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Categories: Biology: Biotechnology, Ecology: Endangered Species
Published Study shows engineered gut bacteria can treat hypertension
(via sciencedaily.com) Original source Newly published research proves that it's possible to treat high blood pressure by using specially engineered Lactobacillus paracasei to produce a protein called ACE2 in the gut, reducing gut angiotensin II and, in turn, lowering blood pressure. The study, done in lab rats that are predisposed to hypertension and unable to naturally produce ACE2, opens new doors in the pursuit of harnessing our body's own microbiome to regulate blood pressure.
Published Discovery finds ferns produce crop-saving insecticide
(via sciencedaily.com) Original source Researchers have solved the structure of a novel insecticidal protein that is effective in protecting major crop plants like corn and soybean from pests and is naturally produced by ferns.
Published Plants transformed into detectors of dangerous chemicals
(via sciencedaily.com) Original source What if your house plant could tell you your water isn't safe? Scientists are closer to realizing this vision, having successfully engineered a plant to turn beet red in the presence of a banned, toxic pesticide.
Published Researchers develop DANGER analysis tool for the safer design of gene editing
(via sciencedaily.com) Original source A team of researchers has developed a software tool that provides a way for the safer design of genome editing in all organisms with a transcriptome. For about a decade, researchers have used the CRISPR technology for genome editing. However, there are some challenges in the use of CRISPR. The new analysis system overcomes these challenges and allows researchers to perform safer on- and off-target assessments without a reference genome. It holds the potential for applications in medicine, agriculture, and biological research.
Published Potential for injectable 'chemical vaccine' for malaria using atovaquone
(via sciencedaily.com) Original source Researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive. Malaria parasites in infected patients being treated with atovaquone tend to develop a resistance to the drug. Because of this, atovaquone by itself is not used as a malaria treatment nor has not been seen as a strong candidate for use as a preventive.
Published Soil carried on sea freight loaded with dangerous pests and diseases, research finds
(via sciencedaily.com) Original source While sea freight is recognised as a pathway for the movement of exotic organisms, there is little research that has quantified the risk. Soil collected from the external surfaces of sea freight was found to support live microorganisms, worms, seeds and insects, including various regulated biosecurity organisms. The research confirms that shipping containers provide a pathway for the movement of exotic species.
Published Can golden retrievers live longer?
(via sciencedaily.com) Original source Researchers have found a gene associated with longevity in golden retrievers, one of the most popular breeds of dogs.
Published DNA shows where Washington culvert replacements helped spawning salmon
(via sciencedaily.com) Original source University and federal scientists used genetic sleuthing to study how salmon were affected by two major culvert replacements near the city of Bellingham. One project, a major upgrade under Interstate-5, had a big impact, while the other old culvert may have been less of a barrier to fish. Authors from the UW and NOAA are studying the use of environmental DNA, or eDNA, in future environmental impact reporting.
Published You say genome editing, I say natural mutation
(via sciencedaily.com) Original source A plant geneticist and computational biologist teamed up to decipher the unpredictability of natural and engineered mutations in tomatoes. They discovered some combinations of mutations behave as expected while others are more erratic. Their work may help scientists find some order in the chaos of evolution and genome editing.
Published Waves of change: How sea-levels and climate altered the marine ecosystems at the South Pole 390-385 million years ago
(via sciencedaily.com) Original source New research reveals a chain of environmental disasters. These took place in what is today's South Africa, during an ancient time period called the Early-Middle Devonian. The crises led to the extinction of a unique group of marine animals called the Malvinoxhosan biota.
Published Physical theory improves protein folding prediction
(via sciencedaily.com) Original source Proteins are important molecules that perform a variety of functions essential to life. To function properly, many proteins must fold into specific structures. However, the way proteins fold into specific structures is still largely unknown. Researchers have developed a novel physical theory that can accurately predict how proteins fold. Their model can predict things previous models cannot. Improved knowledge of protein folding could offer huge benefits to medical research, as well as to various industrial processes.
Published Restoring the function of a human cell surface protein in yeast cells
(via sciencedaily.com) Original source Yeast cells are widely used to study G protein-coupled receptors (GPCRs), a large group of cell surface proteins in humans. However, several of these proteins lose their function when introduced into yeast cells. To tackle this issue, researchers developed an innovative strategy to restore GPCR function in yeast cells by inducing random mutations. Their findings can help understand GPCRs better and could pave the way to therapeutic breakthroughs for many diseases.
Published Stolen genes allow parasitic control of behavior
(via sciencedaily.com) Original source A research team has discovered that parasites manipulate their hosts using stolen genes that they likely acquired through a phenomenon called horizontal gene transfer.
Published New 'subway map' of Lyme disease pathways identifies potential new treatment targets
(via sciencedaily.com) Original source Scientists have developed a genome-scale metabolic model or 'subway map' of key metabolic activities of the bacterium that causes Lyme disease. Using this map, they have successfully identified two compounds that selectively target routes only used by Lyme disease to infect a host.
Published Soft optical fibers block pain while moving and stretching with the body
(via sciencedaily.com) Original source New soft, implantable fibers can deliver light to major nerves through the body. They are an experimental tool for scientists to explore the causes and potential treatments for peripheral nerve disorders in animal models.
Published Yeast speeds discovery of medicinal compounds in plants
(via sciencedaily.com) Original source Researchers have harnessed the power of baker's yeast to create a cost-effective and highly efficient approach for unraveling how plants synthesize medicinal compounds, and used the new method to identify key enzymes in a kratom tree.
Published Scientists uncover new way viruses fight back against bacteria
(via sciencedaily.com) Original source A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas biotechnologies.
Published Unlocking the secrets of cell behavior on soft substrates: A paradigm shift in mechanobiology
(via sciencedaily.com) Original source A research group has developed a new method for studying how cancer cells function in softer and stiffer tissue environments. This insight challenges the existing paradigm, opening up new possibilities for research in cancer biology and tissue engineering.
Published Whaling wiped out far more fin whales than previously thought
(via sciencedaily.com) Original source Whaling in the 20th century destroyed 99% of the Eastern North Pacific fin whale breeding population. Because there is enough genetic diversity, current conservation measures should help the population rebound without becoming inbred. The future of fin whales in the Gulf of California depends on the recovery of the Eastern North Pacific population.
Published Orchid without bumblebee on island finds wasp, loses self
(via sciencedaily.com) Original source Because the bumblebee that an orchid relies on for pollination does not exist on a remote island, the plant gets pollinated by an island wasp. Researchers found that this came at the cost of being hybridized with another orchid species adapted to being pollinated by the wasp. The finding showcases how plants in ecological relationships adapt to changing circumstances.