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Categories: Biology: Biotechnology, Ecology: Endangered Species
Published Bioinformatics: Researchers develop a new machine learning approach
(via sciencedaily.com) Original source To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published A novel pathway regulating lipid biosynthesis by fatty acids
(via sciencedaily.com) Original source Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening
(via sciencedaily.com) Original source A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging
(via sciencedaily.com) Original source Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published New rice lines for Africa offer virus protection
(via sciencedaily.com) Original source The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.
Published Spying on a shape-shifting protein
(via sciencedaily.com) Original source Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Human activity facilitates invasive plants' colonization in Mediterranean ecosystems
(via sciencedaily.com) Original source Some invasive plants can form persistent banks of seeds that remain under the soil for years, and this makes their eradication practically impossible. Over time, this invisible population of large quantities of living, buried plants -- in seed form -- will reoccupy ecosystems and displace the typical flora of the natural environment.
Published Thermal vision shows endangered numbats feel the heat of warming climate
(via sciencedaily.com) Original source Research using thermal imaging of numbats in Western Australia has found that during hot weather the endangered animals are limited to as little as ten minutes of activity in the sun before they overheat to a body temperature of greater than 40 C.
Published Protein complex discovered to control DNA repair
(via sciencedaily.com) Original source The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published A new type of plant metalloreductase maintains root growth under low phosphorus
(via sciencedaily.com) Original source Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.
Published Red deer populations in Europe: More influenced by humans than by wolves and other predators
(via sciencedaily.com) Original source A new study shows that human hunting and land use have a decisive influence on red deer density in Europe. Red deer density is only reduced when wolves, lynx and bears co-occur at the same site.
Published Iron influences plant immunity and may promote resiliency against climate change
(via sciencedaily.com) Original source Researchers discovered that plants manage iron deficiency without helping 'bad' bacteria thrive by eliminating the molecular signal for iron deficiency, and that the iron deficiency signaling pathway and the plant immune system are deeply intertwined. Their findings provide a new target for boosting plant resilience in the face of climate change, and offer new insight into plant and animal microbiomes.
Published Largest diversity study of 'magic mushrooms' investigates the evolution of psychoactive psilocybin production
(via sciencedaily.com) Original source The genomic analysis of 52 Psilocybe specimens includes 39 species that have never been sequenced. Psilocybe arose much earlier than previously thought -- about 65 million years ago -- and the authors found that psilocybin was first synthesized in mushrooms in the genus Psilocybe. Their analysis revealed two distinct gene orders within the gene cluster that produces psilocybin. The two gene patterns correspond to an ancient split in the genus, suggesting two independent acquisitions of psilocybin in its evolutionary history. The study is the first to reveal such a strong evolutionary pattern within the gene sequences underpinning the psychoactive proteins synthesis.
Published Plant warfare: The crucial function of Nrc proteins in tomato defense mechanisms
(via sciencedaily.com) Original source New research delves into the intricate defense mechanisms of tomatoes against the notorious bacterial pathogen, Pseudomonas syringae pv. tomato (Pst). It's a classic tale of nature's arms race: as pathogens evolve to outsmart plant defenses, plants counter with more sophisticated immune responses.
Published With only the pawprints, researchers study elusive bobcat
(via sciencedaily.com) Original source With DNA recovered from animal tracks, scientists revealed information about the ancestry and microbial community of bobcats without having to sample the animal directly.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne
(via sciencedaily.com) Original source An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Large-scale mapping of pig genes could pave the way for new human medicines
(via sciencedaily.com) Original source Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.
Published Nine new snail species discovered in Papua New Guinea, a biodiversity hot spot at risk
(via sciencedaily.com) Original source A new study describes nine new species of carnivorous land snails, all of which are so small they could fit together on a U.S. nickel. They present a rare opportunity to study a group that in many other places is disappearing fast. Worldwide, mollusks account for more than 50% of all recorded extinctions since the year 1500, and many of these were land snails from Pacific islands.
Published Life span increases in mice when specific brain cells are activated
(via sciencedaily.com) Original source A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.
Published Nutrition needs drive bee appetites
(via sciencedaily.com) Original source Scientists studied the foraging habits of wild bees. Their findings can help guide seed and plant choices that support and enhance wild bee populations. In short, their research showed that different bee species have different nutritional needs. Given that not all pollens are the same, bees forage accordingly to meet their unique needs. This research may help fight against pollinator declines through better design of rangeland restoration projects.