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Categories: Biology: Biotechnology, Biology: Zoology
Published A new species of extinct crocodile relative rewrites life on the Triassic coastline
(via sciencedaily.com) Original source The surprising discovery of a new species of extinct crocodile relative from the Triassic Favret Formation of Nevada, USA, rewrites the story of life along the coasts during the first act of the Age of Dinosaurs. The new species Benggwigwishingasuchus eremicarminis reveals that while giant ichthyosaurs ruled the oceans, the ancient crocodile kin known as pseudosuchian archosaurs ruled the shores across the Middle Triassic globe between 247.2 and 237 million years ago.
Published Novel genome editing approach restores hearing in adult preclinical models with genetic deafness
(via sciencedaily.com) Original source Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.
Published Atlas of proteins reveals inner workings of cells
(via sciencedaily.com) Original source Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease
(via sciencedaily.com) Original source Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.
Published Discovery could help reduce adverse side effects of popular next-generation obesity medications
(via sciencedaily.com) Original source By teasing apart the therapeutic benefits from the adverse effects of new generation obesity medications, researchers found a population of neurons in the brain that controls food intake without causing nausea in an animal model.
Published Big gain in battle against harmful bacteria
(via sciencedaily.com) Original source An unexpected find has enabled important progress to be made in the battle against harmful bacteria.
Published The plague may have caused the downfall of the Stone Age farmers
(via sciencedaily.com) Original source Ancient DNA from bones and teeth hints at a role of the plague in Stone Age population collapse. Contrary to previous beliefs, the plague may have diminished Europe's populations long before the major plague outbreaks of the Middle Ages, new research shows.
Published Researchers listen to the hearts of bats in flight
(via sciencedaily.com) Original source Unique recordings show that bats can ramp up heart rate from 6 to 900 b.p.m within minutes.
Published New one-step method to make multiple edits to a cell's genome
(via sciencedaily.com) Original source A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.
Published Global database reveals large gaps in our knowledge of four-footed animals
(via sciencedaily.com) Original source Researchers developed TetrapodTraits -- a global database of animals with four feet -- which can now be applied for better ecology, evolution and conservation research.
Published Groundbreaking study reveals oceanic seabirds chase tropical cyclones
(via sciencedaily.com) Original source A new study reveals that the rare Desertas Petrels (Pterodroma deserta), a wide-ranging seabird in the North Atlantic, exhibit unique foraging behaviors during hurricane season. Contrary to other pelagic seabirds, these petrels do not avoid intense tropical cyclones but instead exploit the dynamic conditions for their benefit, providing new insights into the impact of cyclones on open ocean marine life.
Published Cracking open a tasty menu for captive marsupials to sink their teeth into
(via sciencedaily.com) Original source From sifting through topsoil for native truffles to cracking open hard shells of seeds and nuts to munch on the tasty kernels, Australia bettongs and potoroos are described as 'ecosystem engineers' in a two-way relationship between their rich diet and environmental health. However, with native ecosystems and potoroid marsupial numbers in decline, ecology and evolution experts are working to understand how difficult it is to bite into the foods these leading foragers seek out.
Published Life underground suited newly discovered dinosaur fine
(via sciencedaily.com) Original source A newly discovered ancestor of Thescelosaurus shows evidence that these animals spent at least part of their time in underground burrows. The new species contributes to a fuller understanding of life during the mid-Cretaceous -- both above and below ground.
Published Study projects major changes in North Atlantic and Arctic marine ecosystems due to climate change
(via sciencedaily.com) Original source New research predicts significant shifts in marine fish communities in the North Atlantic and Arctic Oceans as a result of climate warming.
Published Scientists discover how to improve vaccine responses to potentially deadly bacterium
(via sciencedaily.com) Original source Researchers have taken a leap forward in understanding how we might fight back against the potentially deadly MRSA bacterium. They have shown in an animal model that targeting a key suppressive immune molecule (IL-10) during the delivery of a vaccine improves the ability of the vaccine to protect against infection.
Published Ancient dingo DNA shows modern dingoes share little ancestry with modern dog breeds
(via sciencedaily.com) Original source A study of ancient dingo DNA revealed that the distribution of modern dingoes across Australia, including those on K'gari (formerly Fraser Island), pre-dates European colonization and interventions like the dingo-proof fence.
Published Restored oyster sanctuaries host more marine life
(via sciencedaily.com) Original source Oysters sanctuaries in Chesapeake Bay are working for more than just oysters. Compared to nearby harvest areas, sanctuaries contain more abundant populations of oysters and other animal life--and the presence of two common parasites isn't preventing that.
Published New bio-based tool quickly detects concerning coronavirus variants
(via sciencedaily.com) Original source Researchers have developed a bioelectric device that can detect and classify new variants of coronavirus to identify those that are most harmful. It has the potential to do the same with other viruses, as well.
Published Genomic data integration improves prediction accuracy of apple fruit traits
(via sciencedaily.com) Original source Genotyping techniques can be used to select fruit trees with desired traits at the seedling stage, increasing the efficiency of fruit tree breeding. However, so far, there are multiple different genotyping systems, each generating distinct datasets. In a recent study, Japanese scientists revealed that integrating genomic data obtained with different genotyping systems can effectively combine with historical data, leveraging the accuracy of genomic predictions.
Published Visualizing short-lived intermediate compounds produced during chemical reactions
(via sciencedaily.com) Original source Immobilizing small synthetic molecules inside protein crystals proves to be a promising avenue for studying intermediate compounds formed during chemical reactions, scientists report. By integrating this method with time-resolved serial femtosecond crystallography, they successfully visualized reaction dynamics and rapid structural changes occurring within reaction centers immobilized inside protein crystals. This innovative strategy holds significant potential for the intelligent design of drugs, catalysts, and functional materials.