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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Researchers uncover 'parallel universe' in tomato genetics      (via sciencedaily.com)     Original source 

Researchers have made a breakthrough for evolutionary biology of the Solanaceae family, which includes peppers, potatoes and petunias.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Molecular
Published

Unveiling the mysteries of cell division in embryos with timelapse photography      (via sciencedaily.com)     Original source 

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells -- the cells that have a specialized function, like skin and muscle cells -- they remain elusive in the first cells of our bodies, the embryonic cells. Embryonic mitosis is notoriously difficult to study in vertebrates, as live functional analyses and -imaging of experimental embryos are technically limited, which makes it hard to track cells during embryogenesis.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Researchers unveil PI3K enzyme's dual accelerator and brake mechanisms      (via sciencedaily.com)     Original source 

The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to slam on the breaks to this process.

Anthropology: General Biology: Biochemistry Biology: Evolutionary Biology: General Biology: Marine Ecology: Nature Ecology: Sea Life Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Fossils
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Bioluminescence first evolved in animals at least 540 million years ago      (via sciencedaily.com)     Original source 

Bioluminescence first evolved in animals at least 540 million years ago in a group of marine invertebrates called octocorals, according to the results of a new study. The study focuses on an ancient group of marine invertebrates that includes soft corals, pushes back the previous oldest dated example of trait by nearly 300 million years.

Biology: General Biology: Marine Biology: Zoology Ecology: Nature Ecology: Sea Life Offbeat: General Offbeat: Plants and Animals
Published

Squids' birthday influences mating      (via sciencedaily.com)     Original source 

The day a male spear squid hatches determines which mating tactic he will use throughout his life, according to new research. Spear squid (Heterololigo bleekeri) that hatch earlier in the season become 'consorts' which fight for mating opportunities. Those which hatch later become 'sneakers,' which use more clandestine mating tactics. Researchers found that the mating tactic determined by the birth date was fixed for the squid's whole life. Understanding how mating tactics are influenced by birth date, and the environmental conditions at that time, can help researchers consider how squid might be affected by climate change and the implications for marine resource management.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: General Chemistry: Organic Chemistry
Published

Researchers create artificial cells that act like living cells      (via sciencedaily.com)     Original source 

Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Mathematics: Modeling
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AI tool creates 'synthetic' images of cells for enhanced microscopy analysis      (via sciencedaily.com)     Original source 

Researchers have developed a method to use an image generation AI model to create realistic images of single cells, which are then used as 'synthetic data' to train an AI model to better carry out single-cell segmentation.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

Liquid droplets shape how cells respond to change      (via sciencedaily.com)     Original source 

New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.

Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

AI can improve Alzheimer's treatment through the 'gut-brain axis'      (via sciencedaily.com)     Original source 

Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases      (via sciencedaily.com)     Original source 

In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Microbiology Chemistry: Biochemistry Physics: Optics
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Switching off the light to see better      (via sciencedaily.com)     Original source 

Researchers used structured light and switchable fluorescent molecules to reduce the background light from the out-of-plane regions of microscope samples. This method allowed for the acquisition of images that surpassed the conventional resolution limit, and it may be useful for further study of cell clusters and other biological systems.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Protein network dynamics during cell division      (via sciencedaily.com)     Original source 

An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Molecular
Published

Breakthrough rice bran nanoparticles show promise as affordable and targeted anticancer agent      (via sciencedaily.com)     Original source 

Plant-derived nanoparticles have demonstrated significant anticancer effects. Researchers recently developed rice bran-derived nanoparticles (rbNPs) that efficiently suppressed cell proliferation and induced programmed cell death of only cancer cells. Furthermore, rbNPs successfully suppressed the growth of tumors in mice having aggressive adenocarcinoma in their peritoneal cavity, without any adverse effects. Given their low production costs and high efficacy, rbNPs hold great promise for developing affordable and safe anticancer agents.

Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Zoology
Published

New compound from blessed thistle promotes functional nerve regeneration      (via sciencedaily.com)     Original source 

Blessed thistle (Cnicus benedictus) is a plant in the family Asteraceae. For centuries, it has been used as a medicinal herb as an extract or tea, e.g. to aid the digestive system. Researchers have now found a completely novel use for Cnicin. Animal models as well as human cells have shown that Cnicin significantly accelerates axon (nerve fibers) growth.

Biology: Biochemistry Biology: General Biology: Marine Ecology: Sea Life Environmental: Ecosystems Environmental: Water Geoscience: Oceanography
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Surf clams off the coast of Virginia reappear -- and rebound      (via sciencedaily.com)     Original source 

The Atlantic surfclam, an economically valuable species that is the main ingredient in clam chowder and fried clam strips, has returned to Virginia waters in a big way, reversing a die-off that started more than two decades ago. In a comprehensive study of surfclams collected from an area about 45 miles due east from the mouth of the Chesapeake Bay, scientists found the population to be thriving and growing.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Biology: Zoology
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Key protein regulates immune response to viruses in mammal cells      (via sciencedaily.com)     Original source 

Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Light show in living cells      (via sciencedaily.com)     Original source 

Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.