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Categories: Biology: Biotechnology, Environmental: Biodiversity
Published Nearly dead plants brought back to life: Keys to aging hidden in the leaves



Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.
Published Study throws our understanding of gene regulation for a loop



To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies



A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute



Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published Unraveling the role of supersulfides in regulating mitochondrial function and longevity



Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Published Bioinformatics: Researchers develop a new machine learning approach



To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published A novel pathway regulating lipid biosynthesis by fatty acids



Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening



A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Are bugs bugging humans or the other way around? Study reveals a few surprises



Research has determined key factors that impact biodiversity among spiders and insects in urban areas. The response of specific groups varied significantly, surprising the researchers. The study findings can help urban planners, landscapers, builders and homeowners make choices that increase biodiversity. Dozens of species previously unknown to science came to light through the study.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging



Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published New rice lines for Africa offer virus protection



The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.
Published Spying on a shape-shifting protein



Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Human activity facilitates invasive plants' colonization in Mediterranean ecosystems



Some invasive plants can form persistent banks of seeds that remain under the soil for years, and this makes their eradication practically impossible. Over time, this invisible population of large quantities of living, buried plants -- in seed form -- will reoccupy ecosystems and displace the typical flora of the natural environment.
Published Beaches and dunes globally squeezed by roads and buildings



Beaches and dunes globally squeezed by roads and buildings. Beaches and dunes are becoming increasingly trapped between rising sea levels and infrastructure. Researchers found that today, when dropped on a random beach anywhere in the world, you only need to walk 390 meters (on average) to find the nearest road or building. And while that short walking distance may seem convenient if you want a day at the beach, it's bad news for our protection against rising sea levels, drinking water supplies and biodiversity.
Published Thermal vision shows endangered numbats feel the heat of warming climate



Research using thermal imaging of numbats in Western Australia has found that during hot weather the endangered animals are limited to as little as ten minutes of activity in the sun before they overheat to a body temperature of greater than 40 C.
Published Protein complex discovered to control DNA repair



The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Ancient cities provide key datasets for urban planning, policy and predictions in the Anthropocene



A new study shows how state-of-the-art methods and perspectives from archaeology, history, and palaeoecology are shedding new light on 5,500 years of urban life.
Published Record heat in 2023 worsened global droughts, floods and wildfires



Record heat across the world profoundly impacted the global water cycle in 2023, contributing to severe storms, floods, megadroughts and bushfires, new research shows.
Published A new type of plant metalloreductase maintains root growth under low phosphorus



Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.
Published Only 18% of the global land area that is needed for human well-being and biodiversity is currently protected



An international group of researchers finds that conserving about half of global land area could maintain nearly all of nature's contributions to people and still meet biodiversity targets for tens of thousands of species. But the same priority areas are at risk of conflict with human development with only 18% of that land area protected.