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Categories: Biology: Biotechnology, Ecology: Sea Life
Published New approach to Epstein-Barr virus and resulting diseases
(via sciencedaily.com) Original source The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease.
Published New 'atlas' provides unprecedented insights on how genes function in early embryo development
(via sciencedaily.com) Original source Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.
Published Designing a better nest to help endangered turtles
(via sciencedaily.com) Original source With Ontario's eight species of turtles considered at risk, a new nest designed by researchers has the potential to significantly bolster their struggling populations. The habitat is the first designed for turtles in rock barren landscapes, such as the research site around Georgian Bay. It uses moss and lichen. The researchers found that the design provided a more stable environment for incubating eggs compared to natural sites, where the probability of an egg hatching was only 10 per cent compared to 41 per cent in the created site.
Published Novel approach to interrogate tissue-specific protein-protein interactions
(via sciencedaily.com) Original source Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.
Published Constantly on the hunt for food: Harbor porpoises more vulnerable than previously thought
(via sciencedaily.com) Original source Constantly on the hunt for food: Harbor porpoises more vulnerable than previously thought to the disturbances from humans. The small whales spend more than 60 percent of their day hunting small fish to stay warm in the cold waters. New research shows that harbor porpoises spend little energy on this hunting strategy, but that it makes them vulnerable to human disturbance.
Published Tracking down the genetic causes of lupus to personalize treatment
(via sciencedaily.com) Original source Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.
Published Sexual parasitism helped anglerfish invade the deep sea during a time of global warming
(via sciencedaily.com) Original source Members of the vertebrate group including anglerfishes are unique in possessing a characteristic known as sexual parasitism, in which males temporarily attach or permanently fuse with females to mate. Now, researchers show that sexual parasitism arose during a time of major global warming and rapid transition for anglerfishes from the ocean floor to the deep, open sea.
Published Future climate impacts put whale diet at risk
(via sciencedaily.com) Original source A new study predicts future climate change impacts could disrupt the krill-heavy diet that humpback whales in the southern hemisphere consume.
Published Gene could unlock big wheat yields for a growing population
(via sciencedaily.com) Original source A study has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.
Published Escaped GMO canola plants persist long-term, but may be losing their extra genes
(via sciencedaily.com) Original source Populations of canola plants genetically engineered to be resistant to herbicides can survive outside of farms, but may be gradually losing their engineered genes, reports a new study.
Published Sweet move: a modified sugar enhances antisense oligonucleotide safety and efficacy
(via sciencedaily.com) Original source Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.
Published New insights into the degradation dynamics of organic material in the seafloor
(via sciencedaily.com) Original source Many processes in the deep sea are not yet well understood, and the role of microbial communities in particular is often a big unknown. This includes, for example, how organic material that sinks from the water surface to the ocean floor is metabolised -- an important building block for a better understanding of the global carbon cycle.
Published Study finds widespread 'cell cannibalism,' related phenomena across tree of life
(via sciencedaily.com) Original source Researchers describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another. The study shows that cases of this behavior, including cell cannibalism, are widespread across the tree of life. The findings challenge the common perception that cell-in-cell events are largely restricted to cancer cells. Rather, these events appear to be common across diverse organisms, from single-celled amoebas to complex multicellular animals.
Published Drug-like inhibitor shows promise in preventing flu
(via sciencedaily.com) Original source Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place? Now, scientists have designed drug-like molecules to do just that, by thwarting the first stage of influenza infection.
Published Studies reveal cell-by-cell changes caused when pig hearts and kidneys are transplanted into humans
(via sciencedaily.com) Original source Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.
Published Clarifying the cellular mechanisms underlying periodontitis with an improved animal model
(via sciencedaily.com) Original source Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed an improved periodontitis mouse model that simplifies the collection and analysis of multiple periodontal tissue types. Using this model, they clarified the role of an important signaling pathway in the inflammatory response of periodontal tissue, paving the way for better diagnostic and therapeutic strategies for periodontitis.
Published A rise in sea urchins and related damage to kelp forests impacts Oregon's gray whales and their food
(via sciencedaily.com) Original source A recent boom in the purple sea urchin population off the southern Oregon Coast appears to have had an indirect and negative impact on the gray whales that usually forage in the region, a new study shows.
Published Genes provide hope for the survival of Arabia's last big cat
(via sciencedaily.com) Original source The release of captive bred animals carefully selected for their genes can make a significant contribution to the successful recovery of the dwindling wild population and avert the prospect of extinction. Despite revealing extremely low levels of genetic diversity in the wild leopard population in Oman, the research team discovered higher levels of genetic diversity in captive leopards across the region. This important genetic resource has the potential for a major role in successful recovery of the Arabian leopard.
Published Evolutionary history of extinct duck revealed
(via sciencedaily.com) Original source The study's findings show mergansers arrived in the New Zealand region at least seven million years ago from the Northern Hemisphere, in a separate colonisation event to that which led to the Brazilian merganser.
Published After hundreds of years, study confirms Bermuda now home to cownose rays
(via sciencedaily.com) Original source Using citizen science, photographs, on-water observations and the combination of morphological and genetic data, researchers have provided evidence that the Atlantic cownose ray has recently made a new home in Bermuda. Results show that after hundreds of years of natural history records, this is a novel migration of Atlantic cownose rays to Bermuda.