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Categories: Biology: Biotechnology, Environmental: Biodiversity

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A chemical compound essential to all living things has been synthesized in a lab in conditions that could have occurred on early Earth, suggesting it played a role at the outset of life.

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The side effects of large-scale forestation initiatives could reduce the CO2 removal benefits by up to a third, a pioneering study has found.

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Researchers have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens. Bacteria exposed to higher levels of antibiotics often harbor multiple identical copies of protective antibiotic resistance genes which are linked to 'jumping genes' that can move from strain to strain. Duplicate genes provide a mechanism for resistance to spread and enable evolving resistance to new drugs.

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Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging.

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A professor has demonstrated a connection between viral damage to the gut and premature biological aging.

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The tendency of communities and the species within them to become more similar or more distinct across landscapes -- biotic homogenization and differentiation -- are approximately balanced, according to a new study. This analysis is the first of its kind to provide a comprehensive assessment of how local and regional biodiversity changes combine across landscapes over centuries.

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A new study shows that UK solar parks, if managed correctly, can provide vital resources to help stem the decline in the nation's bees and butterflies. The new research provides peer-reviewed field data of insect pollinators at solar parks in the UK, covering 15 sites.

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Every day, new areas of rainforests are converted into plantations, drastically changing tropical biodiversity and the way the ecosystem functions. Yet, the current understanding of the consequences is fragmentary: previous studies tended to examine either biodiversity or the ecosystem. An international research team brings these threads together in this study. They analyzed organisms ranging from microscopic mites and earthworms in the soil, to beetles and birds in tree canopies, comparing tropical rainforest with rubber and oil palm plantations in Sumatra, Indonesia.

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The sea lamprey, a 500-million-year-old animal with a sharp-toothed suction cup for a mouth, is the thing of nightmares. A new study discovered that the hindbrain -- the part of the brain controlling vital functions like blood pressure and heart rate -- of both sea lampreys and humans is built using an extraordinarily similar molecular and genetic toolkit.

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With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis. Although there are effective drugs for treating this metabolic bone disease, they can be expensive and have side effects, limiting their availability to some people. In the search for alternative drug candidates, researchers have discovered and fully replicated a compound from a botanical source, female ginseng, that had potent anti-osteoporotic activity in cellular tests.

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Established treatments for cancer and other diseases often focus on inhibiting harmful enzymes to mitigate their effects. However, a more innovative approach has emerged: harnessing the cell's natural waste disposal system not just to deactivate but to entirely eradicate these proteins. Researchers have previously demonstrated the efficacy of this approach through two distinct methods. Now they unveil a third system capable of targeting and disposing of previously inaccessible proteins.

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A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called digital DNA melting analysis, can produce results in under six hours, whereas culture typically requires 15 hours to several days, depending on the pathogen.

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Findings more than a decade in the making reveal a rich diversity of beneficial fungi living in boreal forest trees, with implications for the health of forests.

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Researchers found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model. The vaccinated monkeys remained free of AIDS for six years and achieved virologic control without the need for combination antiretroviral therapy (cART), a treatment used to suppress viral replication in individuals living with human immunodeficiency virus (HIV). The study also found that polyfunctional and broadly reactive effector-memory virus-specific T cells were maintained in the protected experimental macaques for over six years. The findings provide supporting evidence that the PD-1-enhanced DNA vaccine strategy holds promise as a third-generation DNA vaccine for AIDS prevention and immunotherapy.

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A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.

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Researchers have developed a multipronged strategy to identify the transporters used by different drugs. Their approach, which makes use of both tissue models and machine-learning algorithms, has already revealed that a commonly prescribed antibiotic and a blood-thinner can interfere with each other.

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A thousand kilometers south of Tokyo, far into the largest ocean on Earth, lies a chain of small, volcanic islands -- the Ogasawara Islands. Nature has been able to develop on its own terms here, far from both humans and the warm Kuroshio current, which acts like a shuttle, moving marine species from Taiwan, over the Ryukyu Islands, and up the Pacific coast of mainland Japan. With upwards of 70 % of trees and many animal species being endemic to the archipelago, the islands have been dubbed 'the Galapagos of the East', as they are valuable as both a biodiversity hotspot and a cradle of scientific discovery.

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Scientists have developed a new radiotracer (called [18F]4-FDF) that can map how cells use fructose for energy.

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Research shows the relationship between a species' age and its risk of going extinct could be accurately predicted by an ecological model called the 'neutral theory of biodiversity.'

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Knowledge from local communities has resulted in the first-ever nesting evidence and discovery of a breeding population of an incredibly rare turtle in India.