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Categories: Biology: Biotechnology, Geoscience: Earthquakes
Published Key factors in human-made earthquakes



Researchers report that the roughness of pre-existing faults and associated stress heterogeneity in geological reservoirs play a key role for causing human-made earthquakes, so-called runaway events. The study combines novel fluid injection experiments under acoustic monitoring performed in GFZ's geomechanical laboratory with numerical modelling results.
Published Ancient 'chewing gum' reveals stone age diet



What did people eat on the west coast of Scandinavia 10,000 years ago? A new study of the DNA in a chewing gum shows that deer, trout and hazelnuts were on the diet. It also shows that one of the individuals had severe problems with her teeth.
Published Nearly dead plants brought back to life: Keys to aging hidden in the leaves



Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.
Published Study throws our understanding of gene regulation for a loop



To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies



A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Glowing COVID-19 diagnostic test prototype produces results in one minute



Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.
Published New map shows where damaging earthquakes are most likely to occur in US



Scientists recently revealed the latest National Seismic Hazard Model, showing that nearly 75% of the United States could experience a damaging earthquake, emphasizing seismic hazards span a significant part of the country.
Published Unraveling the role of supersulfides in regulating mitochondrial function and longevity



Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.
Published Bioinformatics: Researchers develop a new machine learning approach



To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published A novel pathway regulating lipid biosynthesis by fatty acids



Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening



A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging



Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published New rice lines for Africa offer virus protection



The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.
Published Spying on a shape-shifting protein



Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Protein complex discovered to control DNA repair



The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published A new type of plant metalloreductase maintains root growth under low phosphorus



Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.
Published Largest diversity study of 'magic mushrooms' investigates the evolution of psychoactive psilocybin production



The genomic analysis of 52 Psilocybe specimens includes 39 species that have never been sequenced. Psilocybe arose much earlier than previously thought -- about 65 million years ago -- and the authors found that psilocybin was first synthesized in mushrooms in the genus Psilocybe. Their analysis revealed two distinct gene orders within the gene cluster that produces psilocybin. The two gene patterns correspond to an ancient split in the genus, suggesting two independent acquisitions of psilocybin in its evolutionary history. The study is the first to reveal such a strong evolutionary pattern within the gene sequences underpinning the psychoactive proteins synthesis.
Published With only the pawprints, researchers study elusive bobcat



With DNA recovered from animal tracks, scientists revealed information about the ancestry and microbial community of bobcats without having to sample the animal directly.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne



An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Large-scale mapping of pig genes could pave the way for new human medicines



Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.