniques with molecular modeling.

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A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. It will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based immunotherapies.