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Categories: Biology: Biotechnology, Environmental: Wildfires
Published Preliminary study shows potential of Manuka honey as a nutraceutical for breast cancer
(via sciencedaily.com) Original source A new study found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment -- particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70-80% of all breast cancer cases.
Published Ancient DNA reveals Indigenous dog lineages found at Jamestown, Virginia
(via sciencedaily.com) Original source Previous scientific studies have indicated that North American dog lineages were replaced with European ones between 1492 and the present day. To better understand the timing of this replacement, researchers sequenced mitochondrial DNA from archaeological dogs. Their findings suggest a complex social history of dogs during the early colonial period.
Published Knocking out one key gene leads to autistic traits
(via sciencedaily.com) Original source Hyperactivity, repetitive behavior, and language deficits all appeared in the mice, highlighting an unexpected role the cerebellum seems to play in autism.
Published Zebrafish use surprising strategy to regrow spinal cord
(via sciencedaily.com) Original source A new study maps out a detailed atlas of all the cells involved in regenerating the zebrafish spinal cord. In an unexpected finding, the researchers showed that survival and adaptability of the severed neurons themselves is required for full spinal cord regeneration. Surprisingly, the study showed that stem cells capable of forming new neurons play a complementary role but don t lead the process.
Published Surprise finding in study of environmental bacteria could advance search for better antibiotics
(via sciencedaily.com) Original source Researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's 'envelope' or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.
Published Revealing the mysteries within microbial genomes
(via sciencedaily.com) Original source A new technique will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species within the planet's diverse microbiomes.
Published How bread dough gave rise to civilization
(via sciencedaily.com) Original source A major international study has explained how bread wheat helped to transform the ancient world on its path to becoming the iconic crop that today helps sustain a global population of eight billion.
Published Beige fat cells with a 'Sisyphus mechanism'
(via sciencedaily.com) Original source A new class of fat cells makes people healthier. The cells consume energy and produce heat through seemingly pointless biochemical reactions.
Published New mechanism of action kills cancer cells
(via sciencedaily.com) Original source Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in tumor cells. However, tumor cells have the ability to develop strategies to escape apoptosis, rendering the drugs ineffective. A research team now describes a new mechanism of action that kills cancer cells through ferroptosis.
Published A ketogenic diet could improve the response to pancreatic cancer therapy
(via sciencedaily.com) Original source Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Decoding the world's largest animal genome
(via sciencedaily.com) Original source Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.
Published Researchers call for genetically diverse models to drive innovation in drug discovery
(via sciencedaily.com) Original source Researchers unveiled an approach to drug discovery that could revolutionize how we understand and treat diseases. Their commentary explains the limitations of studies using traditional mouse models and proposes using genetically diverse mice and mouse and human cells to better predict human responses to drugs and diseases.
Published Climate change raised the odds of unprecedented wildfires in 2023-24
(via sciencedaily.com) Original source Unprecedented wildfires in Canada and parts of Amazonia last year were at least three times more likely due to climate change and contributed to high levels of CO2 emissions from burning globally, according to the a new systematic review. The State of Wildfires report takes stock of extreme wildfires of the 2023-2024 fire season (March 2023-February 2024), explains their causes, and assesses whether events could have been predicted. It also evaluates how the risk of similar events will change in future under different climate change scenarios.
Published Exciting advance in stem cell therapy
(via sciencedaily.com) Original source A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.
Published Pit-building venom mixers
(via sciencedaily.com) Original source Researchers show that the adaptation of antlions to their ecological niche has also changed their venom. They compared the venom system of antlion and closely related green lacewing larvae. Antlions produce a much more complex venom from three different venom glands than lacewing larvae do. All the venom proteins identified come from the insects themselves, not from symbiotic bacteria. Some of the toxins are new and appear to be unique to antlions. Waiting for their victims in pitfall traps in the sand, antlions can use their venom to immobilize larger prey. The venom therefore plays an important ecological role in adapting to their barren habitat.
Published Surprising insight into cancer comes from unique plant species that find different solutions to evolutionary challenges
(via sciencedaily.com) Original source A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.
Published Reduce, reuse, 're-fly-cle'
(via sciencedaily.com) Original source Black soldier flies are now commercially used to consume organic waste -- but genetic modifications proposed by bioscientists could see the insects digesting a wider variety of refuse, while also creating raw ingredients for industry.
Published Researchers ID body's 'quality control' regulator for protein folding
(via sciencedaily.com) Original source Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.
Published Low magnesium levels increase disease risk
(via sciencedaily.com) Original source A new study has identified why a diet rich in magnesium is so important for our health, reducing the risk of DNA damage and chronic degenerative disorders.
Published Taking a 'one in a million' shot to tackle dopamine-linked brain disorders
(via sciencedaily.com) Original source With the help of a tiny, transparent worm called Caenorhabditis elegans, researchers have identified novel players in dopamine signaling by taking advantage of a powerful platform generated via the Million Mutation Project (MMP) for the rapid identification of mutant genes based on their functional impact. They can seek insights from simpler organisms whose genes bear striking similarity to those found in humans and where opportunities for genetic insights to disease can be pursued more efficiently and inexpensively.