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Categories: Biology: Biotechnology, Geoscience: Earthquakes

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Selective targeting of cancerous cells poses major clinical challenges during cancer therapy. However, this limitation can be overcome by using bioengineered bacteria with highly optimized chemical modifications. A recent study demonstrates the use of chemically modified purple photosynthetic bacteria for the successful detection and elimination of colon cancer cells in a mouse model. The study also sheds light on the underlying mechanism of action.

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Researchers have developed and demonstrated a new method for high-throughput single-cell sorting that uses stimulated Raman spectroscopy rather than the traditional approach of fluorescence-activated cell sorting. The new approach could offer a label-free, nondestructive way to sort cells for a variety of applications, including microbiology, cancer detection and cell therapy.

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The NSL (non-specific lethal) complex regulates thousands of genes in fruit flies and mammals. Silencing the NSL genes leads to the death of the organism, which gave the complex its curious name. Researchers have now discovered that the genes regulated by the NSL complex also include genes of the intraciliary transport system. This enables different cell types to form cilia on their surface, which are important for cell communication. The study shows that these genes are 'switched on' by the NSL complex, regardless of whether a particular cell has cilia or not. The researchers found that this class of cilia-associated genes is crucial for the function of podocytes. This is a highly specialized cell type of the kidney that, paradoxically, does not have cilia. These findings have important implications for ciliopathies and kidney disease.

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Researchers see potential in educational settings for the newest official ChatGPT plugin, called Code Interpreter, they've found limitations for its use by scientists who work with biological data utilizing computational methods to prioritize targeted treatment for cancer and genetic disorders.

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A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression.

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Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression.

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Researchers have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.

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In a groundbreaking endeavor, researchers have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan. The research opens exciting possibilities for unlocking the secrets of aging and extending human lifespan.

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A discovery about how a common insect acquires a microbe that is essential for its growth may help in the control of an agricultural pest.

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Regulatory genes -- genes that control how other genes are used -- are responsible for 69% of the heritability of dairy cattle traits such as milk production and fertility, according to a new study. This contribution is 44% more than expected and much higher than previous studies of regulatory genes in humans. The findings, reported by a team of animal and human geneticists, could improve the efficiency of agricultural breeding programs. The study also helps solve the longstanding mystery of why mammalian genomes contain so much noncoding DNA.

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New research confirms fracking causes slow, small earthquakes or tremors, whose origin was previously a mystery to scientists. The tremors are produced by the same processes that could create large, damaging earthquakes.

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The same fiber optic networks that provide internet can simultaneously act as earthquake sensors, as demonstrated in a new study.

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A new study uses nearly a century of data to show that the average heights of winter waves along the California coast have increased as climate change has heated up the planet.

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Slow earthquakes are slow-slip phenomena that last many days or months, and you barely notice them. In 2007, researchers proposed how the magnitude and duration of earthquakes vary, which can help differentiate slow and fast earthquakes. Seismologists now bolster the proposed relation with more data. They suggest the presence of a speed limit to slow earthquakes and reveal physical processes that differentiate slow and fast earthquakes. Since slow earthquakes could indicate future fast earthquakes, monitoring and understanding them helps accurately forecast devastating earthquakes and tsunamis.

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Much of central Utah's seismic activity comes in groups of small earthquakes. A study by seismologists examines 2,300 quakes occurring 40 'swarms' dating back to 1981, opening a window into Earth's crust in a geothermally active area.

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Scientists used seismic data discovered Earth's inner core displays a variety of textures that it acquired will it formed from within the fluid outer core. The data set was generated over the past 27 years by a network of seismometers set up to enforce the nuclear test ban treaty.

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An international research team has discovered that a subduction zone's age affects the ability for it to recycle water between the Earth's surface and its inner layers. The more mature the subduction zone, the bigger the water storage capacity.

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Scientists have wondered what happens to the organic and inorganic carbon that Earth's Pacific Plate carries with it as it slides into the planet's interior along the volcano-studded Ring of Fire. A new study suggests a notable amount of such subducted carbon returns to the atmosphere rather than traveling deep into Earth's mantle.

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Many factors influence where a landslide will occur, including the shape of the terrain, its slope and drainage areas, the material properties of soil and bedrock, and environmental conditions like climate, rainfall, hydrology and ground motion resulting from earthquakes. Geologists have developed a new technique that uses artificial intelligence to better predict where and why landslides may occur could bolster efforts to protect lives and property in some of the world's most disaster-prone areas. The new method improves the accuracy and interpretability of AI-based machine-learning techniques, requires far less computing power and is more broadly applicable than traditional predictive models.

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An international team has, for the first time, accurately determined the age of the East Anatolian fault, allowing geologists to learn more about its seismic history and tendency to produce earthquakes.