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Categories: Biology: Biotechnology, Geoscience: Earthquakes

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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology
Published

Using advanced genetic techniques, scientists create mice with traits of Tourette disorder      (via sciencedaily.com)     Original source 

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Molecular
Published

Aligned peptide 'noodles' could enable lab-grown biological tissues      (via sciencedaily.com)     Original source 

Researchers have developed peptide-based hydrogels that mimic the aligned structure of muscle and nerve tissues, which could enable the development of functional lab-grown tissue.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Ecology: Endangered Species Ecology: Nature
Published

Genomes of 'star algae' shed light on origin of plants      (via sciencedaily.com)     Original source 

Land plants cover the surface of our planet and often tower over us. They form complex bodies with multiple organs that consist of a broad range of cell types. Developing this morphological complexity is underpinned by intricate networks of genes, whose coordinated action shapes plant bodies through various molecular mechanisms. All of these magnificent forms burst forth from a one-off evolutionary event: when plants conquered Earth's surface, known as plant terrestrialization.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New discovery of a mechanism that controls cell division      (via sciencedaily.com)     Original source 

Researchers have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of certain diseases.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Novel chemical tool for understanding membrane remodeling in the cell      (via sciencedaily.com)     Original source 

Researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell. The findings lead to a deeper understanding of how membrane remodeling works in human cells and future development of new drugs.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Scientists track 'doubling' in origin of cancer cells      (via sciencedaily.com)     Original source 

Working with human breast and lung cells, scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer cells.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology
Published

Deeper understanding of malaria parasite development unlocks opportunities to block disease spread      (via sciencedaily.com)     Original source 

Natural malaria infections have been genetically analysed at a higher resolution than ever before, giving insights that could help understand and block transmission.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Promising new treatment strategy for deadly flu-related brain disorders      (via sciencedaily.com)     Original source 

Researchers have found that a brain disorder associated with flu (influenza-associated encephalopathy, or IAE) can be caused by the influenza virus entering the brain from the blood via endothelial cells. In these cells, the researchers observed viral protein accumulation, suggesting that antivirals targeting viral transcription/translation may be useful treatments for some patients. Given the lack of effective treatments for IAE, this finding will likely improve patient care and reduce IAE-related deaths worldwide.

Biology: Biochemistry Biology: Biotechnology Biology: General Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Chemistry: Organic Chemistry
Published

New approach in the synthesis of complex natural substances      (via sciencedaily.com)     Original source 

Many natural substances possess interesting characteristics, and can form the basis of new active compounds in medicine. Terpenes, for example, are a group of substances, some of which are already used in therapies against cancer, malaria or epilepsy. They are found as fragrances in cosmetics or as flavorings in food, and form the basis of new medications: Terpenes are natural substances that occur in plants, insects and sea sponges. They are difficult to produce synthetically. However, chemists are now introducing a new method of synthesis.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Activation of innate immunity: Important piece of the puzzle identified      (via sciencedaily.com)     Original source 

Researchers have deciphered the complex interplay of various enzymes around the innate immune receptor toll-like receptor 7 (TLR7), which plays an important role in defending our bodies against viruses.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics
Published

Malaria may shorten leukocyte telomeres among sub-Saharan Africans      (via sciencedaily.com)     Original source 

The length of telomeres in white blood cells, known as leukocytes, varies significantly among sub-Saharan African populations, researchers report. Moreover, leukocyte telomere length (LTL) is negatively associated with malaria endemicity and only partly explained by genetic factors.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Archaea can be picky parasites      (via sciencedaily.com)     Original source 

A parasite that not only feeds of its host, but also makes the host change its own metabolism and thus biology. Microbiologists have shown this for the very first time in a specific group of parasitic microbes, so-called DPANN archea. Their study shows that these archaea are very 'picky eaters', which might drive their hosts to change the menu.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Key functions of therapeutically promising jumbo viruses      (via sciencedaily.com)     Original source 

Viruses known as 'jumbo' phages are seen as a potential tool against deadly bacterial infections. But scientists must first decipher the extraordinary makeup of these mysterious viruses. Researchers have now uncovered a key piece of jumbo phage development that helps them counter bacteria.

Geoscience: Earth Science Geoscience: Earthquakes Geoscience: Geography
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Do earthquake hazard maps predict higher shaking than actually occurred?      (via sciencedaily.com)     Original source 

A research team studied earthquake hazard maps from five countries and found that all the maps seemed to overpredict the historically observed earthquake shaking intensities. In analyzing the possible causes, the researchers discovered the issue was with the conversion equations used in comparing the maps predicting future quakes with actual shaking data, rather than systemic problems with the hazard modeling itself.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Offbeat: General Offbeat: Plants and Animals
Published

Marriage of synthetic biology and 3D printing produces programmable living materials      (via sciencedaily.com)     Original source 

Scientists are harnessing cells to make new types of materials that can grow, repair themselves and even respond to their environment. These solid 'engineered living materials' are made by embedding cells in an inanimate matrix that's formed in a desired shape. Now, researchers have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials. Applications could someday include biomanufacturing and sustainable construction.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Ecology: Endangered Species
Published

Novel genetic plant regeneration approach without the application of phytohormones      (via sciencedaily.com)     Original source 

Conventional plant regeneration approaches by cell culture require the external application of plant growth regulators, including hormones. However, optimizing culture conditions can be laborious. Now, researchers have developed a novel plant regeneration system that omits the need for hormone application by genetically regulating the expression of genes that control plant cell differentiation. Their work holds significant potential in the development of genetically modified plants in a simpler and cost-effective manner.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics
Published

New and improved way to grow the cells that give rise to the kidney's filtration system      (via sciencedaily.com)     Original source 

Scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense promise for understanding kidney development, modeling diseases, and discovering new treatments. The team improved the chemical cocktail for generating and growing NPCs in the laboratory, enabling the sustained growth of both mouse and human NPCs in a simple 2-dimensional format.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Chemistry: Biochemistry Chemistry: General Ecology: Endangered Species Environmental: General Geoscience: Geochemistry
Published

Discovery of mechanism plants use to change seed oil could impact industrial, food oils      (via sciencedaily.com)     Original source 

Researchers have discovered a new mechanism of oil biosynthesis and found a way to genetically engineer a type of test plant to more efficiently produce different kinds of seed oil that it otherwise wouldn't make. While the engineering is proof-of-concept, this discovery could lead to improved production of valuable oils used in food and by a range of industries. The modified plant overcame metabolic bottlenecks and produced significant amounts of an oil similar to castor oil that it doesn't naturally produce.