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Categories: Biology: Biotechnology, Geoscience: Earthquakes
Published A new tool to study complex genome interactions
(via sciencedaily.com) Original source Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.
Published Tethering of shattered chromosomal fragments paves way for new cancer therapies
(via sciencedaily.com) Original source Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.
Published Close up on aging reveals how different cell types in the body age at different pace
(via sciencedaily.com) Original source A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Published Plate tectonics not required for the emergence of life
(via sciencedaily.com) Original source New finding contradicts previous assumptions about the role of mobile plate tectonics in the development of life on Earth. Moreover, the data suggests that 'when we're looking for exoplanets that harbor life, the planets do not necessarily need to have plate tectonics,' says the lead author of a new paper.
Published Scientists discover small RNA that regulates bacterial infection
(via sciencedaily.com) Original source Researchers have identified the major mechanism behind the transition between chronic and acute P. aeruginosa infections. Their research findings can inform the development of future treatments for life-threatening acute infections.
Published Study explains unusual deformation in Earth's largest continental rift
(via sciencedaily.com) Original source Computer models confirm that the African Superplume is responsible for the unusual deformations, as well as rift-parallel seismic anisotropy observed beneath the East African Rift System.
Published Scientists investigate the evolution of animal developmental mechanisms, show how some of Earth's earliest animals evolved
(via sciencedaily.com) Original source Lacking bones, brains, and even a complete gut, the body plans of simple animals like sea anemones appear to have little in common with humans and their vertebrate kin. Nevertheless, new research shows that appearances can be deceiving, and that a common genetic toolkit can be deployed in different ways to drive embryological development to produce very different adult body plans. It is well established that sea anemones, corals, and their jellyfish relatives shared a common ancestor with humans that plied the Earth's ancient oceans over 600 million years ago. A new study from the Gibson Lab, published in Current Biology on June 13, 2023, illuminates the genetic basis for body plan development in the starlet sea anemone, Nematostella vectensis. This new knowledge paints a vivid picture of how some of the earliest animals on earth progressed from egg to embryo to adult.
Published CRISPR/Cas9-based gene drive could suppress agricultural pests
(via sciencedaily.com) Original source Researchers have now used a gene-drive system to suppress an important agricultural pest.
Published Campi Flegrei volcano edges closer to possible eruption
(via sciencedaily.com) Original source The new study used a model of volcano fracturing to interpret patterns of earthquakes and ground uplift, and concluded that parts of the volcano had been stretched nearly to breaking point.
Published Taurine may be a key to longer and healthier life
(via sciencedaily.com) Original source A study finds that deficiency of taurine, a molecule produced in our bodies, drives aging, and taurine supplements can improve health and increase lifespan in animals.
Published When water temperatures change, the molecular motors of cephalopods do too
(via sciencedaily.com) Original source Working with live squid hatchlings, scientists find the animals can tune their proteome on the fly in response to changes in ocean temperature via the unique process of RNA recoding. The findings inspire new questions about basic protein function.
Published Octopuses rewire their brains to adapt to seasonal temperature shifts
(via sciencedaily.com) Original source Octopuses don't thermoregulate, so their powerful brains are exposed to -- and potentially threatened by -- changes in temperature. Researchers report that two-spot octopuses adapt to seasonal temperature shifts by producing different neural proteins under warm versus cool conditions. The octopuses achieve this by editing their RNA, the messenger molecule between DNA and proteins. This rewiring likely protects their brains, and the researchers suspect that this unusual strategy is used widely amongst octopuses and squid.
Published Remains of an extinct world of organisms discovered
(via sciencedaily.com) Original source Newly discovered biomarker signatures point to a whole range of previously unknown organisms that dominated complex life on Earth about a billion years ago. They differed from complex eukaryotic life as we know it, such as animals, plants and algae in their cell structure and likely metabolism, which was adapted to a world that had far less oxygen in the atmosphere than today.
Published Bubble, bubble, more earthquake trouble? Geoscientists study Alaska's Denali fault
(via sciencedaily.com) Original source Geochemists report findings from collected and analyzed helium and carbon isotopic data from springs along a nearly 250-mile segment of Alaska's Denali Fault. The fault's mantle fluid flow rates, they report, fall in the range observed for the world's other major and active strike-slip faults that form plate boundaries.
Published Biological clocks of people and malaria parasites tick in tune
(via sciencedaily.com) Original source Could the next weapon against malaria come from a better understanding of biological clocks? A new study shows that malaria parasites sync their gene activity with the circadian rhythms of their host, like two pendulum clocks with synchronized swings. If scientists can identify the molecular signals behind this mysterious synchronicity, they might be able to develop new anti-malarial drugs that throw malaria's internal clock out of step with its host, essentially 'jet-lagging' the parasites.
Published Older trees accumulate more mutations than their younger counterparts
(via sciencedaily.com) Original source A study of the relationship between the growth rate of tropical trees and the frequency of genetic mutations they accumulate suggests that older, long-lived trees play a greater role in generating and maintaining genetic diversity than short-lived trees.
Published A compound from fruit flies could lead to new antibiotics
(via sciencedaily.com) Original source Research shows that the natural peptide, called drosocin, protects fruit flies from bacterial infections by binding to ribosomes in bacteria. Once bound, drosocin prevents the ribosome from making new proteins.
Published Previously unknown antibiotic resistance widespread among bacteria
(via sciencedaily.com) Original source Genes that make bacteria resistant to antibiotics are much more widespread in our environment than was previously realized. A new study shows that bacteria in almost all environments carry resistance genes, with a risk of them spreading and aggravating the problem of bacterial infections that are untreatable with antibiotics.
Published Genomes of 233 primate species sequenced
(via sciencedaily.com) Original source Researchers from 24 countries have analyzed the genomes of 809 individuals from 233 primate species, generating the most complete catalog of genomic information about our closest relatives to date. The project provides new insights into the evolution of primates, including humans, and their diversity. In baboons, for example, hybridization and gene flow between different species occurred in the past and is still ongoing in several regions of their range. This makes baboons a good model for the evolution of early human lineages within and outside Africa. In addition, using a specially designed AI algorithm, the genomic data enable new insights into the genetic causes of human diseases.
Published Ancient viruses discovered in coral symbionts' DNA
(via sciencedaily.com) Original source The symbiotic organisms that live in corals and provide them with their dramatic colors contain fragments of ancient RNA viruses that are as much as 160 million years old.